| MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation BC Lee, Z Péterfi, FKW Hoffmann, RE Moore, A Kaya, A Avanesov, ... Molecular cell 51 (3), 397-404, 2013 | 249 | 2013 |
| Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status BC Lee, A Kaya, S Ma, G Kim, MV Gerashchenko, SH Yim, Z Hu, ... Nature communications 5 (1), 3592, 2014 | 246 | 2014 |
| Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide DE Fomenko, A Koc, N Agisheva, M Jacobsen, A Kaya, M Malinouski, ... Proceedings of the National Academy of Sciences 108 (7), 2729-2734, 2011 | 176 | 2011 |
| Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater X Zhou, X Guang, D Sun, S Xu, M Li, I Seim, W Jie, L Yang, Q Zhu, J Xu, ... Nature communications 9 (1), 1276, 2018 | 118 | 2018 |
| Methionine restriction and life‐span control BC Lee, A Kaya, VN Gladyshev Annals of the New York Academy of Sciences 1363 (1), 116-124, 2016 | 103 | 2016 |
| Functional analysis of free methionine-R-sulfoxide reductase from Saccharomyces cerevisiae DT Le, BC Lee, SM Marino, Y Zhang, DE Fomenko, A Kaya, E Hacioglu, ... Journal of Biological Chemistry 284 (7), 4354-4364, 2009 | 98 | 2009 |
| Taurine deficiency as a driver of aging P Singh, K Gollapalli, S Mangiola, D Schranner, MA Yusuf, M Chamoli, ... Science 380 (6649), eabn9257, 2023 | 96 | 2023 |
| Methionine sulfoxide reductases preferentially reduce unfolded oxidized proteins and protect cells from oxidative protein unfolding L Tarrago, A Kaya, E Weerapana, SM Marino, VN Gladyshev Journal of Biological Chemistry 287 (29), 24448-24459, 2012 | 95 | 2012 |
| Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast A Kaya, HC Karakaya, DE Fomenko, VN Gladyshev, A Koc Molecular and Cellular Biology 29 (13), 3665-3674, 2009 | 94 | 2009 |
| Regulation of protein function by reversible methionine oxidation and the role of selenoprotein MsrB1 A Kaya, BC Lee, VN Gladyshev Antioxidants & redox signaling 23 (10), 814-822, 2015 | 88 | 2015 |
| Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response VM Labunskyy, MV Gerashchenko, JR Delaney, A Kaya, BK Kennedy, ... PLoS Genetics 10 (1), e1004019, 2014 | 88 | 2014 |
| Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae A Kaya, AV Lobanov, VN Gladyshev Aging cell 14 (3), 366-371, 2015 | 79 | 2015 |
| Characterization of methionine oxidation and methionine sulfoxide reduction using methionine-rich cysteine-free proteins X Liang, A Kaya, Y Zhang, DT Le, D Hua, VN Gladyshev BMC biochemistry 13, 1-10, 2012 | 75 | 2012 |
| Boron stress activates the general amino acid control mechanism and inhibits protein synthesis I Uluisik, A Kaya, DE Fomenko, HC Karakaya, BA Carlson, VN Gladyshev, ... PLoS One 6 (11), e27772, 2011 | 64 | 2011 |
| Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins A Kaya, MV Gerashchenko, I Seim, J Labarre, MB Toledano, ... Proceedings of the National Academy of Sciences 112 (34), 10685-10690, 2015 | 54 | 2015 |
| Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna AV Shindyapina, Y Cho, A Kaya, A Tyshkovskiy, JP Castro, A Deik, ... Science advances 8 (37), eabo5482, 2022 | 45 | 2022 |
| Compartmentalization and regulation of mitochondrial function by methionine sulfoxide reductases in yeast A Kaya, A Koc, BC Lee, DE Fomenko, M Rederstorff, A Krol, A Lescure, ... Biochemistry 49 (39), 8618-8625, 2010 | 37 | 2010 |
| Beaver and naked mole rat genomes reveal common paths to longevity X Zhou, Q Dou, G Fan, Q Zhang, M Sanderford, A Kaya, J Johnson, ... Cell reports 32 (4), 2020 | 32 | 2020 |
| Diversity of plant methionine sulfoxide reductases B and evolution of a form specific for free methionine sulfoxide DT Le, L Tarrago, Y Watanabe, A Kaya, BC Lee, U Tran, R Nishiyama, ... PloS one 8 (6), e65637, 2013 | 31 | 2013 |
| Genome-wide identification of genes that play a role in boron stress response in yeast I Uluisik, A Kaya, ES Unlu, K Avsar, HC Karakaya, T Yalcin, A Koc Genomics 97 (2), 106-111, 2011 | 25 | 2011 |
Vadim GladyshevProfessor of Medicine, Brigham and Women's Hospital, Harvard Medical SchoolVerified email at rics.bwh.harvard.edu
