Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes D Perera, RC Poulos, A Shah, D Beck, JE Pimanda, JWH Wong Nature 532 (7598), 259-263, 2016 | 221 | 2016 |
WDR5 supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma Y Sun, JL Bell, D Carter, S Gherardi, RC Poulos, G Milazzo, JWH Wong, ... Cancer research 75 (23), 5143-5154, 2015 | 102 | 2015 |
Strategies to enable large-scale proteomics for reproducible research RC Poulos, PG Hains, R Shah, N Lucas, D Xavier, SS Manda, A Anees, ... Nature communications 11 (1), 3793, 2020 | 78 | 2020 |
The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes RC Poulos, J Olivier, JWH Wong Nucleic acids research 45 (13), 7786-7795, 2017 | 78 | 2017 |
Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif RC Poulos, JAI Thoms, YF Guan, A Unnikrishnan, JE Pimanda, ... Cell reports 17 (11), 2865-2872, 2016 | 76 | 2016 |
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription M Wong, AEL Tee, G Milazzo, JL Bell, RC Poulos, B Atmadibrata, Y Sun, ... Cancer research 77 (9), 2522-2533, 2017 | 66 | 2017 |
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma M Wong, Y Sun, Z Xi, G Milazzo, RC Poulos, C Bartenhagen, JL Bell, ... Nature Communications 10 (1), 3319, 2019 | 64 | 2019 |
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia D Jing, Y Huang, X Liu, KCS Sia, JC Zhang, X Tai, M Wang, CE Toscan, ... Cancer cell 34 (6), 906-921. e8, 2018 | 60 | 2018 |
Machine learning for multi-omics data integration in cancer Z Cai, RC Poulos, J Liu, Q Zhong Iscience, 2022 | 58 | 2022 |
Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations RC Poulos, YT Wong, R Ryan, H Pang, JWH Wong PLoS genetics 14 (11), e1007779, 2018 | 50 | 2018 |
Pan-cancer proteomic map of 949 human cell lines E Gonçalves, RC Poulos, Z Cai, S Barthorpe, SS Manda, N Lucas, A Beck, ... Cancer Cell 40 (8), 835-849. e8, 2022 | 43 | 2022 |
Role of POT1 in human cancer Y Wu, RC Poulos, RR Reddel Cancers 12 (10), 2739, 2020 | 38 | 2020 |
Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome RC Poulos, JAI Thoms, A Shah, D Beck, JE Pimanda, JWH Wong Molecular Cancer Research 13 (8), 1218-1226, 2015 | 29 | 2015 |
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer H Fang, JA Barbour, RC Poulos, R Katainen, LA Aaltonen, JWH Wong PLoS genetics 16 (2), e1008572, 2020 | 28 | 2020 |
Finding cancer driver mutations in the era of big data research RC Poulos, JWH Wong Biophysical reviews 11 (1), 21-29, 2019 | 25 | 2019 |
OncoCis: annotation of cis-regulatory mutations in cancer D Perera, D Chacon, JAI Thoms, RC Poulos, A Shlien, D Beck, ... Genome biology 15 (10), 1-14, 2014 | 25 | 2014 |
The search for cis-regulatory driver mutations in cancer genomes RC Poulos, MA Sloane, LB Hesson, JWH Wong Oncotarget 6 (32), 32509, 2015 | 21 | 2015 |
Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation MJ Morris, LB Hesson, RC Poulos, RL Ward, JWH Wong, NA Youngson Biomarker research 6 (1), 1-8, 2018 | 15 | 2018 |
Disruption of a −35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells Q Liu, JAI Thoms, AC Nunez, Y Huang, K Knezevic, D Packham, ... Clinical Cancer Research 24 (18), 4602-4611, 2018 | 13 | 2018 |
Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples S Ma, R Menon, RC Poulos, JWH Wong Oncotarget 8 (56), 95841, 2017 | 10 | 2017 |