| The multifactorial nature of Alzheimer’s disease for developing potential therapeutics M Carmo Carreiras, E Mendes, M Jesus Perry, A Paula Francisco, ... Current topics in medicinal chemistry 13 (15), 1745-1770, 2013 | 249 | 2013 |
| Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-β-induced neurotoxicity D Silva, M Chioua, A Samadi, P Agostinho, P Garcao, R Lajarín-Cuesta, ... ACS Chemical Neuroscience 4 (4), 547-565, 2013 | 64 | 2013 |
| Synthesis and pharmacological assessment of diversely substituted pyrazolo [3, 4-b] quinoline, and benzo [b] pyrazolo [4, 3-g][1, 8] naphthyridine derivatives D Silva, M Chioua, A Samadi, MC Carreiras, ML Jimeno, E Mendes, ... European journal of medicinal chemistry 46 (9), 4676-4681, 2011 | 64 | 2011 |
| Mid-infrared spectroscopy as a valuable tool to tackle food analysis: A literature review on coffee, dairies, honey, olive oil and wine E Mendes, N Duarte Foods 10 (2), 477, 2021 | 62 | 2021 |
| Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives H Brito, AC Martins, J Lavrado, E Mendes, AP Francisco, SA Santos, ... PLoS One 10 (5), e0126891, 2015 | 59 | 2015 |
| Design and discovery of mushroom tyrosinase inhibitors and their therapeutic applications E Mendes, MJ Perry, AP Francisco Expert opinion on drug discovery 9 (5), 533-554, 2014 | 54 | 2014 |
| Acyloxymethyl as a drug protecting group: Part 4. The hydrolysis of tertiary amidomethyl ester prodrugs of carboxylic acid agents J Iley, R Moreira, T Calheiros, E Mendes Pharmaceutical research 14 (11), 1634-1639, 1997 | 35 | 1997 |
| Dopamine-and tyramine-based derivatives of triazenes: Activation by tyrosinase and implications for prodrug design MJ Perry, E Mendes, AL Simplício, A Coelho, RV Soares, J Iley, R Moreira, ... European journal of medicinal chemistry 44 (8), 3228-3234, 2009 | 33 | 2009 |
| A new direct synthesis of tertiary N-acyloxymethylamide prodrugs of carboxylic acid drugs R Moreira, E Mendes, T Calheiros, MJ Bacelo, J Iley Tetrahedron letters 35 (38), 7107-7110, 1994 | 32 | 1994 |
| Diterpenoids from Salvia candelabrum E Mendes, JL Marco, B Rodríguez, ML Jimeno, AM Lobo, S Prabhakar Phytochemistry 28 (6), 1685-1690, 1989 | 32 | 1989 |
| Acyloxymethyl as a Drug Protecting Group. Part 3. Tertiary O-Amidomethyl Esters of Penicillin G: Chemical Hydrolysis and Anti-Bacterial Activity R Moreira, T Calheiros, J Cabrita, E Mendes, M Pimentel, J Iley Pharmaceutical research 13, 70-75, 1996 | 28 | 1996 |
| Major achievements in the design of quadruplex-interactive small molecules E Mendes, IM Aljnadi, B Bahls, BL Victor, A Paulo Pharmaceuticals 15 (3), 300, 2022 | 27 | 2022 |
| Anticancer triazenes: from bioprecursors to hybrid molecules AP Francisco, E Mendes, AR Santos, MJ Perry Current Pharmaceutical Design 25 (14), 1623-1642, 2019 | 27 | 2019 |
| The selective cytotoxicity of new triazene compounds to human melanoma cells A Sousa, F Santos, MM Gaspar, S Calado, JD Pereira, E Mendes, ... Bioorganic & Medicinal Chemistry 25 (15), 3900-3910, 2017 | 25 | 2017 |
| Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: Role of Asn181 and Ile335 validated by spectroscopic and … J Juárez-Jiménez, E Mendes, C Galdeano, C Martins, DB Silva, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (2), 389-397, 2014 | 23 | 2014 |
| Synthesis and evaluation of N-acylamino acids derivatives of triazenes. Activation by tyrosinase in human melanoma cell lines AS Monteiro, J Almeida, G Cabral, P Severino, PA Videira, A Sousa, ... European Journal of Medicinal Chemistry 70, 1-9, 2013 | 23 | 2013 |
| Alkylating agents AP Francisco, MJ Perry, R Moreira, E Mendes Anticancer therapeutics, 133-158, 2008 | 22 | 2008 |
| Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac: Suppressing the rearrangement pathway in aqueous media L Ribeiro, N Silva, J Iley, J Rautio, T Järvinen, H Mota‐Filipe, R Moreira, ... Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2007 | 21 | 2007 |
| Development of triazene prodrugs for ADEPT strategy: New insights into drug delivery system based on carboxypeptidase G2 activation V Capucha, E Mendes, AP Francisco, MJ Perry Bioorganic & medicinal chemistry letters 22 (22), 6903-6908, 2012 | 19 | 2012 |
| Synthesis, stability and in vitro dermal evaluation of aminocarbonyloxymethyl esters as prodrugs of carboxylic acid agents E Mendes, T Furtado, J Neres, J Iley, T Jarvinen, J Rautio, R Moreira Bioorganic & medicinal chemistry 10 (3), 809-816, 2002 | 19 | 2002 |
