|Structural analysis of a set of proteins resulting from a bacterial genomics project|
J Badger, JM Sauder, JM Adams, S Antonysamy, K Bain, MG Bergseid, ...
Proteins: Structure, Function, and Bioinformatics 60 (4), 787-796, 2005
|Haloalkane dehalogenases: structure of a Rhodococcus enzyme|
J Newman, S Thomas, R Richard, L Kan, PE Swanson, JA Affholter, ...
Biochemistry 38 (49), 16105-16114, 1999
|Structure of the UmuD′ protein and its regulation in response to DNA damage|
TS Peat, EG Frank, JP McDonald, AS Levine, R Woodgate, ...
Nature 380 (6576), 727-730, 1996
|Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 ┼ resolution|
TS Peat, J Newman, GS Waldo, J Berendzen, TC Terwilliger
Structure 6 (9), 1207-1214, 1998
|A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs|
HA Lewis, EB Furlong, B Laubert, GA Eroshkina, Y Batiyenko, JM Adams, ...
Structure 9 (6), 527-537, 2001
|Identification and characterization of two families of F420H2‐dependent reductases from Mycobacteria that catalyse aflatoxin degradation|
MC Taylor, CJ Jackson, DB Tattersall, N French, TS Peat, J Newman, ...
Molecular microbiology 78 (3), 561-575, 2010
|Cryo-EM structure of the active, G s-protein complexed, human CGRP receptor|
YL Liang, M Khoshouei, G Deganutti, A Glukhova, C Koole, TS Peat, ...
Nature 561 (7724), 492-497, 2018
|Class‐directed structure determination: Foundation for a protein structure initiative|
TC Terwilliger, G Waldo, TS Peat, JM Newman, KC And, J Berendzen
Protein Science 7 (9), 1851-1856, 1998
|Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses|
AJ Oakley, S Barrett, TS Peat, J Newman, VA Streltsov, L Waddington, ...
American Chemical Society, 2010
|A PMMA microfluidic droplet platform for in vitro protein expression using crude E. coli S30 extract|
N Wu, Y Zhu, S Brown, J Oakeshott, TS Peat, R Surjadi, C Easton, ...
Lab on a Chip 9 (23), 3391-3398, 2009
|Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?|
J Wielens, SJ Headey, DI Rhodes, RJ Mulder, O Dolezal, JJ Deadman, ...
Journal of biomolecular screening 18 (2), 147-159, 2013
|Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes|
J Moeker, TS Peat, LF Bornaghi, D Vullo, CT Supuran, SA Poulsen
Journal of medicinal chemistry 57 (8), 3522-3531, 2014
|Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth|
JB Baell, DJ Leaver, SJ Hermans, GL Kelly, MS Brennan, NL Downer, ...
Nature 560 (7717), 253-257, 2018
|Crystal structure of an indole-3-acetic acid amido synthetase from grapevine involved in auxin homeostasis|
TS Peat, C B÷ttcher, J Newman, D Lucent, N Cowieson, C Davies
The Plant Cell 24 (11), 4525-4538, 2012
|Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site|
RP Tanpure, B Ren, TS Peat, LF Bornaghi, D Vullo, CT Supuran, ...
Journal of Medicinal Chemistry 58 (3), 1494-1501, 2015
|Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design|
TS Peat, DI Rhodes, N Vandegraaff, G Le, JA Smith, LJ Clark, ED Jones, ...
PloS one 7 (7), e40147, 2012
|Tapping the Protein Data Bank for crystallization information|
TS Peat, JA Christopher, J Newman
Acta Crystallographica Section D: Biological Crystallography 61 (12), 1662-1669, 2005
|Structural Basis for a New Mechanism of Inhibition of HI V-1 Integrase Identified by Fragment Screening and Structure-Based Design|
DI Rhodes, TS Peat, N Vandegraaff, D Jeevarajah, G Le, ED Jones, ...
Antiviral Chemistry and Chemotherapy 21 (4), 155-168, 2011
|Solution structure of Pyrobaculum aerophilum DsrC, an archaeal homologue of the gamma subunit of dissimilatory sulfite reductase|
JR Cort, SVS Mariappan, CY Kim, MS Park, TS Peat, GS Waldo, ...
European Journal of Biochemistry 268 (22), 5842-5850, 2001
|A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo|
DT Dransfield, EH Cohen, Q Chang, LG Sparrow, JD Bentley, O Dolezal, ...
Molecular cancer therapeutics 9 (6), 1809-1819, 2010