SMAD4 and the TGFβ pathway in patients with pancreatic ductal adenocarcinoma J Dardare, A Witz, JL Merlin, P Gilson, A Harlé International journal of molecular sciences 21 (10), 3534, 2020 | 84 | 2020 |
Dihydropyrimidine dehydrogenase (DPD) deficiency screening and securing of fluoropyrimidine-based chemotherapies: update and recommendations of the French GPCO-Unicancer and … MA Loriot, J Ciccolini, F Thomas, C Barin-Le-Guellec, B Royer, G Milano, ... Bulletin du cancer 105 (4), 397-407, 2018 | 83 | 2018 |
Representative sequencing: unbiased sampling of solid tumor tissue K Litchfield, S Stanislaw, L Spain, LL Gallegos, A Rowan, D Schnidrig, ... Cell reports 31 (5), 2020 | 59 | 2020 |
Deciphering tumour heterogeneity: From tissue to liquid biopsy P Gilson, JL Merlin, A Harlé Cancers 14 (6), 1384, 2022 | 45 | 2022 |
Detection of microsatellite instability: state of the art and future applications in circulating tumour DNA (ctDNA) P Gilson, JL Merlin, A Harlé Cancers 13 (7), 1491, 2021 | 44 | 2021 |
Analysis of PIK3CA exon 9 and 20 mutations in breast cancers using PCR-HRM and PCR-ARMS: correlation with clinicopathological criteria A Harle, M Lion, N Lozano, M Husson, V Harter, P Genin, JL Merlin Oncology reports 29 (3), 1043-1052, 2013 | 43 | 2013 |
Detection of BRAF Mutations Using a Fully Automated Platform and Comparison with High Resolution Melting, Real-Time Allele Specific Amplification … A Harlé, J Salleron, C Franczak, C Dubois, P Filhine-Tressarieu, A Leroux, ... PLoS One 11 (4), e0153576, 2016 | 41 | 2016 |
Comparison of COBAS 4800 KRAS, TaqMan PCR and High Resolution Melting PCR assays for the detection of KRAS somatic mutations in formalin-fixed paraffin … A Harlé, B Busser, M Rouyer, V Harter, P Genin, A Leroux, JL Merlin Virchows Archiv 462, 329-335, 2013 | 41 | 2013 |
Evaluation of 3 molecular-based assays for microsatellite instability detection in formalin-fixed tissues of patients with endometrial and colorectal cancers P Gilson, J Levy, M Rouyer, J Demange, M Husson, C Bonnet, J Salleron, ... Scientific reports 10 (1), 16386, 2020 | 39 | 2020 |
Optimization of routine KRAS mutation PCR‐based testing procedure for rational individualized first‐line‐targeted therapy selection in metastatic colorectal cancer AS Chretien, A Harle, M Meyer‐Lefebvre, M Rouyer, M Husson, ... Cancer medicine 2 (1), 11-20, 2013 | 33 | 2013 |
Technical considerations for circulating tumor DNA detection in oncology C Franczak, P Filhine-Tresarrieu, P Gilson, JL Merlin, L Au, A Harlé Expert review of molecular diagnostics 19 (2), 121-135, 2019 | 32 | 2019 |
Emerging roles of DDB2 in cancer P Gilson, G Drouot, A Witz, JL Merlin, P Becuwe, A Harlé International Journal of Molecular Sciences 20 (20), 5168, 2019 | 31 | 2019 |
A NGS-based blood test for the diagnosis of invasive HPV-associated carcinomas with extensive viral genomic characterization X Sastre-Garau, M Diop, F Martin, G Dolivet, F Marchal, ... Clinical Cancer Research 27 (19), 5307-5316, 2021 | 29 | 2021 |
Evaluation and validation of HPV real-time PCR assay for the detection of HPV DNA in oral cytobrush and FFPE samples A Harlé, J Guillet, J Thomas, X Sastre-Garau, M Rouyer, C Ramacci, ... Scientific Reports 8 (1), 11313, 2018 | 29 | 2018 |
Rare RAS Mutations in Metastatic Colorectal Cancer Detected During Routine RAS Genotyping Using Next Generation Sequencing A Harlé, P Filhine-Tresarrieu, M Husson, R Boidot, M Rouyer, C Dubois, ... Targeted oncology 11, 363-370, 2016 | 27 | 2016 |
Comparison of pathogenicity prediction tools on somatic variants V Suybeng, F Koeppel, A Harlé, E Rouleau The Journal of Molecular Diagnostics 22 (12), 1383-1392, 2020 | 25 | 2020 |
Dépistage du déficit en dihydropyrimidine déshydrogénase (DPD) et sécurisation des chimiothérapies à base de fluoropyrimidines: mise au point et recommandations nationales du … MA Loriot, J Ciccolini, F Thomas, C Barin-Le-Guellec, B Royer, G Milano, ... Bulletin du Cancer 105 (4), 397-407, 2018 | 23 | 2018 |
Beside P53 and PTEN: Identification of molecular alterations of the RAS/MAPK and PI3K/AKT signaling pathways in high-grade serous ovarian carcinomas to determine potential … S Chen, E Cavazza, C Barlier, J Salleron, P Filhine‑Tresarrieu, C Gavoille, ... Oncology Letters 12 (5), 3264-3272, 2016 | 23 | 2016 |
Evaluation of KRAS, NRAS and BRAF hotspot mutations detection for patients with metastatic colorectal cancer using direct DNA pipetting in a fully-automated … P Gilson, C Franczak, L Dubouis, M Husson, M Rouyer, J Demange, ... PLoS One 14 (7), e0219204, 2019 | 21 | 2019 |
Expression and activation of P38 MAP kinase in invasive ductal breast cancers: correlation with expression of the estrogen receptor, HER2 and downstream signaling … JL Merlin, A Harlé, M Lion, C Ramacci, A Leroux Oncology reports 30 (4), 1943-1948, 2013 | 21 | 2013 |