Aleksey Ustyugov
Aleksey Ustyugov
Research Associate, Institute of Physiologically Active Compounds Russian Academy of Sciences
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Drugs in clinical trials for Alzheimer's disease: the major trends
SO Bachurin, EV Bovina, AA Ustyugov
Medicinal research reviews 37 (5), 1186-1225, 2017
Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice
TA Shelkovnikova, OM Peters, AV Deykin, N Connor-Robson, ...
Journal of Biological Chemistry 288 (35), 25266-25274, 2013
Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice
OM Peters, N Connor-Robson, VB Sokolov, AY Aksinenko, MS Kukharsky, ...
Journal of Alzheimer's Disease 33 (4), 1041-1049, 2013
Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice
SO Bachurin, TA Shelkovnikova, AA Ustyugov, O Peters, I Khritankova, ...
Neurotoxicity research 22 (1), 33-42, 2012
Novel sites of neuroprotective action of Dimebon (latrepirdine)
A Ustyugov, E Shevtsova, S Bachurin
Molecular neurobiology 52 (2), 970-978, 2015
Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds
SO Bachurin, AA Ustyugov, O Peters, TA Shelkovnikova, VL Buchman, ...
Doklady. Biochemistry and biophysics 428 (1), 235, 2009
9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment
GF Makhaeva, SV Lushchekina, NP Boltneva, OG Serebryakova, ...
Bioorganic & medicinal chemistry 25 (21), 5981-5994, 2017
Hsp27 is persistently expressed in zebrafish skeletal and cardiac muscle tissues but dispensable for their morphogenesis
NR Tucker, A Ustyugov, AL Bryantsev, ME Konkel, EA Shelden
Cell Stress and Chaperones 14 (5), 521-533, 2009
Блокада нейродегенеративных процессов, вызванных протеинопатией, как новый механизм действия нейропротекторных и когнитивно-стимулирующих препаратов
СО Бачурин, АА Устюгов, О Петерс, ТА Шелковникова, ВЛ Бухман, ...
Доклады Академии Наук 428 (2), 262-265, 2009
A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression
N Ninkina, N Connor-Robson, AA Ustyugov, TV Tarasova, ...
Scientific reports 5 (1), 1-6, 2015
C9ORF72 hexanucleotide repeat expansion in ALS patients from the Central European Russia population
NY Abramycheva, EV Lysogorskaia, MS Stepanova, MN Zakharova, ...
Neurobiology of aging 36 (10), 2908. e5-2908. e9, 2015
Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif
HK Robinson, AV Deykin, EV Bronovitsky, RK Ovchinnikov, AA Ustyugov, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16 (5-6), 402-409, 2015
TA Shelkovni kova, VL Bukhman, NN Ninkina
SO Bachurin, AA Ustyugov, O Peters
Dokl. Akad. Nauk 428, 262, 2009
Dimebon reduces the levels of aggregated amyloidogenic protein forms in detergent-insoluble fractions in vivo
AA Ustyugov, TA Shelkovnikova, VS Kokhan, IV Khritankova, O Peters, ...
Bulletin of experimental biology and medicine 152 (6), 731, 2012
Новые аспекты патогенеза бокового амиотрофического склероза
ВИ Скворцова, СО Бачурин, ОД Разинская, АП Смирнов, ...
Журнал неврологии и психиатрии им. СС Корсакова 111 (2), 4-9, 2011
Dimebon does not ameliorate pathological changes caused by expression of truncated (1–120) human alpha-synuclein in dopaminergic neurons of transgenic mice
TA Shelkovnikova, AA Ustyugov, S Millership, O Peters, O Anichtchik, ...
Neurodegenerative Diseases 8 (6), 430-437, 2011
Chikungunya virus inhibition by synthetic coumarin–guanosine conjugates
JR Hwu, WC Huang, SY Lin, KT Tan, YC Hu, FK Shieh, SO Bachurin, ...
European journal of medicinal chemistry 166, 136-143, 2019
Alzheimer's Disease–Future Therapy Based on Dendrimers
G Aliev, GM Ashraf, VV Tarasov, VN Chubarev, J Leszek, K Gasiorowski, ...
Current neuropharmacology 17 (3), 288-294, 2019
Applications of multi-target computer-aided methodologies in molecular design of CNS drugs
OA Raevsky, A Mukhametov, VY Grigorev, A Ustyugov, SC Tsay, ...
Current medicinal chemistry 25 (39), 5293-5314, 2018
The Y-box binding protein 1 suppresses Alzheimer’s disease progression in two animal models
NV Bobkova, DN Lyabin, NI Medvinskaya, AN Samokhin, PV Nekrasov, ...
PloS one 10 (9), e0138867, 2015
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