Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target D Liu, CC Wong, L Fu, H Chen, L Zhao, C Li, Y Zhou, Y Zhang, W Xu, ... Science translational medicine 10 (437), eaap9840, 2018 | 212 | 2018 |
RNA N6-methyladenosine methyltransferase METTL3 facilitates colorectal cancer by activating the m6A-GLUT1-mTORC1 axis and is a therapeutic target H Chen, S Gao, W Liu, CC Wong, J Wu, J Wu, D Liu, H Gou, W Kang, ... Gastroenterology 160 (4), 1284-1300. e16, 2021 | 191 | 2021 |
A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses H Zhao, J Zhou, K Zhang, H Chu, D Liu, VKM Poon, CCS Chan, ... Scientific reports 6 (1), 22008, 2016 | 169 | 2016 |
O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress W Xu, X Zhang, J Wu, L Fu, K Liu, D Liu, GG Chen, P Bo-san Lai, N Wong, ... Journal of hepatology 67 (2), 310-320, 2017 | 119 | 2017 |
CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma L Jiang, YD Yang, L Fu, W Xu, D Liu, Q Liang, X Zhang, L Xu, XY Guan, ... Oncotarget 5 (17), 7663, 2014 | 98 | 2014 |
In colorectal cancer cells with mutant KRAS, SLC25A22-mediated glutaminolysis reduces DNA demethylation to increase WNT signaling, stemness, and drug resistance CC Wong, J Xu, X Bian, JL Wu, W Kang, Y Qian, W Li, H Chen, H Gou, ... Gastroenterology 159 (6), 2163-2180. e6, 2020 | 97 | 2020 |
Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer X Xia, WKK Wu, SH Wong, D Liu, TNY Kwong, G Nakatsu, PS Yan, ... Microbiome 8, 1-13, 2020 | 86 | 2020 |
SARS-CoV-2 activates lung epithelial cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients H Chen, W Liu, Y Wang, D Liu, L Zhao, J Yu EBioMedicine 70, 2021 | 65 | 2021 |
Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis YJ Li C, Wang Y, Liu D, Wong CC, Coker OO, Zhang X, Liu C, Zhou Y, Liu Y ... Gut, 2022 | 63 | 2022 |
APLN promotes hepatocellular carcinoma through activating PI3K/Akt pathway and is a druggable target H Chen, CC Wong, D Liu, MYY Go, B Wu, S Peng, M Kuang, N Wong, ... Theranostics 9 (18), 5246, 2019 | 55 | 2019 |
DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients J Tang, H Chen, CC Wong, D Liu, T Li, X Wang, J Ji, JJY Sung, JY Fang, ... Oncogene 37 (22), 3006-3021, 2018 | 52 | 2018 |
Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma J Shen, H Tsoi, Q Liang, ESH Chu, D Liu, A Yu, TF Chan, X Li, JJY Sung, ... Oncogene 35 (49), 6271-6280, 2016 | 40 | 2016 |
Rapid assembly of multiple-exon cDNA directly from genomic DNA X An, J Lu, J Huang, B Zhang, D Liu, X Zhang, J Chen, Y Zhou, Y Tong PLoS One 2 (11), e1179, 2007 | 34 | 2007 |
Activated Natural Killer Cell Promotes Nonalcoholic Steatohepatitis Through Mediating JAK/STAT Pathway JY Feixue Wang, Xiang Zhang, Weixin Liu, Yunfei Zhou, Wenchao Wei, Dabin Liu ... Cell Mol Gastroenterol Hepatol, 2022 | 31 | 2022 |
Squalene epoxidase induces nonalcoholic steatohepatitis via binding to carbonic anhydrase III and is a therapeutic target D Liu, CC Wong, Y Zhou, C Li, H Chen, F Ji, MYY Go, F Wang, H Su, ... Gastroenterology 160 (7), 2467-2482. e3, 2021 | 31 | 2021 |
Classifying gastric cancer using FLORA reveals clinically relevant molecular subtypes and highlights LINC01614 as a biomarker for patient prognosis Y Chen, WY Cheng, H Shi, S Huang, H Chen, D Liu, W Xu, J Yu, J Wang Oncogene 40 (16), 2898-2909, 2021 | 30 | 2021 |
The cholesterol uptake regulator PCSK9 promotes and is a therapeutic target in APC/KRAS-mutant colorectal cancer JY Chi Wong, Jianlin Wu, Fenfen Ji, Wei Kang, Xiqing Bian, Huarong Chen, Lam ... Nature communications, 2022 | 25 | 2022 |
Production and Characterization of a humanized single-chain antibody against human integrin αvβ3 protein D Liu, C Wang, C Li, X Zhang, B Zhang, Z Mi, X An, Y Tong Journal of Biological Chemistry 286 (27), 24500-24507, 2011 | 15 | 2011 |
Prokaryotic expression and purification of HA1 and HA2 polypeptides for serological analysis of the 2009 pandemic H1N1 influenza virus D Liu, B Si, C Li, Z Mi, X An, C Qin, W Liu, Y Tong Journal of virological methods 172 (1-2), 16-21, 2011 | 15 | 2011 |
High level soluble expression, one-step purification and characterization of HIV-1 p24 protein B Zhang, D Liu, Z Bao, B Chen, C Li, H Jiang, X Wang, Z Mi, X An, J Lu, ... Virology Journal 8, 1-6, 2011 | 14 | 2011 |