Tom Peat
Tom Peat
scientist, CSIRO
Verified email at csiro.au
Title
Cited by
Cited by
Year
Structural analysis of a set of proteins resulting from a bacterial genomics project
J Badger, JM Sauder, JM Adams, S Antonysamy, K Bain, MG Bergseid, ...
Proteins: Structure, Function, and Bioinformatics 60 (4), 787-796, 2005
2482005
Haloalkane dehalogenases: structure of a Rhodococcus enzyme
J Newman, S Thomas, R Richard, L Kan, PE Swanson, JA Affholter, ...
Biochemistry 38 (49), 16105-16114, 1999
2321999
Structure of the UmuD′ protein and its regulation in response to DNA damage
TS Peat, EG Frank, JP McDonald, AS Levine, R Woodgate, ...
Nature 380 (6576), 727-730, 1996
1661996
Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 ┼ resolution
TS Peat, J Newman, GS Waldo, J Berendzen, TC Terwilliger
Structure 6 (9), 1207-1214, 1998
1361998
A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs
HA Lewis, EB Furlong, B Laubert, GA Eroshkina, Y Batiyenko, JM Adams, ...
Structure 9 (6), 527-537, 2001
1212001
Identification and characterization of two families of F420H2‐dependent reductases from Mycobacteria that catalyse aflatoxin degradation
MC Taylor, CJ Jackson, DB Tattersall, N French, TS Peat, J Newman, ...
Molecular microbiology 78 (3), 561-575, 2010
1122010
Cryo-EM structure of the active, G s-protein complexed, human CGRP receptor
YL Liang, M Khoshouei, G Deganutti, A Glukhova, C Koole, TS Peat, ...
Nature 561 (7724), 492-497, 2018
1072018
Class‐directed structure determination: Foundation for a protein structure initiative
TC Terwilliger, G Waldo, TS Peat, JM Newman, KC And, J Berendzen
Protein Science 7 (9), 1851-1856, 1998
1061998
Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses
AJ Oakley, S Barrett, TS Peat, J Newman, VA Streltsov, L Waddington, ...
American Chemical Society, 2010
992010
A PMMA microfluidic droplet platform for in vitro protein expression using crude E. coli S30 extract
N Wu, Y Zhu, S Brown, J Oakeshott, TS Peat, R Surjadi, C Easton, ...
Lab on a Chip 9 (23), 3391-3398, 2009
712009
Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Wielens, SJ Headey, DI Rhodes, RJ Mulder, O Dolezal, JJ Deadman, ...
Journal of biomolecular screening 18 (2), 147-159, 2013
692013
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes
J Moeker, TS Peat, LF Bornaghi, D Vullo, CT Supuran, SA Poulsen
Journal of medicinal chemistry 57 (8), 3522-3531, 2014
682014
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
JB Baell, DJ Leaver, SJ Hermans, GL Kelly, MS Brennan, NL Downer, ...
Nature 560 (7717), 253-257, 2018
672018
Crystal structure of an indole-3-acetic acid amido synthetase from grapevine involved in auxin homeostasis
TS Peat, C B÷ttcher, J Newman, D Lucent, N Cowieson, C Davies
The Plant Cell 24 (11), 4525-4538, 2012
582012
Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site
RP Tanpure, B Ren, TS Peat, LF Bornaghi, D Vullo, CT Supuran, ...
Journal of Medicinal Chemistry 58 (3), 1494-1501, 2015
522015
Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design
TS Peat, DI Rhodes, N Vandegraaff, G Le, JA Smith, LJ Clark, ED Jones, ...
PloS one 7 (7), e40147, 2012
522012
Tapping the Protein Data Bank for crystallization information
TS Peat, JA Christopher, J Newman
Acta Crystallographica Section D: Biological Crystallography 61 (12), 1662-1669, 2005
522005
Structural Basis for a New Mechanism of Inhibition of HI V-1 Integrase Identified by Fragment Screening and Structure-Based Design
DI Rhodes, TS Peat, N Vandegraaff, D Jeevarajah, G Le, ED Jones, ...
Antiviral Chemistry and Chemotherapy 21 (4), 155-168, 2011
512011
Solution structure of Pyrobaculum aerophilum DsrC, an archaeal homologue of the gamma subunit of dissimilatory sulfite reductase
JR Cort, SVS Mariappan, CY Kim, MS Park, TS Peat, GS Waldo, ...
European Journal of Biochemistry 268 (22), 5842-5850, 2001
482001
A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo
DT Dransfield, EH Cohen, Q Chang, LG Sparrow, JD Bentley, O Dolezal, ...
Molecular cancer therapeutics 9 (6), 1809-1819, 2010
442010
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