Joel Dudley
Joel Dudley
Institute Director and Associate Professor, Icahn School of Medicine at Mount Sinai
Verified email at - Homepage
TitleCited byYear
MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0
K Tamura, J Dudley, M Nei, S Kumar
Molecular biology and evolution 24 (8), 1596-1599, 2007
MEGA: molecular evolutionary genetics analysis software for microcomputers
S Kumar, K Tamura, M Nei
Bioinformatics 10 (2), 189-191, 1994
Personal omics profiling reveals dynamic molecular and medical phenotypes
R Chen, GI Mias, J Li-Pook-Than, L Jiang, HYK Lam, R Chen, E Miriami, ...
Cell 148 (6), 1293-1307, 2012
TimeTree: a public knowledge-base of divergence times among organisms
SB Hedges, J Dudley, S Kumar
Bioinformatics 22 (23), 2971-2972, 2006
Clinical assessment incorporating a personal genome
EA Ashley, AJ Butte, MT Wheeler, R Chen, TE Klein, FE Dewey, ...
The Lancet 375 (9725), 1525-1535, 2010
Discovery and preclinical validation of drug indications using compendia of public gene expression data
M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ...
Science translational medicine 3 (96), 96ra77-96ra77, 2011
Deep patient: an unsupervised representation to predict the future of patients from the electronic health records
R Miotto, L Li, BA Kidd, JT Dudley
Scientific reports 6, 26094, 2016
Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease
JT Dudley, M Sirota, M Shenoy, RK Pai, S Roedder, AP Chiang, ...
Science translational medicine 3 (96), 96ra76-96ra76, 2011
Exploiting drug–disease relationships for computational drug repositioning
JT Dudley, T Deshpande, AJ Butte
Briefings in bioinformatics 12 (4), 303-311, 2011
Gene expression elucidates functional impact of polygenic risk for schizophrenia
M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ...
Nature neuroscience 19 (11), 1442, 2016
Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets
S Suthram, JT Dudley, AP Chiang, R Chen, TJ Hastie, AJ Butte
PLoS computational biology 6 (2), e1000662, 2010
Deep learning for healthcare: review, opportunities and challenges
R Miotto, F Wang, S Wang, X Jiang, JT Dudley
Briefings in bioinformatics 19 (6), 1236-1246, 2017
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ...
Cancer discovery 3 (12), 1364-1377, 2013
Identification of type 2 diabetes subgroups through topological analysis of patient similarity
L Li, WY Cheng, BS Glicksberg, O Gottesman, R Tamler, R Chen, ...
Science translational medicine 7 (311), 311ra174-311ra174, 2015
Geospatial resolution of human and bacterial diversity with city-scale metagenomics
E Afshinnekoo, C Meydan, S Chowdhury, D Jaroudi, C Boyer, N Bernstein, ...
Cell systems 1 (1), 72-87, 2015
In silico research in the era of cloud computing
JT Dudley, AJ Butte
Nature biotechnology 28 (11), 1181, 2010
Unifying immunology with informatics and multiscale biology
BA Kidd, LA Peters, EE Schadt, JT Dudley
Nature immunology 15 (2), 118, 2014
Disease signatures are robust across tissues and experiments
JT Dudley, R Tibshirani, T Deshpande, AJ Butte
Molecular systems biology 5 (1), 2009
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence
FE Dewey, R Chen, SP Cordero, KE Ormond, C Caleshu, KJ Karczewski, ...
PLoS genetics 7 (9), e1002280, 2011
Genome-wide significant loci: how important are they?: systems genetics to understand heritability of coronary artery disease and other common complex disorders
JLM Björkegren, JC Kovacic, JT Dudley, EE Schadt
Journal of the American College of Cardiology 65 (8), 830-845, 2015
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Articles 1–20