Douglas Fairlie
Douglas Fairlie
Olivia Newton-John Cancer Research Institute and La Trobe University
Verified email at - Homepage
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
SN Willis, JI Fletcher, T Kaufmann, MF van Delft, L Chen, PE Czabotar, ...
Science 315 (5813), 856-859, 2007
MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily
MR Bootcov, AR Bauskin, SM Valenzuela, AG Moore, M Bansal, XY He, ...
Proceedings of the National Academy of Sciences 94 (21), 11514-11519, 1997
Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1
H Johnen, S Lin, T Kuffner, DA Brown, VWW Tsai, AR Bauskin, L Wu, ...
Nature medicine 13 (11), 1333-1340, 2007
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis
PE Czabotar, D Westphal, G Dewson, S Ma, C Hockings, WD Fairlie, ...
Cell 152 (3), 519-531, 2013
Structural insights into the degradation of Mcl-1 induced by BH3 domains
PE Czabotar, EF Lee, MF van Delft, CL Day, BJ Smith, DCS Huang, ...
Proceedings of the National Academy of Sciences 104 (15), 6217-6222, 2007
Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia
SP Glaser, EF Lee, E Trounson, P Bouillet, A Wei, WD Fairlie, DJ Izon, ...
Genes & development 26 (2), 120-125, 2012
Membrane-bound Fas ligand only is essential for Fas-induced apoptosis
LA O’Reilly, L Tai, L Lee, EA Kruse, S Grabow, WD Fairlie, NM Haynes, ...
Nature 461 (7264), 659-663, 2009
Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study
DA Brown, SN Breit, J Buring, WD Fairlie, AR Bauskin, T Liu, PM Ridker
The Lancet 359 (9324), 2159-2163, 2002
MIC‐1 is a novel TGF‐β superfamily cytokine associated with macrophage activation
WD Fairlie, AG Moore, AR Bauskin, PK Russell, HP Zhang, SN Breit
Journal of leukocyte biology 65 (1), 2-5, 1999
Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family
EF Lee, PE Czabotar, BJ Smith, K Deshayes, K Zobel, PM Colman, ...
Cell Death & Differentiation 14 (9), 1711-1713, 2007
Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands
M Kvansakul, H Yang, WD Fairlie, PE Czabotar, SF Fischer, MA Perugini, ...
Cell Death & Differentiation 15 (10), 1564-1571, 2008
The transforming growth factor-β superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women
AG Moore, DA Brown, WD Fairlie, AR Bauskin, PK Brown, MLC Munier, ...
The Journal of Clinical Endocrinology & Metabolism 85 (12), 4781-4788, 2000
Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-Å resolution
SJ Harrop, MZ DeMaere, WD Fairlie, T Reztsova, SM Valenzuela, ...
Journal of Biological Chemistry 276 (48), 44993-45000, 2001
The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition
DR Littler, SJ Harrop, WD Fairlie, LJ Brown, GJ Pankhurst, S Pankhurst, ...
Journal of Biological Chemistry 279 (10), 9298-9305, 2004
Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1
CL Day, C Smits, FC Fan, EF Lee, WD Fairlie, MG Hinds
Journal of molecular biology 380 (5), 958-971, 2008
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins
D Mérino, M Giam, PD Hughes, OM Siggs, K Heger, LA O'Reilly, ...
Journal of cell biology 186 (3), 355-362, 2009
Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax
JI Fletcher, S Meusburger, CJ Hawkins, DT Riglar, EF Lee, WD Fairlie, ...
Proceedings of the National Academy of Sciences 105 (47), 18081-18087, 2008
Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1
M Albertoni, PH Shaw, M Nozaki, S Godard, M Tenan, MF Hamou, ...
Oncogene 21 (27), 4212-4219, 2002
Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells
D Mérino, SL Khaw, SP Glaser, DJ Anderson, LD Belmont, C Wong, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5807-5816, 2012
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