|Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes|
D Perera, RC Poulos, A Shah, D Beck, JE Pimanda, JWH Wong
Nature 532 (7598), 259-263, 2016
|WDR5 supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma|
Y Sun, JL Bell, D Carter, S Gherardi, RC Poulos, G Milazzo, JWH Wong, ...
Cancer research 75 (23), 5143-5154, 2015
|The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes|
RC Poulos, J Olivier, JWH Wong
Nucleic acids research 45 (13), 7786-7795, 2017
|Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif|
RC Poulos, JAI Thoms, YF Guan, A Unnikrishnan, JE Pimanda, ...
Cell reports 17 (11), 2865-2872, 2016
|The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription|
M Wong, AEL Tee, G Milazzo, JL Bell, RC Poulos, B Atmadibrata, Y Sun, ...
Cancer research 77 (9), 2522-2533, 2017
|Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia|
D Jing, Y Huang, X Liu, KCS Sia, JC Zhang, X Tai, M Wang, CE Toscan, ...
Cancer cell 34 (6), 906-921. e8, 2018
|JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma|
M Wong, Y Sun, Z Xi, G Milazzo, RC Poulos, C Bartenhagen, JL Bell, ...
Nature communications 10 (1), 1-15, 2019
|Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations|
RC Poulos, YT Wong, R Ryan, H Pang, JWH Wong
PLoS genetics 14 (11), e1007779, 2018
|Systematic screening of promoter regions pinpoints functional cis-regulatory mutations in a cutaneous melanoma genome|
RC Poulos, JAI Thoms, A Shah, D Beck, JE Pimanda, JWH Wong
Molecular Cancer Research 13 (8), 1218-1226, 2015
|Strategies to enable large-scale proteomics for reproducible research|
RC Poulos, PG Hains, R Shah, N Lucas, D Xavier, SS Manda, A Anees, ...
Nature communications 11 (1), 1-13, 2020
|OncoCis: annotation of cis-regulatory mutations in cancer|
D Perera, D Chacon, JAI Thoms, RC Poulos, A Shlien, D Beck, ...
Genome biology 15 (10), 1-14, 2014
|Finding cancer driver mutations in the era of big data research|
RC Poulos, JWH Wong
Biophysical reviews 11 (1), 21-29, 2019
|Role of POT1 in human cancer|
Y Wu, RC Poulos, RR Reddel
Cancers 12 (10), 2739, 2020
|The search for cis-regulatory driver mutations in cancer genomes|
RC Poulos, MA Sloane, LB Hesson, JWH Wong
Oncotarget 6 (32), 32509, 2015
|Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer|
H Fang, JA Barbour, RC Poulos, R Katainen, LA Aaltonen, JWH Wong
PLoS genetics 16 (2), e1008572, 2020
|Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation|
MJ Morris, LB Hesson, RC Poulos, RL Ward, JWH Wong, NA Youngson
Biomarker research 6 (1), 1-8, 2018
|Disruption of a− 35 kb enhancer impairs CTCF binding and MLH1 expression in colorectal cells|
Q Liu, JAI Thoms, AC Nunez, Y Huang, K Knezevic, D Packham, ...
Clinical Cancer Research 24 (18), 4602-4611, 2018
|Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples|
S Ma, R Menon, RC Poulos, JWH Wong
Oncotarget 8 (56), 95841, 2017
|Scarcity of recurrent regulatory driver mutations in colorectal cancer revealed by targeted deep sequencing|
RC Poulos, D Perera, D Packham, A Shah, C Janitz, JE Pimanda, ...
JNCI cancer spectrum 3 (2), pkz012, 2019
|Cis-regulatory driver mutations in cancer genomes|
RC Poulos, JWH Wong
eLS, 1-10, 2017