Cyclotides: from structure to function SJ de Veer, M Kan, DJ Craik Chemical Reviews 119, 12375-12421, 2019 | 196 | 2019 |
Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4 JE Swedberg, LV Nigon, JC Reid, SJ de Veer, CM Walpole, CR Stephens, ... Chemistry & Biology 16, 633-643, 2009 | 145 | 2009 |
Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome L Furio, S de Veer, M Jaillet, A Briot, A Robin, C Deraison, A Hovnanian The Journal of Experimental Medicine 211, 499-513, 2014 | 121 | 2014 |
Proteases: common culprits in human skin disorders SJ de Veer, L Furio, JM Harris, A Hovnanian Trends in Molecular Medicine 20, 166-178, 2014 | 113 | 2014 |
Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network JE Swedberg, SJ de Veer, KC Sit, CF Reboul, AM Buckle, JM Harris PLOS One 6, e19302, 2011 | 85 | 2011 |
Selective substrates and inhibitors for kallikrein-related peptidase 7 (KLK7) shed light on KLK proteolytic activity in the stratum corneum SJ de Veer, L Furio, JE Swedberg, CA Munro, M Brattsand, JA Clements, ... Journal of Investigative Dermatology 137, 430-439, 2017 | 69 | 2017 |
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition SJ de Veer, JE Swedberg, M Akcan, KJ Rosengren, M Brattsand, DJ Craik, ... Biochemical Journal 469, 243-253, 2015 | 68 | 2015 |
A new TRPV3 missense mutation in a patient with Olmsted syndrome and erythromelalgia S Duchatelet, S Pruvost, S de Veer, S Fraitag, P Nitschké, C Bole-Feysot, ... JAMA Dermatology 150, 303-306, 2014 | 63 | 2014 |
Cyclotides as tools in chemical biology SJ de Veer, J Weidmann, DJ Craik Accounts of Chemical Research 50, 1557-1565, 2017 | 62 | 2017 |
Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library SJ de Veer, CK Wang, JM Harris, DJ Craik, JE Swedberg Journal of Medicinal Chemistry 58, 8257-8268, 2015 | 58 | 2015 |
Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology SJ de Veer, AM White, DJ Craik Angewandte Chemie International Edition 60, 8050-8071, 2021 | 53 | 2021 |
Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold JE Swedberg, CY Li, SJ de Veer, CK Wang, DJ Craik Journal of Medicinal Chemistry 60, 658-667, 2017 | 52 | 2017 |
Mechanism‐based selection of a potent kallikrein‐related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI‐1 SJ de Veer, SS Ukolova, CA Munro, JE Swedberg, AM Buckle, JM Harris Peptide Science (Biopolymers) 100, 510-518, 2013 | 51 | 2013 |
Natural and engineered kallikrein inhibitors: an emerging pharmacopoeia JE Swedberg, SJ de Veer, JM Harris Biological Chemistry 391, 357-374, 2010 | 45 | 2010 |
Substrate-guided design of selective FXIIa inhibitors based on the plant-derived Momordica cochinchinensis trypsin inhibitor-II (MCoTI-II) scaffold JE Swedberg, T Mahatmanto, H Abdul Ghani, SJ de Veer, CI Schroeder, ... Journal of Medicinal Chemistry 59, 7287-7292, 2016 | 42 | 2016 |
Olmsted syndrome with erythromelalgia caused by recessive TRPV3 mutations S Duchatelet, L Guibbal, S de Veer, S Fraitag, P Nitschké, M Zarhrate, ... British Journal of Dermatology 171, 675-678, 2014 | 40 | 2014 |
Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics BT Riley, O Ilyichova, MGS Costa, BT Porebski, SJ de Veer, JE Swedberg, ... Scientific Reports 6, 35385, 2016 | 39 | 2016 |
Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14 SJ de Veer, JE Swedberg, EA Parker, JM Harris Biological Chemistry 393, 331-341, 2012 | 38 | 2012 |
Enzymatic C-terminal protein engineering with amines FBH Rehm, TJ Tyler, K Yap, SJ de Veer, DJ Craik, T Durek Journal of the American Chemical Society 143, 19498-19504, 2021 | 37 | 2021 |
Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors SJ de Veer, JE Swedberg, M Brattsand, JA Clements, JM Harris Biological Chemistry 397, 1237-1249, 2016 | 36 | 2016 |