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Michal Komorowski
Michal Komorowski
Institute of Fundamental Technological Research, Polish Academy of Sciences
Verified email at sysbiosig.org - Homepage
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Cited by
Cited by
Year
Sensitivity, robustness, and identifiability in stochastic chemical kinetics models
M Komorowski, MJ Costa, DA Rand, MPH Stumpf
Proceedings of the National Academy of Sciences 108 (21), 8645, 2011
2352011
Maximizing the information content of experiments in systems biology
J Liepe, S Filippi, M Komorowski, MPH Stumpf
PLoS computational biology 9 (1), e1002888, 2013
2192013
Bayesian inference of biochemical kinetic parameters using the linear noise approximation
M Komorowski, B Finkenstädt, C Harper, D Rand
BMC bioinformatics 10 (1), 343, 2009
1552009
Reconstruction of transcriptional dynamics from gene reporter data using differential equations
B Finkenstädt, EA Heron, M Komorowski, K Edwards, S Tang, CV Harper, ...
Bioinformatics 24 (24), 2901-2907, 2008
882008
Nitrogen and Carbon Status Are Integrated at the Transcriptional Level by the Nitrogen Regulator NtrC In Vivo
J Schumacher, V Behrends, Z Pan, DR Brown, F Heydenreich, MR Lewis, ...
MBio 4 (6), 10.1128/mbio. 00881-13, 2013
652013
Quantifying intrinsic and extrinsic noise in gene transcription using the linear noise approximation: An application to single cell data
B Finkenstädt, DJ Woodcock, M Komorowski, CV Harper, JRE Davis, ...
The Annals of Applied Statistics, 1960-1982, 2013
542013
Decomposing Noise in Biochemical Signaling Systems Highlights the Role of Protein Degradation
M Komorowski, J Miekisz, MPH Stumpf
Biophysical Journal 104 (8), 1783-93, 2013
502013
Translational repression contributes greater noise to gene expression than transcriptional repression
M Komorowski, J Miekisz, AM Kierzek
Biophysical Journal 96 (2), 372-384, 2009
432009
Information-theoretic analysis of multivariate single-cell signaling responses
T Jetka, K Nienałtowski, T Winarski, S Błoński, M Komorowski
PLoS computational biology 15 (7), e1007132, 2019
392019
Nuclear translocation of STAT3 and NF-κB are independent of each other but NF-κB supports expression and activation of STAT3
A Martincuks, K Andryka, A Küster, H Schmitz-Van de Leur, ...
Cellular signalling 32, 36-47, 2017
382017
Quantitative biology: theory, computational methods, and models
B Munsky, WS Hlavacek, LS Tsimring
MIT Press, 2018
372018
Using a single fluorescent reporter gene to infer half-life of extrinsic noise and other parameters of gene expression
M Komorowski, B Finkenstädt, D Rand
Biophysical journal 98 (12), 2759-2769, 2010
372010
Robustness and information transfer within IL-6-induced JAK/STAT signalling
U Billing, T Jetka, L Nortmann, N Wundrack, M Komorowski, S Waldherr, ...
Communications biology 2 (1), 27, 2019
352019
An information-theoretic framework for deciphering pleiotropic and noisy biochemical signaling
T Jetka, K Nienałtowski, S Filippi, MPH Stumpf, M Komorowski
Nature communications 9 (1), 4591, 2018
332018
The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling
J Fiebelkow, A Guendel, B Guendel, N Mehwald, T Jetka, M Komorowski, ...
Cell Communication and Signaling 19, 1-19, 2021
282021
The limited information capacity of cross-reactive sensors drives the evolutionary expansion of signaling
M Komorowski, DS Tawfik
Cell systems 8 (1), 76-85. e6, 2019
272019
StochSens—matlab package for sensitivity analysis of stochastic chemical systems
M Komorowski, J Žurauskienė, MPH Stumpf
Bioinformatics 28 (5), 731-733, 2012
232012
Mathematical modeling reveals the functional implications of the different nuclear shuttling rates of Erk1 and Erk2
HA Harrington, M Komorowski, M Beguerisse-Díaz, GM Ratto, ...
Physical biology 9 (3), 036001, 2012
212012
Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses
P Topolewski, KE Zakrzewska, J Walczak, K Nienałtowski, ...
Science Signaling 15 (721), eabd9303, 2022
192022
Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamics
M Włodarczyk, T Lipniacki, M Komorowski
BMC Systems Biology 9 (65), 2015
19*2015
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Articles 1–20