| Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior T Sakurai, A Amemiya, M Ishii, I Matsuzaki, RM Chemelli, H Tanaka, ... Cell 92 (4), 573-585, 1998 | 6490 | 1998 |
| A protein kinase involved in the regulation of inflammatory cytokine biosynthesis JC Lee, JT Laydon, PC McDonnell, TF Gallagher, S Kumar, D Green, ... Nature 372 (6508), 739-746, 1994 | 4135 | 1994 |
| Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14 RS Ames, HM Sarau, JK Chambers, RN Willette, NV Aiyar, AM Romanic, ... Nature 401 (6750), 282-286, 1999 | 1240 | 1999 |
| Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site PR Young, MM McLaughlin, S Kumar, S Kassis, ML Doyle, D McNulty, ... Journal of Biological Chemistry 272 (18), 12116-12121, 1997 | 742 | 1997 |
| Proteolytic Activity of Human Osteoclast Cathepsin K: EXPRESSION, PURIFICATION, ACTIVATION, AND SUBSTRATE IDENTIFICATION (∗) MJ Bossard, TA Tomaszek, SK Thompson, BY Amegadzie, CR Hanning, ... Journal of Biological Chemistry 271 (21), 12517-12524, 1996 | 636 | 1996 |
| Hydrophilic interaction chromatography reduces the complexity of the phosphoproteome and improves global phosphopeptide isolation and detection DE McNulty, RS Annan Molecular & cellular proteomics 7 (5), 971-980, 2008 | 444 | 2008 |
| Examination of micro-tip reversed-phase liquid chromatographic extraction of peptide pools for mass spectrometric analysis H Erdjument-Bromage, M Lui, L Lacomis, A Grewal, RS Annan, ... Journal of Chromatography A 826 (2), 167-181, 1998 | 258 | 1998 |
| DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors PA Harris, BW King, D Bandyopadhyay, SB Berger, N Campobasso, ... Journal of medicinal chemistry 59 (5), 2163-2178, 2016 | 246 | 2016 |
| Antitumor activity of an allosteric inhibitor of centromere-associated protein-E KW Wood, L Lad, L Luo, X Qian, SD Knight, N Nevins, K Brejc, D Sutton, ... Proceedings of the National Academy of Sciences 107 (13), 5839-5844, 2010 | 229 | 2010 |
| Determination of the monomer-dimer equilibrium of interleukin-8 reveals it is a monomer at physiological concentrations SD Burrows, ML Doyle, KP Murphy, SG Franklin, JR White, I Brooks, ... Biochemistry 33 (43), 12741-12745, 1994 | 212 | 1994 |
| Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction AG Gilmartin, TH Faitg, M Richter, A Groy, MA Seefeld, MG Darcy, X Peng, ... Nature chemical biology 10 (3), 181-187, 2014 | 208 | 2014 |
| Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils JR White, C Imburgia, E Dul, E Appelbaum, K O'Donnell, DJ O'Shannessy, ... Journal of leukocyte biology 62 (5), 667-675, 1997 | 207 | 1997 |
| Binding Interactions of Human Interleukin 5 with Its Receptor α Subunit: LARGE SCALE PRODUCTION, STRUCTURAL, AND FUNCTIONAL STUDIES OF DROSOPHILA-EXPRESSED RECOMBINANT PROTEINS (∗) K Johanson, E Appelbaum, M Doyle, P Hensley, B Zhao, ... Journal of Biological Chemistry 270 (16), 9459-9471, 1995 | 196 | 1995 |
| Autocatalytic activation of human cathepsin K MS McQueney, BY Amegadzie, K D'Alessio, CR Hanning, ... Journal of Biological Chemistry 272 (21), 13955-13960, 1997 | 189 | 1997 |
| Mistranslational errors associated with the rare arginine codon CGG in Escherichia coli DE McNulty, BA Claffee, MJ Huddleston, JF Kane Protein expression and purification 27 (2), 365-374, 2003 | 177 | 2003 |
| ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism L Luo, CA Parrish, N Nevins, DE McNulty, AM Chaudhari, JD Carson, ... Nature chemical biology 3 (11), 722-726, 2007 | 127 | 2007 |
| Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals … TA Berkhout, HM Sarau, K Moores, JR White, N Elshourbagy, ... Journal of Biological Chemistry 272 (26), 16404-16413, 1997 | 124 | 1997 |
| MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation DE McNulty, Z Li, CD White, DB Sacks, RS Annan Journal of biological chemistry 286 (17), 15010-15021, 2011 | 121 | 2011 |
| Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia MB Pappalardi, K Keenan, M Cockerill, WA Kellner, A Stowell, C Sherk, ... Nature cancer 2 (10), 1002-1017, 2021 | 118 | 2021 |
| IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner Z Li, DE McNulty, KJM Marler, L Lim, C Hall, RS Annan, DB Sacks Journal of Biological Chemistry 280 (14), 13871-13878, 2005 | 114 | 2005 |
