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Rebecca C Poulos
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Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes
D Perera, RC Poulos, A Shah, D Beck, JE Pimanda, JWH Wong
Nature 532 (7598), 259-263, 2016
1902016
WDR5 supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma
Y Sun, JL Bell, D Carter, S Gherardi, RC Poulos, G Milazzo, JWH Wong, ...
Cancer research 75 (23), 5143-5154, 2015
672015
The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes
RC Poulos, J Olivier, JWH Wong
Nucleic acids research 45 (13), 7786-7795, 2017
592017
Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif
RC Poulos, JAI Thoms, YF Guan, A Unnikrishnan, JE Pimanda, ...
Cell reports 17 (11), 2865-2872, 2016
572016
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription
M Wong, AEL Tee, G Milazzo, JL Bell, RC Poulos, B Atmadibrata, Y Sun, ...
Cancer research 77 (9), 2522-2533, 2017
502017
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia
D Jing, Y Huang, X Liu, KCS Sia, JC Zhang, X Tai, M Wang, CE Toscan, ...
Cancer cell 34 (6), 906-921. e8, 2018
482018
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma
M Wong, Y Sun, Z Xi, G Milazzo, RC Poulos, C Bartenhagen, JL Bell, ...
Nature communications 10 (1), 1-15, 2019
352019
Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations
RC Poulos, YT Wong, R Ryan, H Pang, JWH Wong
PLoS genetics 14 (11), e1007779, 2018
342018
Systematic screening of promoter regions pinpoints functional cis-regulatory mutations in a cutaneous melanoma genome
RC Poulos, JAI Thoms, A Shah, D Beck, JE Pimanda, JWH Wong
Molecular Cancer Research 13 (8), 1218-1226, 2015
282015
Strategies to enable large-scale proteomics for reproducible research
RC Poulos, PG Hains, R Shah, N Lucas, D Xavier, SS Manda, A Anees, ...
Nature communications 11 (1), 1-13, 2020
272020
OncoCis: annotation of cis-regulatory mutations in cancer
D Perera, D Chacon, JAI Thoms, RC Poulos, A Shlien, D Beck, ...
Genome biology 15 (10), 1-14, 2014
232014
Finding cancer driver mutations in the era of big data research
RC Poulos, JWH Wong
Biophysical reviews 11 (1), 21-29, 2019
212019
Role of POT1 in human cancer
Y Wu, RC Poulos, RR Reddel
Cancers 12 (10), 2739, 2020
202020
The search for cis-regulatory driver mutations in cancer genomes
RC Poulos, MA Sloane, LB Hesson, JWH Wong
Oncotarget 6 (32), 32509, 2015
192015
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer
H Fang, JA Barbour, RC Poulos, R Katainen, LA Aaltonen, JWH Wong
PLoS genetics 16 (2), e1008572, 2020
182020
Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation
MJ Morris, LB Hesson, RC Poulos, RL Ward, JWH Wong, NA Youngson
Biomarker research 6 (1), 1-8, 2018
132018
Disruption of a− 35 kb enhancer impairs CTCF binding and MLH1 expression in colorectal cells
Q Liu, JAI Thoms, AC Nunez, Y Huang, K Knezevic, D Packham, ...
Clinical Cancer Research 24 (18), 4602-4611, 2018
112018
Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples
S Ma, R Menon, RC Poulos, JWH Wong
Oncotarget 8 (56), 95841, 2017
92017
Scarcity of recurrent regulatory driver mutations in colorectal cancer revealed by targeted deep sequencing
RC Poulos, D Perera, D Packham, A Shah, C Janitz, JE Pimanda, ...
JNCI cancer spectrum 3 (2), pkz012, 2019
32019
Cis-regulatory driver mutations in cancer genomes
RC Poulos, JWH Wong
eLS, 1-10, 2017
32017
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