William Charman
William Charman
Dean, Faculty of Pharmacy & Pharmaceutical Sciences, Monash University
Verified email at monash.edu - Homepage
Title
Cited by
Cited by
Year
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
CJH Porter, NL Trevaskis, WN Charman
Nature reviews Drug discovery 6 (3), 231-248, 2007
15052007
Strategies to address low drug solubility in discovery and development
HD Williams, NL Trevaskis, SA Charman, RM Shanker, WN Charman, ...
Pharmacological reviews 65 (1), 315-499, 2013
10342013
Identification of an antimalarial synthetic trioxolane drug development candidate
JL Vennerstrom, S Arbe-Barnes, R Brun, SA Charman, FCK Chiu, ...
Nature 430 (7002), 900-904, 2004
6872004
Lipid-based vehicles for the oral delivery of poorly water soluble drugs
AJ Humberstone, WN Charman
Advanced drug delivery reviews 25 (1), 103-128, 1997
6831997
Enhancing intestinal drug solubilisation using lipid-based delivery systems
CJH Porter, CW Pouton, JF Cuine, WN Charman
Advanced drug delivery reviews 60 (6), 673-691, 2008
6682008
Physicochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH
WN Charman, CJH Porter, S Mithani, JB Dressman
Journal of pharmaceutical sciences 86 (3), 269-282, 1997
6651997
Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound
SA Charman, WN Charman, MC Rogge, TD Wilson, FJ Dutko, CW Pouton
Pharmaceutical research 9 (1), 87-93, 1992
5501992
Prodrugs
VJ Stella, WNA Charman, VH Naringrekar
Drugs 29 (5), 455-473, 1985
547*1985
Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine
SM Khoo, AJ Humberstone, CJH Porter, GA Edwards, WN Charman
International journal of pharmaceutics 167 (1-2), 155-164, 1998
4781998
In vitro assessment of oral lipid based formulations
CJH Porter, WN Charman
Advanced drug delivery reviews 50, S127-S147, 2001
4262001
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
SA Charman, S Arbe-Barnes, IC Bathurst, R Brun, M Campbell, ...
Proceedings of the National Academy of Sciences 108 (11), 4400-4405, 2011
3522011
Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update
NL Trevaskis, WN Charman, CJH Porter
Advanced drug delivery reviews 60 (6), 702-716, 2008
3402008
Intestinal lymphatic drug transport: an update
CJH Porter, WN Charman
Advanced drug delivery reviews 50 (1-2), 61-80, 2001
3352001
Evaluation of the in‐vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products
L Sek, CJH Porter, AM Kaukonen, WN Charman
Journal of pharmacy and pharmacology 54 (1), 29-41, 2002
2802002
Lipids, lipophilic drugs, and oral drug delivery—some emerging concepts
WN Charman
Journal of pharmaceutical sciences 89 (8), 967-978, 2000
2742000
Effect of short‐, medium‐, and long‐chain fatty acid‐based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of …
SM Caliph, WN Charman, CJH Porter
Journal of pharmaceutical sciences 89 (8), 1073-1084, 2000
2612000
Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation
CJH Porter, AM Kaukonen, BJ Boyd, GA Edwards, WN Charman
Pharmaceutical research 21 (8), 1405-1412, 2004
2482004
The mucosa of the small intestine
MM Doherty, WN Charman
Clinical pharmacokinetics 41 (4), 235-253, 2002
2472002
Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors …
JM Coteron, M Marco, J Esquivias, X Deng, KL White, J White, M Koltun, ...
Journal of medicinal chemistry 54 (15), 5540-5561, 2011
2392011
Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: studies with halofantrine
CJH Porter, AM Kaukonen, A Taillardat-Bertschinger, BJ Boyd, ...
Journal of pharmaceutical sciences 93 (5), 1110-1121, 2004
2002004
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