Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4 JE Swedberg, LV Nigon, JC Reid, SJ de Veer, CM Walpole, CR Stephens, ... Chemistry & biology 16 (6), 633-643, 2009 | 141 | 2009 |
The ghrelin axis—does it have an appetite for cancer progression? LK Chopin, I Seim, CM Walpole, AC Herington Endocrine reviews 33 (6), 849-891, 2012 | 122 | 2012 |
Kallikrein-Related Peptidase 7 Promotes Multicellular Aggregation via the α5β1 Integrin Pathway and Paclitaxel Chemoresistance in Serous Epithelial Ovarian … Y Dong, OL Tan, D Loessner, C Stephens, C Walpole, GM Boyle, ... Cancer research 70 (7), 2624-2633, 2010 | 110 | 2010 |
Ghrelin and cancer L Chopin, C Walpole, I Seim, P Cunningham, R Murray, E Whiteside, ... Molecular and cellular endocrinology 340 (1), 65-69, 2011 | 105 | 2011 |
The expanding roles of the ghrelin-gene derived peptide obestatin in health and disease I Seim, C Walpole, L Amorim, P Josh, A Herington, L Chopin Molecular and cellular endocrinology 340 (1), 111-117, 2011 | 74 | 2011 |
Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment Y Dong, C Stephens, C Walpole, JE Swedberg, GM Boyle, PG Parsons, ... PloS one 8 (2), e57056, 2013 | 69 | 2013 |
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk JN Painter, TA O'mara, J Batra, T Cheng, FA Lose, J Dennis, ... Human molecular genetics 24 (5), 1478-1492, 2015 | 65 | 2015 |
Selective anti-proliferative activities of Carica papaya leaf juice extracts against prostate cancer S Pandey, C Walpole, PJ Cabot, PN Shaw, J Batra, AK Hewavitharana Biomedicine & pharmacotherapy 89, 515-523, 2017 | 58 | 2017 |
Ghrelin gene‐related peptides: Multifunctional endocrine/autocrine modulators in health and disease I Seim, L Amorim, C Walpole, S Carter, LK Chopin, AC Herington Clinical and Experimental Pharmacology and Physiology 37 (1), 125-131, 2010 | 55 | 2010 |
Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitroby ghrelin I Seim, PL Jeffery, L De Amorim, CM Walpole, J Fung, EJ Whiteside, ... Reproductive Biology and Endocrinology 11, 1-9, 2013 | 52 | 2013 |
Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model YS Lee, LJ O'Brien, CM Walpole, FE Pearson, IM Leal-Rojas, ... Journal for immunotherapy of cancer 9 (3), 2021 | 34 | 2021 |
Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate naïve and memory NY-ESO-1-specific CD8+ T cells KA Masterman, OL Haigh, KM Tullett, IM Leal-Rojas, C Walpole, ... Journal for immunotherapy of cancer 8 (2), 2020 | 31 | 2020 |
Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide I Seim, PL Jeffery, PB Thomas, CM Walpole, M Maugham, JNT Fung, ... Endocrine 52, 609-617, 2016 | 29 | 2016 |
Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection MAA Sikder, RB Rashid, T Ahmed, I Sebina, DR Howard, MA Ullah, ... Immunity 56 (5), 1098-1114. e10, 2023 | 28 | 2023 |
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells FE Pearson, KM Tullett, IM Leal‐Rojas, OL Haigh, KA Masterman, ... Clinical & translational immunology 9 (6), e1141, 2020 | 28 | 2020 |
Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines EJ Whiteside, I Seim, JP Pauli, AJ O'Keeffe, PB Thomas, SL Carter, ... International journal of oncology 43 (2), 566-574, 2013 | 28 | 2013 |
Bio-guided fractionation of papaya leaf juice for delineating the components responsible for the selective anti-proliferative effects on prostate cancer cells S Pandey, C Walpole, PN Shaw, PJ Cabot, AK Hewavitharana, J Batra Frontiers in pharmacology 9, 1319, 2018 | 22 | 2018 |
Fusion transcript loci share many genomic features with non-fusion loci J Lai, J An, I Seim, C Walpole, A Hoffman, L Moya, S Srinivasan, ... BMC genomics 16, 1-12, 2015 | 19 | 2015 |
A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness J Lai, L Moya, J An, A Hoffman, S Srinivasan, J Panchadsaram, ... Scientific reports 7 (1), 16862, 2017 | 18 | 2017 |
The long non-coding RNA GHSROS facilitates breast cancer cell migration and orthotopic xenograft tumour growth PB Thomas, I Seim, PL Jeffery, MD Gahete, M Maugham, GJ Crisp, ... International Journal of Oncology 55 (6), 1223-1236, 2019 | 16 | 2019 |