Mitochondrial ribosomal RNA mutation associated with both antibiotic–induced and non–syndromic deafness TR Prezant, JV Agapian, MC Bohlman, X Bu, S Öztas, WQ Qiu, KS Arnos, ... Nature genetics 4 (3), 289-294, 1993 | 1610 | 1993 |
Detection of a specific mitochondrial DNA deletion in tissues of older humans GA Cortopassi, N Arnheim Nucleic acids research 18 (23), 6927-6933, 1990 | 976 | 1990 |
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. GA Cortopassi, D Shibata, NW Soong, N Arnheim Proceedings of the National Academy of Sciences 89 (16), 7370-7374, 1992 | 843 | 1992 |
A simple method for site-directed mutagenesis using the polymerase chain reaction A Hemsley, N Arnheim, MD Toney, G Cortopassi, DJ Galas Nucleic acids research 17 (16), 6545-6551, 1989 | 821 | 1989 |
Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. AN Murphy, DE Bredesen, G Cortopassi, E Wang, G Fiskum Proceedings of the National Academy of Sciences 93 (18), 9893-9898, 1996 | 520 | 1996 |
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain N Wei Soong, DR Hinton, G Cortopassi, N Arnheim Nature genetics 2 (4), 318-323, 1992 | 512 | 1992 |
A ketogenic diet extends longevity and healthspan in adult mice MN Roberts, MA Wallace, AA Tomilov, Z Zhou, GR Marcotte, D Tran, ... Cell metabolism 26 (3), 539-546. e5, 2017 | 482 | 2017 |
BCL2 translocation frequency rises with age in humans. Y LIu, AM Hernandez, D Shibata, GA Cortopassi Proceedings of the National Academy of Sciences 91 (19), 8910-8914, 1994 | 434 | 1994 |
The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis J Yang, P Cavadini, C Gellera, B Lonnerdal, F Taroni, G Cortopassi Human molecular genetics 8 (3), 425-430, 1999 | 422 | 1999 |
A molecular basis for human hypersensitivity of aminoglyscoside antibiotics T Hutchin, lan Haworth, K Higashi, N Fischel-Ghodsian, M Stoneking, ... Nucleic acids research 21 (18), 4174-4179, 1993 | 335 | 1993 |
Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1α expression W Chowanadisai, KA Bauerly, E Tchaparian, A Wong, GA Cortopassi, ... Journal of Biological Chemistry 285 (1), 142-152, 2010 | 332 | 2010 |
Mitochondria in organismal aging and degeneration GA Cortopassi, A Wong Biochimica et Biophysica Acta (BBA)-Bioenergetics 1410 (2), 183-193, 1999 | 272 | 1999 |
Deleterious mitochondrial DNA mutations accumulate in aging human tissues N Arnheim, G Cortopassi Mutation Research/DNAging 275 (3-6), 157-167, 1992 | 271 | 1992 |
Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c JC Yang, GA Cortopassi Free Radical Biology and Medicine 24 (4), 624-631, 1998 | 264 | 1998 |
A mitochondrial DNA clone is associated with increased risk for Alzheimer disease. T Hutchin, G Cortopassi Proceedings of the National Academy of Sciences 92 (15), 6892-6895, 1995 | 240 | 1995 |
Genetic basis for susceptibility to noise-induced hearing loss in mice RR Davis, JK Newlander, XB Ling, GA Cortopassi, EF Krieg, LC Erway Hearing research 155 (1-2), 82-90, 2001 | 215 | 2001 |
Differentiation-specific effects of LHON mutations introduced into neuronal NT2 cells A Wong, L Cavelier, HE Collins-Schramm, MF Seldin, M McGrogan, ... Human molecular genetics 11 (4), 431-438, 2002 | 212 | 2002 |
OPA 1 Mutation and Late‐Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability L Chen, T Liu, A Tran, X Lu, AA Tomilov, V Davies, G Cortopassi, ... Journal of the American Heart Association 1 (5), e003012, 2012 | 208 | 2012 |
Mitochondria-mediated cell injury KB Wallace, JT Eells, VMC Madeira, G Cortopassi, DP Jones Toxicological Sciences 38 (1), 23-37, 1997 | 184 | 1997 |
Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones Y Shan, E Napoli, G Cortopassi Human molecular genetics 16 (8), 929-941, 2007 | 181 | 2007 |