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Mark von Itzstein
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Rational design of potent sialidase-based inhibitors of influenza virus replication
M Von Itzstein, WY Wu, GB Kok, MS Pegg, JC Dyason, B Jin, T Van Phan, ...
Nature 363 (6428), 418-423, 1993
24101993
The war against influenza: discovery and development of sialidase inhibitors
M Von Itzstein
Nature reviews Drug discovery 6 (12), 967-974, 2007
8422007
NAD+ cleavage activity by animal and plant TIR domains in cell death pathways
S Horsefield, H Burdett, X Zhang, MK Manik, Y Shi, J Chen, T Qi, J Gilley, ...
Science 365 (6455), 793-799, 2019
3962019
Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis
NR Taylor, M von Itzstein
Journal of medicinal chemistry 37 (5), 616-624, 1994
2811994
Evidence for a sialosyl cation transition‐state complex in the reaction of sialidase from influenza virus
AKJ Chong, MS Pegg, NR Taylor, M von ITZSTEIN
European journal of biochemistry 207 (1), 335-343, 1992
2571992
Recent advances in the synthesis of sialic acid derivatives and sialylmimetics as biological probes
MJ Kiefel, M von Itzstein
Chemical reviews 102 (2), 471-490, 2002
2422002
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases
K Hata, K Koseki, K Yamaguchi, S Moriya, Y Suzuki, S Yingsakmongkon, ...
Antimicrobial agents and chemotherapy 52 (10), 3484-3491, 2008
2272008
Second sialic acid binding site in Newcastle disease virus hemagglutinin-neuraminidase: implications for fusion
V Zaitsev, M von Itzstein, D Groves, M Kiefel, T Takimoto, A Portner, ...
Journal of virology 78 (7), 3733-3741, 2004
2122004
Glycointeractions in bacterial pathogenesis
J Poole, CJ Day, M von Itzstein, JC Paton, MP Jennings
Nature Reviews Microbiology 16 (7), 440-452, 2018
2042018
Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice
YL Huang, C Chassard, M Hausmann, M Von Itzstein, T Hennet
Nature communications 6 (1), 8141, 2015
2002015
Sialic acid dependence in rotavirus host cell invasion
T Haselhorst, FE Fleming, JC Dyason, RD Hartnell, X Yu, G Holloway, ...
Nature chemical biology 5 (2), 91-93, 2009
1972009
The synthesis of 2, 3-didehydro-2, 4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor
M von Itzstein, WY Wu, B Jin
Carbohydrate research 259 (2), 301-305, 1994
1911994
Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly
A Hinek, AV Pshezhetsky, M Von Itzstein, B Starcher
Journal of Biological Chemistry 281 (6), 3698-3710, 2006
1902006
Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid
SA Forsyth, DR MacFarlane, RJ Thomson, M Von Itzstein
Chemical Communications, 714-715, 2002
1892002
A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs
M von Itzstein, JC Dyason, SW Oliver, HF White, WY Wu, GB Kok, ...
Journal of medicinal chemistry 39 (2), 388-391, 1996
1851996
Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position
CT Holzer, M Von Itzstein, B Jin, MS Pegg, WP Stewart, WY Wu
Glycoconjugate journal 10, 40-44, 1993
1831993
Sialic acid recognition by Vibrio cholerae neuraminidase
I Moustafa, H Connaris, M Taylor, V Zaitsev, JC Wilson, MJ Kiefel, ...
Journal of Biological Chemistry 279 (39), 40819-40826, 2004
1812004
Analysis of inhibitor binding in influenza virus neuraminidase
BJ Smith, PM Colman, M Von Itzstein, B Danylec, JN Varghese
Protein Science 10 (4), 689-696, 2001
1452001
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase
S Rudrawar, JC Dyason, MA Rameix-Welti, FJ Rose, PS Kerry, ...
Nature communications 1 (1), 113, 2010
1232010
Differential Carbohydrate Recognition by Campylobacter jejuni Strain 11168: Influences of Temperature and Growth Conditions
CJ Day, J Tiralongo, RD Hartnell, CA Logue, JC Wilson, M von Itzstein, ...
PloS one 4 (3), e4927, 2009
1232009
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