Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes EO Johnson, E LaVerriere, E Office, M Stanley, E Meyer, T Kawate, ... Nature 571 (7763), 72-78, 2019 | 115 | 2019 |
Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation J Boehringer, C Riedinger, K Paraskevopoulos, EOD Johnson, ED Lowe, ... Biochemical Journal 448 (1), 55-65, 2012 | 78 | 2012 |
Selective oxidative demethylation of veratric acid to vanillic acid by CYP199A4 from Rhodopseudomonas palustris HaA2 SG Bell, ABH Tan, EOD Johnson, LL Wong Molecular BioSystems 6 (1), 206-214, 2009 | 75 | 2009 |
Protein recognition in ferredoxin–P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris SG Bell, F Xu, EOD Johnson, IM Forward, M Bartlam, Z Rao, LL Wong JBIC Journal of Biological Inorganic Chemistry 15, 315-328, 2010 | 64 | 2010 |
The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site SG Bell, W Yang, ABH Tan, R Zhou, EOD Johnson, A Zhang, W Zhou, ... Dalton Transactions 41 (28), 8703-8714, 2012 | 54 | 2012 |
Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris F Xu, SG Bell, Y Peng, EOD Johnson, M Bartlam, Z Rao, LL Wong Proteins: Structure, Function, and Bioinformatics 77 (4), 867-880, 2009 | 45 | 2009 |
Tailoring an alien ferredoxin to support native-like P450 monooxygenase activity SG Bell, JHC McMillan, JA Yorke, E Kavanagh, EOD Johnson, LL Wong Chemical communications 48 (95), 11692-11694, 2012 | 33 | 2012 |
A structural model of a P450-ferredoxin complex from orientation-selective double electron–electron resonance spectroscopy AM Bowen, EOD Johnson, F Mercuri, NJ Hoskins, R Qiao, ... Journal of the American Chemical Society 140 (7), 2514-2527, 2018 | 22 | 2018 |
Large-Scale Chemical-Genetic Strategy Enables the Design of Antimicrobial Combination Chemotherapy in Mycobacteria EO Johnson, E Office, T Kawate, M Orzechowski, DT Hung ACS infectious diseases, 2019 | 16* | 2019 |
Partial fusion of a cytochrome P450 system by carboxy-terminal attachment of putidaredoxin reductase to P450cam (CYP101A1) EOD Johnson, LL Wong Catalysis science & technology 6 (20), 7549-7560, 2016 | 13 | 2016 |
A point of inflection and reflection on systems chemical biology EO Johnson, DT Hung ACS Chemical Biology 14 (12), 2497-2511, 2019 | 12 | 2019 |
Evolution of Mycobacterium tuberculosis drug resistance in the genomic era C Nimmo, J Millard, V Faulkner, J Monteserin, H Pugh, EO Johnson Frontiers in Cellular and Infection Microbiology 12, 954074, 2022 | 10 | 2022 |
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference** J El Bakali, M Blaszczyk, JC Evans, JA Boland, WJ McCarthy, I Fathoni, ... Angewandte Chemie 135 (17), e202300221, 2023 | 5 | 2023 |
Multiplex high-resolution detection of micro-organism strains, related kits, diagnostics methods and screening assays D Hung, E Johnson, B Poulsen US Patent App. WO2017079699A1, 2017 | 2 | 2017 |
Using proteolytic hypomorphs to detect small molecule mechanism of action EO Johnson, DT Hung Mycobacteria Protocols, 323-342, 2021 | 1 | 2021 |
Developing a Platform to Evaluate Mycobacterial Drug Resistance Through Inducible Knockdown and Complementation of Essential and Non-essential Genes C Nimmo, V Faulkner, J Evans, E Johnson C107. MICROBIAL RESPIRATORY INFECTIONS DISCOVERIES, A6810-A6810, 2024 | | 2024 |
Protein-protein recognition in biological systems exhibiting highly-conserved tertiary structure: cytochrome P450 E Johnson, EOD Johnson University of Oxford, 2013 | | 2013 |