Andrew J Deans
Andrew J Deans
Verified email at - Homepage
Cited by
Cited by
DNA interstrand crosslink repair and cancer
AJ Deans, SC West
Nature reviews cancer 11 (7), 467-480, 2011
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2
C MacKay, AC Déclais, C Lundin, A Agostinho, AJ Deans, TJ MacArtney, ...
Cell 142 (1), 65-76, 2010
The Fanconi anemia pathway maintains genome stability by coordinating replication and transcription
RA Schwab, J Nieminuszczy, F Shah, J Langton, DL Martinez, CC Liang, ...
Molecular cell 60 (3), 351-361, 2015
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
AJ Deans, SC West
Molecular cell 36 (6), 943-953, 2009
Increased platelet activation in patients with stable and acute exacerbation of COPD
JD Maclay, DA McAllister, S Johnston, J Raftis, C McGuinnes, A Deans, ...
Thorax 66 (9), 769-774, 2011
The Fanconi Anemia DNA Repair Pathway: Structural and Functional Insights into a Complex Disorder
H Walden, AJ Deans
Annual Review of Biophysics 43 (1), 2014
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex
SJ Collis, A Ciccia, AJ Deans, Z Hořejší, JS Martin, SL Maslen, JM Skehel, ...
Molecular cell 32 (3), 313-324, 2008
BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage
M Fabbro, K Savage, K Hobson, AJ Deans, SN Powell, GA McArthur, ...
Journal of Biological Chemistry 279 (30), 31251-31258, 2004
The architecture and evolution of cancer neochromosomes
DW Garsed, OJ Marshall, VDA Corbin, A Hsu, L Di Stefano, J Schröder, ...
Cancer cell 26 (5), 653-667, 2014
FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops
B Silva, R Pentz, AM Figueira, R Arora, YW Lee, C Hodson, ...
Nature communications 10 (1), 2253, 2019
The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
R Lu, JJ O’Rourke, AP Sobinoff, JAM Allen, CB Nelson, CG Tomlinson, ...
Nature communications 10 (1), 2252, 2019
Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers
AJ Deans, KK Khanna, CJ McNees, C Mercurio, J Heierhorst, ...
Cancer research 66 (16), 8219-8226, 2006
Mechanism of ubiquitination and deubiquitination in the Fanconi anemia pathway
S van Twest, VJ Murphy, C Hodson, W Tan, P Swuec, JJ O’Rourke, ...
Molecular cell 65 (2), 247-259, 2017
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer
E Sanij, KM Hannan, J Xuan, S Yan, JE Ahern, AS Trigos, N Brajanovski, ...
Nature communications 11 (1), 2641, 2020
The DNA translocase activity of FANCM protects stalled replication forks
AN Blackford, RA Schwab, J Nieminuszczy, AJ Deans, SC West, ...
Human molecular genetics 21 (9), 2005-2016, 2012
Neuromuscular electrical stimulation prevents muscle function deterioration in exacerbated COPD: a pilot study
S Giavedoni, A Deans, P McCaughey, E Drost, W MacNee, ...
Respiratory medicine 106 (10), 1429-1434, 2012
MAD1 and p27KIP1 Cooperate To Promote Terminal Differentiation of Granulocytes and To Inhibit Myc Expression and Cyclin E-CDK2 Activity
GA McArthur, KP Foley, ML Fero, CR Walkley, AJ Deans, JM Roberts, ...
Molecular and cellular biology 22 (9), 3014-3023, 2002
The FA core complex contains a homo-dimeric catalytic module for the symmetric mono-ubiquitination of FANCI-FANCD2
P Swuec, L Renault, A Borg, F Shah, VJ Murphy, S van Twest, ...
Cell reports 18 (3), 611-623, 2017
Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1
CE Caldon, CM Sergio, A Burgess, AJ Deans, RL Sutherland, ...
Cell cycle 12 (4), 606-617, 2013
Monoubiquitination by the human Fanconi anemia core complex clamps FANCI: FANCD2 on DNA in filamentous arrays
W Tan, S van Twest, A Leis, R Bythell-Douglas, VJ Murphy, M Sharp, ...
elife 9, e54128, 2020
The system can't perform the operation now. Try again later.
Articles 1–20