| The role of interleukin-2 during homeostasis and activation of the immune system O Boyman, J Sprent Nature Reviews Immunology 12 (3), 180-190, 2012 | 1895 | 2012 |
| Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15 X Zhang, S Sun, I Hwang, DF Tough, J Sprent Immunity 8 (5), 591-599, 1998 | 1581 | 1998 |
| Homeostasis of naive and memory T cells CD Surh, J Sprent Immunity 29 (6), 848-862, 2008 | 1508 | 2008 |
| T-cell apoptosis detected in situ during positive and negative selection in the thymus CD Surh, J Sprent Nature 372 (6501), 100-103, 1994 | 1373 | 1994 |
| Induction of bystander T cell proliferation by viruses and type I interferon in vivo DF Tough, P Borrow, J Sprent Science 272 (5270), 1947-1950, 1996 | 1325 | 1996 |
| IL-7 is critical for homeostatic proliferation and survival of naive T cells JT Tan, E Dudl, E LeRoy, R Murray, J Sprent, KI Weinberg, CD Surh Proceedings of the National Academy of Sciences 98 (15), 8732-8737, 2001 | 1214 | 2001 |
| Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection GA Kolumam, S Thomas, LJ Thompson, J Sprent, K Murali-Krishna The Journal of experimental medicine 202 (5), 637-650, 2005 | 1170 | 2005 |
| Turnover of naive-and memory-phenotype T cells. DF Tough, J Sprent The Journal of experimental medicine 179 (4), 1127-1135, 1994 | 1097 | 1994 |
| Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity S Webb, C Morris, J Sprent Cell 63 (6), 1249-1256, 1990 | 1088 | 1990 |
| Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells JT Tan, B Ernst, WC Kieper, E LeRoy, J Sprent, CD Surh The Journal of experimental medicine 195 (12), 1523-1532, 2002 | 1014 | 2002 |
| Selective stimulation of T cell subsets with antibody-cytokine immune complexes O Boyman, M Kovar, MP Rubinstein, CD Surh, J Sprent Science 311 (5769), 1924-1927, 2006 | 1007 | 2006 |
| Cellular and genetic mechanisms of self tolerance and autoimmunity CC Goodnow, J Sprent, BF de St Groth, CG Vinuesa Nature 435 (7042), 590-597, 2005 | 939 | 2005 |
| The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery B Ernst, DS Lee, JM Chang, J Sprent, CD Surh Immunity 11 (2), 173-181, 1999 | 936 | 1999 |
| A fundamental role for interleukin-21 in the generation of T follicular helper cells A Vogelzang, HM McGuire, D Yu, J Sprent, CR Mackay, C King Immunity 29 (1), 127-137, 2008 | 907 | 2008 |
| T cell memory J Sprent, CD Surh Annual review of immunology 20 (1), 551-579, 2002 | 793 | 2002 |
| Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. R Korngold, J Sprent The Journal of experimental medicine 148 (6), 1687-1698, 1978 | 717 | 1978 |
| A monoclonal antibody discriminating between subsets of T and B cells. J Bruce, FW Symington, TJ McKearn, J Sprent Journal of immunology (Baltimore, Md.: 1950) 127 (6), 2496-2501, 1981 | 694 | 1981 |
| A RECEPTOR FOR ANTIBODY ON B LYMPHOCYTES: I. METHOD OF DETECTION AND FUNCTIONAL SIGNIFICANCE A Basten, J Miller, J Sprent, J Pye The Journal of Experimental Medicine 135 (3), 610-626, 1972 | 647 | 1972 |
| In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression KE Webster, S Walters, RE Kohler, T Mrkvan, O Boyman, CD Surh, ... Journal of Experimental Medicine 206 (4), 751-760, 2009 | 589 | 2009 |
| TCR-Mediated internalization of peptide-MHC complexes acquired by T cells JF Huang, Y Yang, H Sepulveda, W Shi, I Hwang, PA Peterson, ... Science 286 (5441), 952-954, 1999 | 568 | 1999 |
David ToughGSKVerified email at gsk.com
