Follow
John D Lee
Title
Cited by
Cited by
Year
The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
7382019
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
4422021
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins
V Deora, JD Lee, EA Albornoz, L McAlary, CJ Jagaraj, AAB Robertson, ...
Glia 68 (2), 407-421, 2020
1562020
The complement receptor C5aR2: a powerful modulator of innate and adaptive immunity
XX Li, JD Lee, C Kemper, TM Woodruff
The Journal of Immunology 202 (12), 3339-3348, 2019
1162019
Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis
MJ Fogarty, PM Klenowski, JD Lee, JR Drieberg-Thompson, SE Bartlett, ...
Scientific reports 6 (1), 37968, 2016
912016
Complement dysregulation in the central nervous system during development and disease
JD Lee, LG Coulthard, TM Woodruff
Seminars in Immunology 45, 101340, 2019
892019
Pharmacological inhibition of complement C5a‐C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral …
JD Lee, V Kumar, JNT Fung, MJ Ruitenberg, PG Noakes, TM Woodruff
British journal of pharmacology 174 (8), 689-699, 2017
892017
Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis
JY Lee, JD Lee, S Phipps, PG Noakes, TM Woodruff
Journal of neuroinflammation 12, 1-9, 2015
862015
Dysregulation of the complement cascade in the hSOD1G93Atransgenic mouse model of amyotrophic lateral sclerosis
JD Lee, NA Kamaruzaman, JNT Fung, SM Taylor, BJ Turner, JD Atkin, ...
Journal of neuroinflammation 10, 1-15, 2013
862013
Complement C5aR1 signaling promotes polarization and proliferation of embryonic neural progenitor cells through PKCζ
LG Coulthard, OA Hawksworth, R Li, A Balachandran, JD Lee, ...
Journal of Neuroscience 37 (22), 5395-5407, 2017
742017
Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions
FH Brennan, JD Lee, MJ Ruitenberg, TM Woodruff
Seminars in Immunology 28 (3), 292-308, 2016
722016
Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
S Pandey, P Kumari, M Baidya, R Kise, Y Cao, H Dwivedi-Agnihotri, ...
Molecular cell 81 (22), 4605-4621. e11, 2021
712021
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ...
Molecular psychiatry 28 (7), 2878-2893, 2023
692023
The peripheral immune system and amyotrophic lateral sclerosis
PA McCombe, JD Lee, TM Woodruff, RD Henderson
Frontiers in neurology 11, 499577, 2020
682020
Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in mice
V Kumar, JD Lee, RJ Clark, PG Noakes, SM Taylor, TM Woodruff
ACS omega 5 (5), 2345-2354, 2020
672020
Defects in synaptic transmission at the neuromuscular junction precede motor deficits in a TDP‐43Q331K transgenic mouse model of amyotrophic lateral sclerosis
KK Chand, KM Lee, JD Lee, H Qiu, EF Willis, NA Lavidis, MA Hilliard, ...
The FASEB Journal 32 (5), 2676-2689, 2018
642018
Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function
XX Li, JD Lee, NL Massey, C Guan, AAB Robertson, RJ Clark, ...
Biochemical pharmacology 180, 114156, 2020
512020
Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis
HA Wang, JD Lee, KM Lee, TM Woodruff, PG Noakes
Skeletal muscle 7, 1-11, 2017
502017
Role for terminal complement activation in amyotrophic lateral sclerosis disease progression
TM Woodruff, JD Lee, PG Noakes
Proceedings of the National Academy of Sciences 111 (1), E3-E4, 2014
502014
Complement components are upregulated and correlate with disease progression in the TDP-43Q331K mouse model of amyotrophic lateral sclerosis
JD Lee, SC Levin, EF Willis, R Li, TM Woodruff, PG Noakes
Journal of neuroinflammation 15, 1-13, 2018
492018
The system can't perform the operation now. Try again later.
Articles 1–20