Biosynthesis of fungal indole alkaloids W Xu, DJ Gavia, Y Tang Natural product reports 31 (10), 1474-1487, 2014 | 194 | 2014 |
The Fumagillin Biosynthetic Gene Cluster in Aspergillus fumigatus Encodes a Cryptic Terpene Cyclase Involved in the Formation of β-trans-Bergamotene HC Lin, YH Chooi, S Dhingra, W Xu, AM Calvo, Y Tang Journal of the American Chemical Society 135 (12), 4616-4619, 2013 | 185 | 2013 |
Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation AO Zabala, W Xu, YH Chooi, Y Tang Chemistry & biology 19 (8), 1049-1059, 2012 | 156 | 2012 |
LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis. W Xu, YH Chooi, JW Choi, S Li, JC Vederas, NA Da Silva, Y Tang Angewandte Chemie 125 (25), 2013 | 136 | 2013 |
Analysis of Intact and Dissected Fungal Polyketide Synthase-Nonribosomal Peptide Synthetase in Vitro and in Saccharomyces cerevisiae W Xu, X Cai, ME Jung, Y Tang Journal of the American Chemical Society 132 (39), 13604-13607, 2010 | 130 | 2010 |
Acyltransferase mediated polyketide release from a fungal megasynthase X Xie, MJ Meehan, W Xu, PC Dorrestein, Y Tang Journal of the American Chemical Society 131 (24), 8388-8389, 2009 | 119 | 2009 |
Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains Y Li, W Xu, Y Tang The Journal of biological chemistry 285 (30), 22764, 2010 | 115 | 2010 |
Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids HC Lin, G Chiou, YH Chooi, TC McMahon, W Xu, NK Garg, Y Tang Angewandte Chemie International Edition 54 (10), 3004-3007, 2015 | 107 | 2015 |
Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway HC Lin, Y Tsunematsu, S Dhingra, W Xu, M Fukutomi, YH Chooi, ... Journal of the American Chemical Society 136 (11), 4426-4436, 2014 | 103 | 2014 |
Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis BD Ames, C Nguyen, J Bruegger, P Smith, W Xu, S Ma, E Wong, S Wong, ... Proceedings of the National Academy of Sciences 109 (28), 11144-11149, 2012 | 101 | 2012 |
Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products XM Mao, W Xu, D Li, WB Yin, YH Chooi, YQ Li, Y Tang, Y Hu Angewandte Chemie 127 (26), 7702-7706, 2015 | 97 | 2015 |
Discovery of unclustered fungal indole diterpene biosynthetic pathways through combinatorial pathway reassembly in engineered yeast MC Tang, HC Lin, D Li, Y Zou, J Li, W Xu, RA Cacho, ME Hillenmeyer, ... Journal of the American Chemical Society 137 (43), 13724-13727, 2015 | 95 | 2015 |
Efficient biosynthesis of fungal polyketides containing the dioxabicyclo-octane ring system XM Mao, ZJ Zhan, MN Grayson, MC Tang, W Xu, YQ Li, WB Yin, HC Lin, ... Journal of the American Chemical Society 137 (37), 11904-11907, 2015 | 94 | 2015 |
A carbonate-forming Baeyer-Villiger monooxygenase Y Hu, D Dietrich, W Xu, A Patel, JAJ Thuss, J Wang, WB Yin, K Qiao, ... Nature chemical biology 10 (7), 552-554, 2014 | 93 | 2014 |
Involvement of lipocalin‐like CghA in decalin‐forming stereoselective intramolecular [4+ 2] cycloaddition M Sato, F Yagishita, T Mino, N Uchiyama, A Patel, YH Chooi, Y Goda, ... ChemBioChem 16 (16), 2294-2298, 2015 | 87 | 2015 |
Genome mining and assembly-line biosynthesis of the UCS1025A pyrrolizidinone family of fungal alkaloids L Li, MC Tang, S Tang, S Gao, S Soliman, L Hang, W Xu, T Ye, ... Journal of the American Chemical Society 140 (6), 2067-2071, 2018 | 66 | 2018 |
Understanding programming of fungal iterative polyketide synthases: the biochemical basis for regioselectivity by the methyltransferase domain in the lovastatin megasynthase RA Cacho, J Thuss, W Xu, R Sanichar, Z Gao, A Nguyen, JC Vederas, ... Journal of the American Chemical Society 137 (50), 15688-15691, 2015 | 64 | 2015 |
Structural analysis of protein–protein interactions in type I polyketide synthases W Xu, K Qiao, Y Tang Critical reviews in biochemistry and molecular biology 48 (2), 98-122, 2013 | 59 | 2013 |
P450-mediated coupling of indole fragments to forge communesin and unnatural isomers HC Lin, TC McMahon, A Patel, M Corsello, A Simon, W Xu, M Zhao, ... Journal of the American Chemical Society 138 (12), 4002-4005, 2016 | 58 | 2016 |
Production of new cladosporin analogues by reconstitution of the polyketide synthases responsible for the biosynthesis of this antimalarial agent RVK Cochrane, R Sanichar, GR Lambkin, B Reiz, W Xu, Y Tang, ... Angewandte Chemie 128 (2), 674-678, 2016 | 57 | 2016 |