Hugues Aschard
Hugues Aschard
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Effect of 17q21 variants and smoking exposure in early-onset asthma
E Bouzigon, E Corda, H Aschard, MH Dizier, A Boland, J Bousquet, ...
New England journal of medicine 359 (19), 1985-1994, 2008
Fungal microbiota dysbiosis in IBD
H Sokol, V Leducq, H Aschard, HP Pham, S Jegou, C Landman, D Cohen, ...
Gut 66 (6), 1039-1048, 2017
Adjusting for heritable covariates can bias effect estimates in genome-wide association studies
H Aschard, BJ Vilhjálmsson, AD Joshi, AL Price, P Kraft
The American Journal of Human Genetics 96 (2), 329-339, 2015
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function
DB Hancock, MS Artigas, SA Gharib, A Henry, A Manichaikul, ...
PLoS Genet 8 (12), e1003098, 2012
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
JNC Bailey, SJ Loomis, JH Kang, RR Allingham, P Gharahkhani, CC Khor, ...
Nature genetics 48 (2), 189-194, 2016
Challenges and opportunities in genome-wide environmental interaction (GWEI) studies
H Aschard, S Lutz, B Maus, EJ Duell, TE Fingerlin, N Chatterjee, P Kraft, ...
Human genetics 131 (10), 1591-1613, 2012
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
X Jiang, PF O’Reilly, H Aschard, YH Hsu, JB Richards, J Dupuis, ...
Nature communications 9 (1), 1-12, 2018
Maximizing the power of principal-component analysis of correlated phenotypes in genome-wide association studies
H Aschard, BJ Vilhjálmsson, N Greliche, PE Morange, DA Trégouët, ...
The American Journal of Human Genetics 94 (5), 662-676, 2014
A comprehensive analysis of in vitro and in vivo genetic fitness of Pseudomonas aeruginosa using high-throughput sequencing of transposon libraries
D Skurnik, D Roux, H Aschard, V Cattoir, D Yoder-Himes, S Lory, GB Pier
PLoS Pathog 9 (9), e1003582, 2013
Inclusion of gene-gene and gene-environment interactions unlikely to dramatically improve risk prediction for complex diseases
H Aschard, J Chen, MC Cornelis, LB Chibnik, EW Karlson, P Kraft
The American Journal of Human Genetics 90 (6), 962-972, 2012
Fitness cost of antibiotic susceptibility during bacterial infection
D Roux, O Danilchanka, T Guillard, V Cattoir, H Aschard, Y Fu, ...
Science translational medicine 7 (297), 297ra114-297ra114, 2015
Enhanced in vivo fitness of carbapenem-resistant oprD mutants of Pseudomonas aeruginosa revealed through high-throughput sequencing
D Skurnik, D Roux, V Cattoir, O Danilchanka, X Lu, DR Yoder-Himes, ...
Proceedings of the National Academy of Sciences 110 (51), 20747-20752, 2013
17q21 variants modify the association between early respiratory infections and asthma
LAM Smit, E Bouzigon, I Pin, V Siroux, F Monier, H Aschard, J Bousquet, ...
European Respiratory Journal 36 (1), 57-64, 2010
Genome-wide meta-analysis of joint tests for genetic and gene-environment interaction effects
H Aschard, DB Hancock, SJ London, P Kraft
Human heredity 70 (4), 292-300, 2010
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges
B Piasecka, D Duffy, A Urrutia, H Quach, E Patin, C Posseme, J Bergstedt, ...
Proceedings of the National Academy of Sciences 115 (3), E488-E497, 2018
A perspective on interaction effects in genetic association studies
H Aschard
Genetic epidemiology 40 (8), 678-688, 2016
Genomewide meta‐analysis identifies loci associated with IGF‐I and IGFBP‐3 levels with impact on age‐related traits
A Teumer, Q Qi, M Nethander, H Aschard, S Bandinelli, M Beekman, ...
Aging cell 15 (5), 811-824, 2016
Current challenges and new opportunities for gene-environment interaction studies of complex diseases
K McAllister, LE Mechanic, C Amos, H Aschard, IA Blair, N Chatterjee, ...
American journal of epidemiology 186 (7), 753-761, 2017
A large-scale multi-ancestry genome-wide study accounting for smoking behavior identifies multiple significant loci for blood pressure
YJ Sung, TW Winkler, L de Las Fuentes, AR Bentley, MR Brown, AT Kraja, ...
The American Journal of Human Genetics 102 (3), 375-400, 2018
Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr
F Privé, H Aschard, A Ziyatdinov, MGB Blum
Bioinformatics 34 (16), 2781-2787, 2018
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