Structural basis of low-pH-dependent lysosomal cholesterol egress by NPC1 and NPC2 H Qian, X Wu, X Du, X Yao, X Zhao, J Lee, H Yang, N Yan Cell 182 (1), 98-111. e18, 2020 | 126 | 2020 |
A chemical approach for global protein knockdown from mice to non-human primates X Sun, J Wang, X Yao, W Zheng, Y Mao, T Lan, L Wang, Y Sun, X Zhang, ... Cell Discovery 5 (1), 10, 2019 | 115 | 2019 |
Cryo-EM analysis of a membrane protein embedded in the liposome X Yao, X Fan, N Yan Proceedings of the National Academy of Sciences 117 (31), 18497-18503, 2020 | 106 | 2020 |
Structure of human Cav2.2 channel blocked by the painkiller ziconotide S Gao, X Yao, N Yan Nature 596 (7870), 143-147, 2021 | 99 | 2021 |
Structural basis for catalysis and substrate specificity of human ACAT1 H Qian, X Zhao, R Yan, X Yao, S Gao, X Sun, X Du, H Yang, CCL Wong, ... Nature 581 (7808), 333-338, 2020 | 77 | 2020 |
Pd (ii) catalyzed ortho C–H iodination of phenylcarbamates at room temperature using cyclic hypervalent iodine reagents X Sun, X Yao, C Zhang, Y Rao Chemical communications 51 (49), 10014-10017, 2015 | 47 | 2015 |
Structural basis for pore blockade of human voltage-gated calcium channel Cav1.3 by motion sickness drug cinnarizine X Yao, S Gao, N Yan Cell Research 32 (10), 946-948, 2022 | 33 | 2022 |
Synthesis of Phosphaisoquinolin‐1‐one by Annulation of Aryl Phosphinamides with Allenes through a Cobalt‐Promoted C− H Functionalization X Yao, L Jin, Y Rao Asian Journal of Organic Chemistry 6 (7), 825-830, 2017 | 32 | 2017 |
Discovery of 4-aminoquinoline-3-carboxamide derivatives as potent reversible Bruton’s tyrosine kinase inhibitors for the treatment of rheumatoid arthritis X Yao, X Sun, S Jin, L Yang, H Xu, Y Rao Journal of Medicinal Chemistry 62 (14), 6561-6574, 2019 | 27 | 2019 |
Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels X Yao, S Gao, J Wang, Z Li, J Huang, Y Wang, Z Wang, J Chen, X Fan, ... Cell 185 (25), 4801-4810. e13, 2022 | 12 | 2022 |
Structures of the R-type human Cav2.3 channel reveal conformational crosstalk of the intracellular segments X Yao, Y Wang, Z Wang, X Fan, D Wu, J Huang, A Mueller, S Gao, M Hu, ... Nature communications 13 (1), 7358, 2022 | 11 | 2022 |
Structural basis for human Cav1. 2 inhibition by multiple drugs and the neurotoxin calciseptine S Gao, X Yao, J Chen, G Huang, X Fan, L Xue, Z Li, T Wu, Y Zheng, ... Cell 186 (24), 5363-5374. e16, 2023 | 4 | 2023 |