|p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex|
L Nguyen, A Besson, JIT Heng, C Schuurmans, L Teboul, C Parras, ...
Genes & development 20 (11), 1511-1524, 2006
|Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex|
R Hand, D Bortone, P Mattar, L Nguyen, JIT Heng, S Guerrier, E Boutt, ...
Neuron 48 (1), 45-62, 2005
|The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein|
X Zhao, JIT Heng, D Guardavaccaro, R Jiang, M Pagano, F Guillemot, ...
Nature cell biology 10 (6), 643-653, 2008
|Neurogenin 2 controls cortical neuron migration through regulation of Rnd2|
JIT Heng, L Nguyen, DS Castro, C Zimmer, H Wildner, O Armant, ...
Nature 455 (7209), 114-118, 2008
|Coupling of cell migration with neurogenesis by proneural bHLH factors|
W Ge, F He, KJ Kim, B Blanchi, V Coskun, L Nguyen, X Wu, J Zhao, ...
Proceedings of the National Academy of Sciences 103 (5), 1319-1324, 2006
|Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling|
E Pacary, J Heng, R Azzarelli, P Riou, D Castro, M Lebel-Potter, C Parras, ...
Neuron 69 (6), 1069-1084, 2011
|Pleiotropic effects of GLP-1 and analogs on cell signaling, metabolism, and function|
J Rowlands, J Heng, P Newsholme, R Carlessi
Frontiers in endocrinology 9, 672, 2018
|Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities|
M Breuss, JIT Heng, K Poirier, G Tian, XH Jaglin, Z Qu, A Braun, T Gstrein, ...
Cell reports 2 (6), 1554-1562, 2012
|Familial cortical dysplasia caused by mutation in the mammalian target of rapamycin regulator NPRL3|
JC Sim, T Scerri, M Fanjul‐Fernández, JR Riseley, G Gillies, K Pope, ...
Annals of neurology 79 (1), 132-137, 2016
|Molecular layers underlying cytoskeletal remodelling during cortical development|
JIT Heng, A Chariot, L Nguyen
Trends in neurosciences 33 (1), 38-47, 2010
|Neurotransmitters regulate cell migration in the telencephalon|
JIT Heng, G Moonen, L Nguyen
European Journal of Neuroscience 26 (3), 537-546, 2007
|WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression|
MA Bogoyevitch, YYC Yeap, Z Qu, KR Ngoei, YY Yip, TT Zhao, JI Heng, ...
Journal of cell science 125 (21), 5096-5109, 2012
|RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex|
C Ohtaka-Maruyama, S Hirai, A Miwa, JIT Heng, H Shitara, R Ishii, C Taya, ...
Cell reports 3 (2), 458-471, 2013
|COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression|
C Alfano, L Viola, JIT Heng, M Pirozzi, M Clarkson, G Flore, A De Maio, ...
Development 138 (21), 4685-4697, 2011
|The Zinc Finger Transcription Factor RP58 Negatively Regulates Rnd2 for the Control of Neuronal Migration During Cerebral Cortical Development|
JIT Heng, Z Qu, C Ohtaka-Maruyama, H Okado, M Kasai, D Castro, ...
Cerebral Cortex 25 (3), 806-816, 2015
|Mutations of vasopressin receptor 2 including novel L312S have differential effects on trafficking|
A Tiulpakov, CW White, RS Abhayawardana, HB See, AS Chan, ...
Molecular endocrinology 30 (8), 889-904, 2016
|Molecular mechanisms of projection neuron production and maturation in the developing cerebral cortex|
Y Mérot, S Rétaux, JIT Heng
Seminars in cell & developmental biology 20 (6), 726-734, 2009
|14-3-3ζ deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disorders|
X Xu, EJ Jaehne, Z Greenberg, P McCarthy, E Saleh, CL Parish, ...
Scientific Reports 5 (1), 12434, 2015
|TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons|
L Ngo, M Haas, Z Qu, SS Li, J Zenker, KSL Teng, JM Gunnersen, ...
Human molecular genetics 23 (19), 5147-5158, 2014
|Infantile neurodegenerative disorder associated with mutations in TBCD, an essential gene in the tubulin heterodimer assembly pathway|
S Edvardson, G Tian, H Cullen, H Vanyai, L Ngo, S Bhat, A Aran, ...
Human molecular genetics 25 (21), 4635-4648, 2016