Luigi Bubacco
Luigi Bubacco
Dipartimento di Biologia , UniversitÓ degli Studi di Padova, Italy
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Triggering of inflammasome by aggregated α–synuclein, an inflammatory response in synucleinopathies
G Codolo, N Plotegher, T Pozzobon, M Brucale, I Tessari, L Bubacco, ...
PloS one 8 (1), 2013
Kinetic and structural analysis of the early oxidation products of dopamine analysis of the interactions with α-synuclein
M Bisaglia, S Mammi, L Bubacco
Journal of Biological Chemistry 282 (21), 15597-15605, 2007
Conformational equilibria in monomeric α-synuclein at the single-molecule level
M Sandal, F Valle, I Tessari, S Mammi, E Bergantino, F Musiani, ...
PLoS biology 6 (1), 2008
Structural insights on physiological functions and pathological effects of α-synuclein
M Bisaglia, S Mammi, L Bubacco
The FASEB Journal 23 (2), 329-340, 2009
A topological model of the interaction between α-synuclein and sodium dodecyl sulfate micelles
M Bisaglia, I Tessari, L Pinato, M Bellanda, S Giraudo, M Fasano, ...
Biochemistry 44 (1), 329-339, 2005
LRRK2 and neuroinflammation: partners in crime in Parkinson’s disease?
I Russo, L Bubacco, E Greggio
Journal of neuroinflammation 11 (1), 52, 2014
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2
A Biosa, A Trancikova, L Civiero, L Glauser, L Bubacco, E Greggio, ...
Human molecular genetics 22 (6), 1140-1156, 2013
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease
E Greggio, E Bergantino, D Carter, R Ahmad, GE Costin, VJ Hearing, ...
Journal of neurochemistry 93 (1), 246-256, 2005
Dopamine quinones interact with α-synuclein to form unstructured adducts
M Bisaglia, L Tosatto, F Munari, I Tessari, PP de Laureto, S Mammi, ...
Biochemical and biophysical research communications 394 (2), 424-428, 2010
Broken helix in vesicle and micelle-bound α-synuclein: Insights from site-directed spin labeling-EPR experiments and MD simulations
M Bortolus, F Tombolato, I Tessari, M Bisaglia, S Mammi, L Bubacco, ...
Journal of the American Chemical Society 130 (21), 6690-6691, 2008
The reaction of α-synuclein with tyrosinase possible implications for parkinson disease
I Tessari, M Bisaglia, F Valle, B Samorý, E Bergantino, S Mammi, ...
Journal of Biological Chemistry 283 (24), 16808-16817, 2008
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers
L Civiero, R Vancraenenbroeck, E Belluzzi, A Beilina, E Lobbestael, ...
PloS one 7 (8), 2012
Pathogenic Mutations Shift the Equilibria of α‐Synuclein Single Molecules towards Structured Conformers
M Brucale, M Sandal, S Di Maio, A Rampioni, I Tessari, L Tosatto, ...
Chembiochem 10 (1), 176-183, 2009
Tyrosinase-catalyzed oxidation of fluorophenols
G Battaini, E Monzani, L Casella, E Lonardi, AWJW Tepper, GW Canters, ...
Journal of Biological Chemistry 277 (47), 44606-44612, 2002
1H NMR spectroscopy of the binuclear Cu (II) active site of Streptomyces antibioticus tyrosinase
L Bubacco, J Salgado, AWJW Tepper, E Vijgenboom, GW Canters
FEBS letters 442 (2-3), 215-220, 1999
Exosomes-associated neurodegeneration and progression of Parkinson’s disease
I Russo, L Bubacco, E Greggio
American journal of neurodegenerative disease 1 (3), 217, 2012
Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: implications for mitochondrial dysfunction in Parkinson disease
M Bisaglia, ME Soriano, I Arduini, S Mammi, L Bubacco
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (9), 699-706, 2010
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex
MD Cirnaru, A Marte, E Belluzzi, I Russo, M Gabrielli, F Longo, L Arcuri, ...
Frontiers in molecular neuroscience 7, 49, 2014
Structural and morphological characterization of aggregated species of α-synuclein induced by docosahexaenoic acid
G De Franceschi, E Frare, M Pivato, A Relini, A Penco, E Greggio, ...
Journal of Biological Chemistry 286 (25), 22262-22274, 2011
Alpha-synuclein pore forming activity upon membrane association
L Tosatto, AO Andrighetti, N Plotegher, V Antonini, I Tessari, L Ricci, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (11), 2876-2883, 2012
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