Parallel Synthesis of a Library of Benzoxazoles and Benzothiazoles Using Ligand-Accelerated Copper-Catalyzed Cyclizations of ortho-Halobenzanilides G Evindar, RA Batey The Journal of Organic Chemistry 71 (5), 1802-1808, 2006 | 629 | 2006 |
Copper-catalyzed domino annulation approaches to the synthesis of benzoxazoles under microwave-accelerated and conventional thermal conditions RD Viirre, G Evindar, RA Batey The Journal of organic chemistry 73 (9), 3452-3459, 2008 | 309 | 2008 |
Copper-and palladium-catalyzed intramolecular aryl guanidinylation: an efficient method for the synthesis of 2-aminobenzimidazoles G Evindar, RA Batey Organic Letters 5 (2), 133-136, 2003 | 281 | 2003 |
Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3 JS Disch, G Evindar, CH Chiu, CA Blum, H Dai, L Jin, E Schuman, ... Journal of medicinal chemistry 56 (9), 3666-3679, 2013 | 206 | 2013 |
Copper-and palladium-catalyzed intramolecular C–S bond formation: a convenient synthesis of 2-aminobenzothiazoles LL Joyce, G Evindar, RA Batey Chemical communications, 446-447, 2004 | 125 | 2004 |
Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium … L Encinas, H O’Keefe, M Neu, MJ Remuiñán, AM Patel, A Guardia, ... Journal of Medicinal Chemistry 57 (4), 1276-1288, 2014 | 121 | 2014 |
Stereoselective synthesis of threo and erythro β-hydroxy and β-disubstituted-β-hydroxy α-amino acids MA Blaskovich, G Evindar, NGW Rose, S Wilkinson, Y Luo, GA Lajoie The Journal of Organic Chemistry 63 (11), 3631-3646, 1998 | 116 | 1998 |
Application of encoded library technology (ELT) to a protein–protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1 … CS Kollmann, X Bai, CH Tsai, H Yang, KE Lind, SR Skinner, Z Zhu, ... Bioorganic & Medicinal Chemistry 22 (7), 2353-2365, 2014 | 96 | 2014 |
Design and application of a DNA-encoded macrocyclic peptide library Z Zhu, A Shaginian, LSC Grady, T O’Keeffe, XE Shi, CP Davie, ... ACS Chemical Biology 13 (1), 53-59, 2018 | 94 | 2018 |
The discovery of VX-745: A novel and selective p38α kinase inhibitor JP Duffy, EM Harrington, FG Salituro, JE Cochran, J Green, H Gao, ... ACS Medicinal Chemistry Letters 2 (10), 758-763, 2011 | 89 | 2011 |
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening CA Machutta, CS Kollmann, KE Lind, X Bai, PF Chan, J Huang, L Ballell, ... Nature communications 8 (1), 16081, 2017 | 73 | 2017 |
Discovery of a potent class of PI3Kα inhibitors with unique binding mode via encoded library technology (ELT) H Yang, PF Medeiros, K Raha, P Elkins, KE Lind, R Lehr, ND Adams, ... ACS medicinal chemistry letters 6 (5), 531-536, 2015 | 71 | 2015 |
DNA-encoded library technology-based discovery, lead optimization, and prodrug strategy toward structurally unique indoleamine 2, 3-dioxygenase-1 (IDO1) Inhibitors WM Kazmierski, B Xia, J Miller, M De la Rosa, D Favre, RM Dunham, ... Journal of Medicinal Chemistry 63 (7), 3552-3562, 2020 | 53 | 2020 |
Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity G Evindar, H Deng, B Morgan US Patent App. 11/349,069, 2006 | 38 | 2006 |
Discovery and characterization of a class of pyrazole inhibitors of bacterial undecaprenyl pyrophosphate synthase N Concha, J Huang, X Bai, A Benowitz, P Brady, LSC Grady, LH Kryn, ... Journal of Medicinal Chemistry 59 (15), 7299-7304, 2016 | 37 | 2016 |
Peptide heterocycle conjugates: A diverted Edman degradation protocol for the synthesis of N-terminal 2-iminohydantoins G Evindar, RA Batey Organic Letters 5 (8), 1201-1204, 2003 | 37 | 2003 |
Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity AK Saha, MJ Kavarana, G Evindar, AL Satz, B Morgan US Patent 7,241,812, 2007 | 36 | 2007 |
Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity AK Saha, MJ Kavarana, G Evindar, AL Satz, B Morgan US Patent 7,241,812, 2007 | 36 | 2007 |
Inhibitors of p38 F Salituro, G Bemis, H Gao, G Evindar US Patent 6,635,644, 2003 | 35 | 2003 |
Recent developments in the synthesis of nitrogen-containing heterocycles through C–H/N–h bond functionalizations and oxidative cyclization X Liu, Y Huang, X Meng, J Li, D Wang, Y Chen, D Tang, B Chen Synlett 30 (09), 1026-1036, 2019 | 32 | 2019 |