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Nicholas Hum
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Single-cell transcriptomic analysis of tumor-derived fibroblasts and normal tissue-resident fibroblasts reveals fibroblast heterogeneity in breast cancer
A Sebastian, NR Hum, KA Martin, SF Gilmore, I Peran, SW Byers, ...
Cancers 12 (5), 1307, 2020
1742020
Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model
CS Yee, LQ Xie, S Hatsell, N Hum, D Murugesh, AN Economides, ...
Bone 82, 122-134, 2016
802016
SOST/Sclerostin improves posttraumatic osteoarthritis and inhibits MMP2/3 expression after injury
JC Chang, BA Christiansen, DK Murugesh, A Sebastian, NR Hum, ...
Journal of Bone and Mineral Research 33 (6), 1105-1113, 2018
582018
Single-cell RNA-seq reveals transcriptomic heterogeneity and post-traumatic osteoarthritis-associated early molecular changes in mouse articular chondrocytes
A Sebastian, JL McCool, NR Hum, DK Murugesh, SP Wilson, ...
Cells 10 (6), 1462, 2021
542021
Cadherin 11 promotes immunosuppression and extracellular matrix deposition to support growth of pancreatic tumors and resistance to gemcitabine in mice
I Peran, S Dakshanamurthy, MD McCoy, A Mavropoulos, B Allo, ...
Gastroenterology 160 (4), 1359-1372. e13, 2021
522021
Conditional Deletion of Sost in MSC‐Derived Lineages Identifies Specific Cell‐Type Contributions to Bone Mass and B‐Cell Development
CS Yee, JO Manilay, JC Chang, NR Hum, DK Murugesh, J Bajwa, ...
Journal of Bone and Mineral Research 33 (10), 1748-1759, 2018
452018
Cancer–Osteoblast Interaction Reduces Sost Expression in Osteoblasts and Up-Regulates lncRNA MALAT1 in Prostate Cancer
A Sebastian, NR Hum, BD Hudson, GG Loots
Microarrays 4 (4), 503-519, 2015
412015
Electric fields at breast cancer and cancer cell collective galvanotaxis
K Zhu, NR Hum, B Reid, Q Sun, GG Loots, M Zhao
Scientific reports 10 (1), 8712, 2020
382020
Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells
NM Collette, CS Yee, NR Hum, DK Murugesh, BA Christiansen, LQ Xie, ...
Bone 88, 20-30, 2016
382016
SOST inhibits prostate cancer invasion
BD Hudson, NR Hum, CB Thomas, A Kohlgruber, A Sebastian, ...
PLoS One 10 (11), e0142058, 2015
382015
LPS‐induced inflammation prior to injury exacerbates the development of post‐traumatic osteoarthritis in mice
ME Mendez, A Sebastian, DK Murugesh, NR Hum, JL McCool, AW Hsia, ...
Journal of Bone and Mineral Research 35 (11), 2229-2241, 2020
372020
Global gene expression analysis identifies age-related differences in knee joint transcriptome during the development of post-traumatic osteoarthritis in mice
A Sebastian, DK Murugesh, ME Mendez, NR Hum, ND Rios-Arce, ...
International journal of molecular sciences 21 (1), 364, 2020
372020
Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates
JN Harvestine, T Gonzalez-Fernandez, A Sebastian, NR Hum, ...
Science advances 6 (7), eaay2387, 2020
362020
Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts
A Sebastian, NR Hum, DK Murugesh, S Hatsell, AN Economides, ...
PLoS One 12 (11), e0188264, 2017
342017
Functional and transcriptional characterization of complex neuronal co-cultures
HA Enright, D Lam, A Sebastian, AP Sales, J Cadena, NR Hum, ...
Scientific reports 10 (1), 11007, 2020
292020
Comparative molecular analysis of cancer behavior cultured in vitro, in vivo, and ex vivo
NR Hum, A Sebastian, SF Gilmore, W He, KA Martin, A Hinckley, ...
Cancers 12 (3), 690, 2020
262020
Maternal exposure to an environmentally relevant dose of triclocarban results in perinatal exposure and potential alterations in offspring development in the mouse model
HA Enright, MJS Falso, MA Malfatti, V Lao, EA Kuhn, N Hum, Y Shi, ...
PLoS One 12 (8), e0181996, 2017
252017
Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis
A Sebastian, NR Hum, JL McCool, SP Wilson, DK Murugesh, KA Martin, ...
Frontiers in immunology 13, 938075, 2022
242022
Manipulation of the gut microbiome alters acetaminophen biodisposition in mice
MA Malfatti, EA Kuhn, DK Murugesh, ME Mendez, N Hum, JB Thissen, ...
Scientific reports 10 (1), 4571, 2020
242020
Antibiotic treatment prior to injury improves post-traumatic osteoarthritis outcomes in mice
ME Mendez, DK Murugesh, A Sebastian, NR Hum, SA McCloy, EA Kuhn, ...
International journal of molecular sciences 21 (17), 6424, 2020
222020
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