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Simon de Veer
Simon de Veer
Verified email at uq.edu.au
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Year
Cyclotides: from structure to function
SJ de Veer, M Kan, DJ Craik
Chemical Reviews 119, 12375-12421, 2019
1962019
Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4
JE Swedberg, LV Nigon, JC Reid, SJ de Veer, CM Walpole, CR Stephens, ...
Chemistry & Biology 16, 633-643, 2009
1452009
Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome
L Furio, S de Veer, M Jaillet, A Briot, A Robin, C Deraison, A Hovnanian
The Journal of Experimental Medicine 211, 499-513, 2014
1212014
Proteases: common culprits in human skin disorders
SJ de Veer, L Furio, JM Harris, A Hovnanian
Trends in Molecular Medicine 20, 166-178, 2014
1132014
Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network
JE Swedberg, SJ de Veer, KC Sit, CF Reboul, AM Buckle, JM Harris
PLOS One 6, e19302, 2011
852011
Selective substrates and inhibitors for kallikrein-related peptidase 7 (KLK7) shed light on KLK proteolytic activity in the stratum corneum
SJ de Veer, L Furio, JE Swedberg, CA Munro, M Brattsand, JA Clements, ...
Journal of Investigative Dermatology 137, 430-439, 2017
692017
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition
SJ de Veer, JE Swedberg, M Akcan, KJ Rosengren, M Brattsand, DJ Craik, ...
Biochemical Journal 469, 243-253, 2015
682015
A new TRPV3 missense mutation in a patient with Olmsted syndrome and erythromelalgia
S Duchatelet, S Pruvost, S de Veer, S Fraitag, P Nitschké, C Bole-Feysot, ...
JAMA Dermatology 150, 303-306, 2014
632014
Cyclotides as tools in chemical biology
SJ de Veer, J Weidmann, DJ Craik
Accounts of Chemical Research 50, 1557-1565, 2017
622017
Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library
SJ de Veer, CK Wang, JM Harris, DJ Craik, JE Swedberg
Journal of Medicinal Chemistry 58, 8257-8268, 2015
582015
Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology
SJ de Veer, AM White, DJ Craik
Angewandte Chemie International Edition 60, 8050-8071, 2021
532021
Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold
JE Swedberg, CY Li, SJ de Veer, CK Wang, DJ Craik
Journal of Medicinal Chemistry 60, 658-667, 2017
522017
Mechanism‐based selection of a potent kallikrein‐related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI‐1
SJ de Veer, SS Ukolova, CA Munro, JE Swedberg, AM Buckle, JM Harris
Peptide Science (Biopolymers) 100, 510-518, 2013
512013
Natural and engineered kallikrein inhibitors: an emerging pharmacopoeia
JE Swedberg, SJ de Veer, JM Harris
Biological Chemistry 391, 357-374, 2010
452010
Substrate-guided design of selective FXIIa inhibitors based on the plant-derived Momordica cochinchinensis trypsin inhibitor-II (MCoTI-II) scaffold
JE Swedberg, T Mahatmanto, H Abdul Ghani, SJ de Veer, CI Schroeder, ...
Journal of Medicinal Chemistry 59, 7287-7292, 2016
422016
Olmsted syndrome with erythromelalgia caused by recessive TRPV3 mutations
S Duchatelet, L Guibbal, S de Veer, S Fraitag, P Nitschké, M Zarhrate, ...
British Journal of Dermatology 171, 675-678, 2014
402014
Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
BT Riley, O Ilyichova, MGS Costa, BT Porebski, SJ de Veer, JE Swedberg, ...
Scientific Reports 6, 35385, 2016
392016
Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14
SJ de Veer, JE Swedberg, EA Parker, JM Harris
Biological Chemistry 393, 331-341, 2012
382012
Enzymatic C-terminal protein engineering with amines
FBH Rehm, TJ Tyler, K Yap, SJ de Veer, DJ Craik, T Durek
Journal of the American Chemical Society 143, 19498-19504, 2021
372021
Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors
SJ de Veer, JE Swedberg, M Brattsand, JA Clements, JM Harris
Biological Chemistry 397, 1237-1249, 2016
362016
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