| Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers M Gu, NY Shao, S Sa, D Li, V Termglinchan, M Ameen, I Karakikes, ... Cell stem cell 20 (4), 490-504. e5, 2017 | 198 | 2017 |
| Inhibition of soluble epoxide hydrolase attenuates high-fat-diet–induced hepatic steatosis by reduced systemic inflammatory status in mice Y Liu, H Dang, D Li, W Pang, BD Hammock, Y Zhu PloS one 7 (6), e39165, 2012 | 136 | 2012 |
| Activation of integrin α5 mediated by flow requires its translocation to membrane lipid rafts in vascular endothelial cells X Sun, Y Fu, M Gu, L Zhang, D Li, H Li, S Chien, JYJ Shyy, Y Zhu Proceedings of the National Academy of Sciences 113 (3), 769-774, 2016 | 109 | 2016 |
| Induced pluripotent stem cell model of pulmonary arterial hypertension reveals novel gene expression and patient specificity S Sa, M Gu, J Chappell, NY Shao, M Ameen, KAT Elliott, D Li, F Grubert, ... American journal of respiratory and critical care medicine 195 (7), 930-941, 2017 | 85 | 2017 |
| Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension PI Chen, A Cao, K Miyagawa, NF Tojais, JK Hennigs, CG Li, NM Sweeney, ... JCI Insight 2 (2), 2017 | 83 | 2017 |
| PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis CG Li, C Mahon, NM Sweeney, E Verschueren, V Kantamani, D Li, ... Cell reports 26 (5), 1333-1343. e7, 2019 | 68 | 2019 |
| Metabonomic changes associated with atherosclerosis progression for LDLR–/–mice D Li, L Zhang, F Dong, Y Liu, N Li, H Li, H Lei, F Hao, Y Wang, Y Zhu, ... Journal of proteome research 14 (5), 2237-2254, 2015 | 64 | 2015 |
| Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension A Reyes-Palomares, M Gu, F Grubert, I Berest, S Sa, M Kasowski, ... Nature Communications 11 (1), 1673, 2020 | 63 | 2020 |
| Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ... Circulation 136 (20), 1920-1935, 2017 | 54 | 2017 |
| ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension D Li, NY Shao, JR Moonen, Z Zhao, M Shi, S Otsuki, L Wang, T Nguyen, ... Circulation 143 (21), 2074-2090, 2021 | 43 | 2021 |
| KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress JR Moonen, J Chappell, M Shi, T Shinohara, D Li, MR Mumbach, F Zhang, ... Nature Communications 13 (1), 4941, 2022 | 35 | 2022 |
| Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr−/− mice D Li, Y Liu, X Zhang, H Lv, W Pang, X Sun, LM Gan, BD Hammock, D Ai, ... Journal of Molecular and Cellular Cardiology 98, 128-137, 2016 | 35 | 2016 |
| Metabolic profiling of murine plasma reveals eicosapentaenoic acid metabolites protecting against endothelial activation and atherosclerosis Y Liu, X Fang, X Zhang, J Huang, J He, L Peng, C Ye, Y Wang, F Xue, ... British journal of pharmacology 175 (8), 1190-1204, 2018 | 28 | 2018 |
| Monocyte-released HERV-K dUTPase engages TLR4 and MCAM causing endothelial mesenchymal transition S Otsuki, T Saito, S Taylor, D Li, JR Moonen, DP Marciano, RL Harper, ... JCI insight 6 (15), 2021 | 22 | 2021 |
| Dysregulated Smooth Muscle Cell BMPR2–ARRB2 Axis Causes Pulmonary Hypertension L Wang, JR Moonen, A Cao, S Isobe, CG Li, NF Tojais, S Taylor, ... Circulation Research 132 (5), 545-564, 2023 | 9 | 2023 |
| The TBK1/IKKε inhibitor amlexanox improves dyslipidemia and prevents atherosclerosis P Zhao, X Sun, Z Liao, H Yu, D Li, Z Shen, CK Glass, JL Witztum, ... JCI insight 7 (17), 2022 | 2 | 2022 |
| Selective ITK blockade induces antitumor responses and enhances efficacy to immune checkpoint inhibitors in preclinical models LY Hsu, R Pawar, D Li, P Ghosh, K Nguyen, C Williams, Y Song, N Ding, ... Cancer Research 83 (7_Supplement), 1813-1813, 2023 | | 2023 |
| Soquelitinb, A selective inhibitor of interleukin-2-inducible kinase (ITK), is active in several murine models of T cell-mediated inflammatory disease LY Hsu, JT Rosenbaum, S Lindner, Y Allanore, A Cauvet, RD Pawar, D Li, ... bioRxiv, 2023.10. 27.564296, 2023 | | 2023 |
| KLF and AP1 Having Opposing Roles in Regulating Chromatin Accessibility and the Endothelial Enhancer Landscape Under Laminar vs. Disturbed Shear Stress JR Moonen, J Chappell, D Li, M Shi, A Cao, S Taylor, Z Zhao, L Wang, ... Circulation. 2018;138:A16925, 2018 | | 2018 |
| ALDH1A3 Induces NFY to Coordinate Transcription of Cell Cycle and Metabolic Genes Necessary for Smooth Muscle Proliferation in Pulmonary Hypertension D Li, N Shao, K Contrepois, S Taylor, S Otsuki, L Wang, M Rabinovitch Circulation. 2018;138:A17192, 2018 | | 2018 |
