| International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1,-2, and-3: pharmacology and pathophysiological functions LA Stoddart, NJ Smith, G Milligan Pharmacological reviews 60 (4), 405-417, 2008 | 297 | 2008 |
| Allostery at G protein-coupled receptor homo-and heteromers: uncharted pharmacological landscapes NJ Smith, G Milligan Pharmacological reviews 62 (4), 701-725, 2010 | 258 | 2010 |
| Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements R Schröder, N Janssen, J Schmidt, A Kebig, N Merten, S Hennen, ... Nature biotechnology 28 (9), 943-949, 2010 | 247 | 2010 |
| Allosteric modulation of heterodimeric G-protein-coupled receptors G Milligan, NJ Smith Trends in pharmacological sciences 28 (12), 615-620, 2007 | 174 | 2007 |
| Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3 J Schmidt, NJ Smith, E Christiansen, IG Tikhonova, M Grundmann, ... Journal of Biological Chemistry 286 (12), 10628-10640, 2011 | 105 | 2011 |
| Angiotensin1‐9 antagonises pro‐hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor M Flores‐Muñoz, NJ Smith, C Haggerty, G Milligan, SA Nicklin The journal of Physiology 589 (4), 939-951, 2011 | 89 | 2011 |
| The action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1 NJ Smith, LA Stoddart, NM Devine, L Jenkins, G Milligan Journal of Biological Chemistry 284 (26), 17527-17539, 2009 | 85 | 2009 |
| Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short … LA Stoddart, NJ Smith, L Jenkins, AJ Brown, G Milligan Journal of Biological Chemistry 283 (47), 32913-32924, 2008 | 84 | 2008 |
| Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13 L Jenkins, J Brea, NJ Smith, BD Hudson, G Reilly, NJ Bryant, M Castro, ... Biochemical Journal 432 (3), 451-459, 2010 | 82 | 2010 |
| When simple agonism is not enough: emerging modalities of GPCR ligands NJ Smith, KA Bennett, G Milligan Molecular and cellular endocrinology 331 (2), 241-247, 2011 | 65 | 2011 |
| Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator NJ Smith, RJ Ward, LA Stoddart, BD Hudson, E Kostenis, T Ulven, ... Molecular pharmacology 80 (1), 163-173, 2011 | 63 | 2011 |
| What’s new in the renin-angiotensin system? NJ Smith, HW Chan, JE Osborne, WG Thomas, RD Hannan Cellular and Molecular Life Sciences CMLS 61 (21), 2695-2703, 2004 | 54 | 2004 |
| Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes JW McNamara, A Li, NJ Smith, S Lal, RM Graham, KB Kooiker, ... Journal of molecular and cellular cardiology 94, 65-71, 2016 | 52 | 2016 |
| Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3 G Milligan, LA Stoddart, NJ Smith British journal of pharmacology 158 (1), 146-153, 2009 | 50 | 2009 |
| Signal switching, crosstalk, and arrestin scaffolds: novel G protein–coupled receptor signaling in cardiovascular disease NJ Smith, LM Luttrell Hypertension 48 (2), 173-179, 2006 | 49 | 2006 |
| Identifying ligands at orphan GPCRs: current status using structure‐based approaches T Ngo, I Kufareva, JLJ Coleman, RM Graham, R Abagyan, NJ Smith British journal of pharmacology 173 (20), 2934-2951, 2016 | 48 | 2016 |
| Experimental challenges to targeting poorly characterized GPCRs: uncovering the therapeutic potential for free fatty acid receptors BD Hudson, NJ Smith, G Milligan Advances in pharmacology 62, 175-218, 2011 | 43 | 2011 |
| Tackling the EGFR in pathological tissue remodelling HW Chan, NJ Smith, RD Hannan, WG Thomas Pulmonary pharmacology & therapeutics 19 (1), 74-78, 2006 | 37 | 2006 |
| Orphan receptor ligand discovery by pickpocketing pharmacological neighbors T Ngo, AV Ilatovskiy, AG Stewart, JLJ Coleman, FM McRobb, RP Riek, ... Nature chemical biology 13 (2), 235-242, 2017 | 36 | 2017 |
| A molecular mechanism for sequential activation of a G protein-coupled receptor M Grundmann, IG Tikhonova, BD Hudson, NJ Smith, K Mohr, T Ulven, ... Cell chemical biology 23 (3), 392-403, 2016 | 28 | 2016 |
