Stan J.J. Brouns

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Citations	14664	9779
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Co-authors

John van der OostMicrobiology, Wageningen UniversityVerified email at wur.nl
Edze WestraProfessor of Microbiology, University of Exeter, Biosciences, ESIVerified email at exeter.ac.uk
Matthijs JorePostdoctoral Researcher, RadboudumcVerified email at radboudumc.nl
Snijders apThe Francis Crick InstituteVerified email at crick.ac.uk
Eugene KooninSenior Investigator, NCBI, NIHVerified email at ncbi.nlm.nih.gov
Kira MakarovaNCBI, NIHVerified email at ncbi.nlm.nih.gov
Mark J DickmanProfessor of Bioanalytical Science and Engineering, Dept of Chemical and Biological EngineeringVerified email at sheffield.ac.uk
Willem M de VosProfessor @ Microbiology Wageningen Netherlands @Helsinki FinlandVerified email at wur.nl
Tim KünneWageningen University and ResearchVerified email at wur.nl
Raymond StaalsAssistant Professor, Wageningen UniversityVerified email at wur.nl
Konstantin SeverinovVerified email at waksman.rutgers.edu
Blake WiedenheftAssistant Professor Microbiology and Immunology, Montana State UniversityVerified email at montana.edu
Daan C. SwartsAssistant Professor/Personal Investigator | Wageningen University & ResearchVerified email at wur.nl
Franklin L. NobregaLecturer in Microbiology, University of SouthamptonVerified email at soton.ac.uk
Ekaterina SemenovaAssistant Research Professor, Waksman Institute, Rutgers University NJVerified email at waksman.rutgers.edu
Sylvain MoineauUniversité LavalVerified email at bcm.ulaval.ca
Daniel HaftStaff Scientist, National Center for Biotechnology Information, NIHVerified email at nih.gov
Rodolphe BarrangouNorth Carolina State UniversityVerified email at ncsu.edu
Philippe HORVATHSenior scientist, DuPont Nutrition and HealthVerified email at dupont.com
Alexander YakuninUniversity of Toronto (Canada), Bangor University (UK)Verified email at bangor.ac.uk

Stan J.J. Brouns

Associate Professor Molecular Microbiology, Delft University of Technology

Verified email at tudelft.nl - Homepage

CRISPR Bacteriophage Antibiotic resistance


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Small CRISPR RNAs guide antiviral defense in prokaryotes SJJ Brouns, MM Jore, M Lundgren, ER Westra, RJH Slijkhuis, ... Science 321 (5891), 960-964, 2008	2319	2008
Evolution and classification of the CRISPR–Cas systems KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ... Nature Reviews Microbiology 9 (6), 467-477, 2011	2232	2011
An updated evolutionary classification of CRISPR–Cas systems KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ... Nature Reviews Microbiology 13 (11), 722-736, 2015	1615	2015
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ... Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011	757	2011
CRISPR-based adaptive and heritable immunity in prokaryotes J Van der Oost, MM Jore, ER Westra, M Lundgren, SJJ Brouns Trends in biochemical sciences 34 (8), 401-407, 2009	557	2009
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529, 2011	544	2011
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012	543	2012
Structures of the RNA-guided surveillance complex from a bacterial immune system B Wiedenheft, GC Lander, K Zhou, MM Jore, SJJ Brouns, J van der Oost, ... Nature 477 (7365), 486-489, 2011	465	2011
CRISPR interference directs strand specific spacer acquisition DC Swarts, C Mosterd, MWJ Van Passel, SJJ Brouns PloS one 7 (4), e35888, 2012	355	2012
The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost Annual review of genetics 46, 311-339, 2012	325	2012
DNA-guided DNA interference by a prokaryotic Argonaute DC Swarts, MM Jore, ER Westra, Y Zhu, JH Janssen, AP Snijders, ... Nature 507 (7491), 258-261, 2014	270	2014
Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry RHH van den Heuvel, E van Duijn, H Mazon, SA Synowsky, K Lorenzen, ... Analytical chemistry 78 (21), 7473-7483, 2006	259	2006
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020	236	2020
H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO ER Westra, Ü Pul, N Heidrich, MM Jore, M Lundgren, T Stratmann, ... Molecular microbiology 77 (6), 1380-1393, 2010	232	2010
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014	228	2014
Degenerate target sites mediate rapid primed CRISPR adaptation PC Fineran, MJH Gerritzen, M Suárez-Diez, T Künne, J Boekhorst, ... Proceedings of the National Academy of Sciences 111 (16), E1629-E1638, 2014	221	2014
CRISPR-Cas: Adapting to change SA Jackson, RE McKenzie, RD Fagerlund, SN Kieper, PC Fineran, ... Science 356 (6333), 2017	212	2017
CRISPRTarget: bioinformatic prediction and analysis of crRNA targets A Biswas, JN Gagnon, SJJ Brouns, PC Fineran, CM Brown RNA biology 10 (5), 817-827, 2013	197	2013
Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ... PLoS Genet 9 (9), e1003742, 2013	195	2013
Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG FP Douillard, A Ribbera, R Kant, TE Pietilä, HM Järvinen, M Messing, ... PLoS Genet 9 (8), e1003683, 2013	181	2013

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