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Gopal Dahal
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Structure of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans
G Dahal, RE Viola
Acta Crystallographica Section F: Structural Biology Communications 71 (11 …, 2015
162015
Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus
GP Dahal, RE Viola
Acta Crystallographica Section F: Structural Biology Communications 73 (1 …, 2017
132017
Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase
GP Dahal, RE Viola
Biochemical and biophysical research communications 503 (4), 2848-2854, 2018
122018
Structural insights into the tetrameric state of aspartate-β-semialdehyde dehydrogenases from fungal species
Q Li, Z Mu, R Zhao, G Dahal, RE Viola, T Liu, Q Jin, S Cui
Scientific reports 6 (1), 21067, 2016
122016
Aspartate semialdehyde dehydrogenase inhibition suppresses the growth of the pathogenic fungus Candida albicans
GP Dahal, D Launder, KMM McKeone, JP Hunter, HR Conti, RE Viola
Drug Development Research 81 (6), 736-744, 2020
112020
A fragment library screening approach to identify selective inhibitors against an essential fungal enzyme
GP Dahal, RE Viola
SLAS DISCOVERY: Advancing Life Sciences R&D 23 (6), 520-531, 2018
92018
Development of bisubstrate analog inhibitors of aspartate N‐acetyltransferase, a critical brain enzyme
V Mutthamsetty, GP Dahal, Q Wang, RE Viola
Chemical Biology & Drug Design 95 (1), 48-57, 2020
52020
Crystal structures and small angle x-ray scattering analysis of antifungal drug target aspartate semialdehyde dehydrogenase
GP Dahal, S Qian, RE Viola
Acta Crystallographica Section A Foundations and Advances 73 (a1), a155-A155, 2017
12017
Structural and inhibitor screening studies of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans
GP Dahal, RE Viola
The FASEB Journal 30, 607.1-607.1, 2016
12016
Development of Selective Inhibitors against Enzymes Involved in the Aspartate Biosynthetic Pathway for Antifungal Drug Development
GP Dahal
The University of Toledo, 2018
2018
Structural and inhibitor development studies of fungal forms of aspartate semialdehyde dehydrogenase
G Dahal, R Viola
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
Structure of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus
G Dahal, RE Viola
2015
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