Marcel Hoefnagel
Marcel Hoefnagel
Senior Assessor Biopharmaceuticals, Medicines Evaluation Board, Utrecht, The Netherlands
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Interdependence between chloroplasts and mitochondria in the light and the dark
MHN Hoefnagel, OK Atkin, JT Wiskich
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1366 (3), 235-255, 1998
Effects of cultivation conditions on folate production by lactic acid bacteria
W Sybesma, M Starrenburg, L Tijsseling, MHN Hoefnagel, J Hugenholtz
Applied and environmental microbiology 69 (8), 4542-4548, 2003
Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysisThe GenBank accession number for the …
MHN Hoefnagel, MJC Starrenburg, DE Martens, J Hugenholtz, ...
Microbiology 148 (4), 1003-1013, 2002
Cytochrome and alternative respiratory pathways compete for electrons in the presence of pyruvate in soybean mitochondria
MHN Hoefnagel, AH Millar, JT Wiskich, DA Day
Archives of Biochemistry and Biophysics 318 (2), 394-400, 1995
Specificity of the organic acid activation of alternative oxidase in plant mitochondria
AH Millar, MHN Hoefnagel, DA Day, JT Wiskich
Plant Physiology 111 (2), 613-618, 1996
High-level acetaldehyde production in Lactococcus lactis by metabolic engineering
RS Bongers, MHN Hoefnagel, M Kleerebezem
Applied and environmental microbiology 71 (2), 1109-1113, 2005
IS981-mediated adaptive evolution recovers lactate production by ldhB transcription activation in a lactate dehydrogenase-deficient strain of Lactococcus lactis
RS Bongers, MHN Hoefnagel, MJC Starrenburg, MAJ Siemerink, ...
Journal of bacteriology 185 (15), 4499-4507, 2003
Challenges in the implementation of EAACI guidelines on allergen immunotherapy: a global perspective on the regulation of allergen products
A Bonertz, GC Roberts, M Hoefnagel, M Timon, JE Slater, RL Rabin, ...
Allergy 73 (1), 64-76, 2018
Allergen manufacturing and quality aspects for allergen immunotherapy in Europe and the United States: an analysis from the EAACI AIT Guidelines Project
A Bonertz, G Roberts, JE Slater, J Bridgewater, RL Rabin, M Hoefnagel, ...
Allergy 73 (4), 816-826, 2018
Activation of the plant alternative oxidase by high reduction levels of the Q-pool and pyruvate
MHN Hoefnagel, JT Wiskich
Archives of Biochemistry and Biophysics 355 (2), 262-270, 1998
Overproduction of heterologous mannitol 1-phosphatase: a key factor for engineering mannitol production by Lactococcus lactis
HW Wisselink, APHA Moers, AE Mars, MHN Hoefnagel, WM De Vos, ...
Applied and environmental microbiology 71 (3), 1507-1514, 2005
Time dependent responses of glycolytic intermediates in a detailed glycolytic model of Lactococcus lactis during glucose run-out experiments
MHN Hoefnagel, A Van Der Burgt, DE Martens, J Hugenholtz, JL Snoep
Molecular biology reports 29 (1), 157-161, 2002
Spontaneous formation of a mannitol-producing variant of Leuconostoc pseudomesenteroides grown in the presence of fructose
GJ Grobben, SWPG Peters, HW Wisselink, RA Weusthuis, ...
Applied and environmental microbiology 67 (6), 2867-2870, 2001
A single amino acid change in the plant alternative oxidase alters the specificity of organic acid activation
I Djajanegara, R Holtzapffel, PM Finnegan, MHN Hoefnagel, DA Berthold, ...
FEBS letters 454 (3), 220-224, 1999
Substrate kinetics of the plant mitochondrial alternative oxidase and the effects of pyruvate
MHN Hoefnagel, PR Rich, Q Zhang, JT Wiskich
Plant physiology 115 (3), 1145-1153, 1997
Regulatory perspective on in vitro potency assays for human mesenchymal stromal cells used in immunotherapy
C De Wolf, M Van De Bovenkamp, M Hoefnagel
Cytotherapy 19 (7), 784-797, 2017
New inhibitors of the ubiquinol oxidase of higher plant mitochondria
MHN Hoefnagel, JT Wiskich, SA Madgwick, Z Patterson, W Oettmeier, ...
European journal of biochemistry 233 (2), 531-537, 1995
In support of the European Union biosimilar framework
CK Schneider, JJ Borg, F Ehmann, N Ekman, E Heinonen, K Ho, ...
Nature biotechnology 30 (8), 745-748, 2012
Alternative oxidase from Arum and soybean: Its stabilization during purification
Q Zhang, MHN Hoefnagel, JT Wiskich
Physiologia Plantarum 96 (4), 551-558, 1996
In suspension cultures of Catharanthus roseus the cyanide‐resistant pathway is engaged in respiration by excess sugar in combination with phosphate or nitrogen starvation
MHN Hoefnagel, F Van Iren, KR Libbenga
Physiologia Plantarum 87 (3), 297-304, 1993
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