Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases SM Sondhi, N Singh, A Kumar, O Lozach, L Meijer Bioorganic & medicinal chemistry 14 (11), 3758-3765, 2006 | 472 | 2006 |
Roscovitine Targets, Protein Kinases and Pyridoxal Kinase*[Boxs] S Bach, M Knockaert, J Reinhardt, O Lozach, S Schmitt, B Baratte, ... Journal of Biological Chemistry 280 (35), 31208-31219, 2005 | 428 | 2005 |
Synthesis and target identification of hymenialdisine analogs Y Wan, W Hur, CY Cho, Y Liu, FJ Adrian, O Lozach, S Bach, T Mayer, ... Chemistry & biology 11 (2), 247-259, 2004 | 177 | 2004 |
Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex A Echalier, K Bettayeb, Y Ferandin, O Lozach, M Clément, A Valette, ... Journal of medicinal chemistry 51 (4), 737-751, 2008 | 174 | 2008 |
Meriolins, a new class of cell death–inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases K Bettayeb, OM Tirado, S Marionneau-Lambot, Y Ferandin, O Lozach, ... Cancer Research 67 (17), 8325-8334, 2007 | 171 | 2007 |
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B … M Debdab, F Carreaux, S Renault, M Soundararajan, O Fedorov, ... Journal of medicinal chemistry 54 (12), 4172-4186, 2011 | 165 | 2011 |
Anticancer alkaloid lamellarins inhibit protein kinases D Baunbæk, N Trinkler, Y Ferandin, O Lozach, P Ploypradith, S Rucirawat, ... Marine Drugs 6 (4), 514-527, 2008 | 157 | 2008 |
Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents AH Abadi, SM Abou-Seri, DE Abdel-Rahman, C Klein, O Lozach, L Meijer European journal of medicinal chemistry 41 (3), 296-305, 2006 | 143 | 2006 |
Synthesis of novel 5-substituted indirubins as protein kinases inhibitors A Beauchard, Y Ferandin, S Frère, O Lozach, M Blairvacq, L Meijer, ... Bioorganic & medicinal chemistry 14 (18), 6434-6443, 2006 | 137 | 2006 |
Soluble 3′, 6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase-3 alter circadian period K Vougogiannopoulou, Y Ferandin, K Bettayeb, V Myrianthopoulos, ... Journal of medicinal chemistry 51 (20), 6421-6431, 2008 | 135 | 2008 |
Structure-based design and synthesis of 2-benzylidene-benzofuran-3-ones as flavopiridol mimics J Schoepfer, H Fretz, B Chaudhuri, L Muller, E Seeber, L Meijer, O Lozach, ... Journal of medicinal chemistry 45 (9), 1741-1747, 2002 | 134 | 2002 |
Synthesis of acridinyl-thiazolino derivatives and their evaluation for anti-inflammatory, analgesic and kinase inhibition activities SM Sondhi, N Singh, AM Lahoti, K Bajaj, A Kumar, O Lozach, L Meijer Bioorganic & medicinal chemistry 13 (13), 4291-4299, 2005 | 122 | 2005 |
Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives F Giraud, G Alves, E Debiton, L Nauton, V Théry, E Durieu, Y Ferandin, ... Journal of medicinal chemistry 54 (13), 4474-4489, 2011 | 121 | 2011 |
10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A H Falke, A Chaikuad, A Becker, N Loaëc, O Lozach, S Abu Jhaisha, ... Journal of medicinal chemistry 58 (7), 3131-3143, 2015 | 116 | 2015 |
Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents S Routier, JY Mérour, N Dias, A Lansiaux, C Bailly, O Lozach, L Meijer Journal of medicinal chemistry 49 (2), 789-799, 2006 | 116 | 2006 |
Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp. D Laurent, V Jullian, A Parenty, M Knibiehler, D Dorin, S Schmitt, ... Bioorganic & medicinal chemistry 14 (13), 4477-4482, 2006 | 115 | 2006 |
Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-β-carbolines M Laronze, M Boisbrun, S Léonce, B Pfeiffer, P Renard, O Lozach, ... Bioorganic & medicinal chemistry 13 (6), 2263-2283, 2005 | 111 | 2005 |
3 ‘-Substituted 7-halogenoindirubins, a new class of cell death inducing agents Y Ferandin, K Bettayeb, M Kritsanida, O Lozach, P Polychronopoulos, ... Journal of medicinal chemistry 49 (15), 4638-4649, 2006 | 110 | 2006 |
9-Cyano-1-azapaullone (cazpaullone), a glycogen synthase kinase-3 (GSK-3) inhibitor activating pancreatic β cell protection and replication H Stukenbrock, R Mussmann, M Geese, Y Ferandin, O Lozach, T Lemcke, ... Journal of medicinal chemistry 51 (7), 2196-2207, 2008 | 109 | 2008 |
Synthesis and biological evaluation of 3,6-diamino-1H-pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors M Chioua, A Samadi, E Soriano, O Lozach, L Meijer, J Marco-Contelles Bioorganic & medicinal chemistry letters 19 (16), 4566-4569, 2009 | 107 | 2009 |