Marcin Drag
Marcin Drag
Professor, Department of Chemical Biology and Bioimaging, Wroclaw University of Technology
Verified email at - Homepage
Cited by
Cited by
Emerging principles in protease-based drug discovery
M Drag, GS Salvesen
Nature reviews Drug discovery 9 (9), 690-701, 2010
FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
C Pop, A Oberst, M Drag, BJ Van Raam, SJ Riedl, DR Green, ...
Biochemical Journal 433 (3), 447-457, 2011
A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis
J Walters, C Pop, FL Scott, M Drag, P Swartz, C Mattos, GS Salvesen, ...
Biochemical Journal 424 (3), 335-345, 2009
Caspase substrates and inhibitors
M Poręba, A Stróżyk, GS Salvesen, M Drąg
Cold Spring Harbor perspectives in biology 5 (8), a008680, 2013
Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs
J Mikolajczyk, M Drag, M Békés, JT Cao, Z Ronai, GS Salvesen
Journal of Biological Chemistry 282 (36), 26217-26224, 2007
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials
TS Skinner-Adams, CM Stack, KR Trenholme, CL Brown, J Grembecka, ...
Trends in biochemical sciences 35 (1), 53-61, 2010
DeSUMOylating enzymes—SENPs
M Drag, GS Salvesen
IUBMB life 60 (11), 734-742, 2008
Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling
P Kasperkiewicz, M Poreba, SJ Snipas, H Parker, CC Winterbourn, ...
Proceedings of the National Academy of Sciences 111 (7), 2518-2523, 2014
Metallo-aminopeptidase inhibitors
A Mucha, M Drag, JP Dalton, P Kafarski
Biochimie 92 (11), 1509-1529, 2010
Distribution and paralogue specificity of mammalian deSUMOylating enzymes
N Kolli, J Mikolajczyk, M Drag, D Mukhopadhyay, N Moffatt, M Dasso, ...
Biochemical Journal 430 (2), 335-344, 2010
Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug …
M Drag, P Surowiak, M Drag-Zalesinska, M Dietel, H Lage, J Oleksyszyn
Molecules 14 (4), 1639-1651, 2009
Esters of betulin and betulinic acid with amino acids have improved water solubility and are selectively cytotoxic toward cancer cells
M Drag-Zalesinska, J Kulbacka, J Saczko, T Wysocka, M Zabel, ...
Bioorganic & medicinal chemistry letters 19 (16), 4814-4817, 2009
Aminopeptidase fingerprints, an integrated approach for identification of good substrates and optimal inhibitors
M Drag, M Bogyo, JA Ellman, GS Salvesen
Journal of Biological Chemistry 285 (5), 3310-3318, 2010
Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides
E Zervoudi, A Papakyriakou, D Georgiadou, I Evnouchidou, A Gajda, ...
Biochemical Journal 435 (2), 411-420, 2011
Mechanism and specificity of the human paracaspase MALT1
J Hachmann, SJ Snipas, BJ van Raam, EM Cancino, EJ Houlihan, ...
Biochemical Journal 443 (1), 287-295, 2012
Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design
W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ...
BioRxiv, 2020
SUMO-mediated regulation of NLRP3 modulates inflammasome activity
R Barry, SW John, G Liccardi, T Tenev, I Jaco, CH Chen, J Choi, ...
Nature communications 9 (1), 1-14, 2018
Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum
M Poreba, S McGowan, TS Skinner-Adams, KR Trenholme, DL Gardiner, ...
PLoS One 7 (2), e31938, 2012
Activation and specificity of human caspase-10
K Wachmann, C Pop, BJ van Raam, M Drag, PD Mace, SJ Snipas, ...
Biochemistry 49 (38), 8307-8315, 2010
α-Aminoalkylphosphonates as a tool in experimental optimisation of P1 side chain shape of potential inhibitors in S1 pocket of leucine-and neutral aminopeptidases
M Drąg, J Grembecka, M Pawełczak, P Kafarski
European journal of medicinal chemistry 40 (8), 764-771, 2005
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