| TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS CH Yu, S Davidson, CR Harapas, JB Hilton, MJ Mlodzianoski, ... Cell 183 (3), 636-649. e18, 2020 | 517 | 2020 |
| Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding FL Zhong, K Robinson, DET Teo, KY Tan, C Lim, CR Harapas, CH Yu, ... Journal of Biological Chemistry 293 (49), 18864-18878, 2018 | 189 | 2018 |
| T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles SC Law, S Street, CHA Yu, C Capini, S Ramnoruth, HJ Nel, E van Gorp, ... Arthritis research & therapy 14, 1-12, 2012 | 166 | 2012 |
| NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease H Tye, CH Yu, LA Simms, MR de Zoete, ML Kim, M Zakrzewski, ... Nature communications 9 (1), 3728, 2018 | 103 | 2018 |
| Mechanisms of NLRP1-mediated autoinflammatory disease in humans and mice CH Yu, J Moecking, M Geyer, SL Masters Journal of molecular biology 430 (2), 142-152, 2018 | 89 | 2018 |
| Organellar homeostasis and innate immune sensing CR Harapas, E Idiiatullina, M Al-Azab, K Hrovat-Schaale, T Reygaerts, ... Nature Reviews Immunology 22 (9), 535-549, 2022 | 49 | 2022 |
| Deficiency in coatomer complex I causes aberrant activation of STING signalling A Steiner, K Hrovat-Schaale, I Prigione, CH Yu, P Laohamonthonkul, ... Nature communications 13 (1), 2321, 2022 | 42 | 2022 |
| Recombinant W nt3a and W nt5a elicit macrophage cytokine production and tolerization to microbial stimulation via T oll‐like receptor 4 CH Yu, TTK Nguyen, KM Irvine, MJ Sweet, IH Frazer, A Blumenthal European journal of immunology 44 (5), 1480-1490, 2014 | 40 | 2014 |
| Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24 S Davidson, CH Yu, A Steiner, F Ebstein, PJ Baker, V Jarur-Chamy, ... Science Immunology 7 (68), eabi6763, 2022 | 28 | 2022 |
| RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection CH Yu, M Micaroni, A Puyskens, TE Schultz, JC Yeo, AC Stanley, ... The Journal of Immunology 195 (8), 3890-3900, 2015 | 28 | 2015 |
| DPP9 deficiency: an inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling CR Harapas, KS Robinson, K Lay, J Wong, R Moreno Traspas, ... Science immunology 7 (75), eabi4611, 2022 | 22 | 2022 |
| Activation of STING due to COPI-deficiency A Steiner, KH Schaale, I Prigione, D De Nardo, LF Dagley, CH Yu, ... BioRxiv, 2020.07. 09.194399, 2020 | 17 | 2020 |
| NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity J Moecking, P Laohamonthonkul, K Chalker, MJ White, CR Harapas, ... Journal of Allergy and Clinical Immunology 147 (6), 2134-2145. e20, 2021 | 15 | 2021 |
| Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection LC Domínguez Cadena, TE Schultz, A Zamoshnikova, ML Donovan, ... Immunology and Cell Biology 99 (10), 1067-1076, 2021 | 2 | 2021 |
| DPP9 is an endogenous and direct inhibitor of the NLRP1 inflammasome that guards against human auto-inflammatory diseases FL Zhong, K Robinson, C Lim, CR Harapas, CH Yu, W Xie, RM Sobota, ... bioRxiv, 260919, 2018 | 1 | 2018 |
| Stray self-nucleic acids: the emerging drivers of neurodegeneration BK McDonald, P Laohamonthonkul, CH Yu Trends in Cell Biology, 2023 | | 2023 |
| Methods of Treatment, Prevention and Diagnosis S Masters, CH Yu US Patent App. 17/290,187, 2022 | | 2022 |
