|Guidelines for the use and interpretation of assays for monitoring autophagy|
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
|XBP1 is essential for survival under hypoxic conditions and is required for tumor growth|
L Romero-Ramirez, H Cao, D Nelson, E Hammond, AH Lee, H Yoshida, ...
Cancer research 64 (17), 5943-5947, 2004
|Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation|
C Koumenis, R Alarcon, E Hammond, P Sutphin, W Hoffman, M Murphy, ...
Molecular and cellular biology 21 (4), 1297-1310, 2001
|Hypoxia links ATR and p53 through replication arrest|
EM Hammond, NC Denko, MJ Dorie, RT Abraham, AJ Giaccia
Molecular and cellular biology 22 (6), 1834-1843, 2002
|ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation|
EM Hammond, MJ Dorie, AJ Giaccia
Journal of Biological Chemistry 278 (14), 12207-12213, 2003
|Regulation of autophagy by ATF4 in response to severe hypoxia|
T Rzymski, M Milani, L Pike, F Buffa, HR Mellor, L Winchester, I Pires, ...
Oncogene 29 (31), 4424-4435, 2010
|Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation|
E Fokas, R Prevo, JR Pollard, PM Reaper, PA Charlton, B Cornelissen, ...
Cell death & disease 3 (12), e441-e441, 2012
|The role of p53 in hypoxia-induced apoptosis|
EM Hammond, AJ Giaccia
Biochemical and biophysical research communications 331 (3), 718-725, 2005
|ATM activation and signaling under hypoxic conditions|
Z Bencokova, MR Kaufmann, IM Pires, PS Lecane, AJ Giaccia, ...
Molecular and cellular biology 29 (2), 526-537, 2009
|Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment|
N Chan, IM Pires, Z Bencokova, C Coackley, KR Luoto, N Bhogal, ...
Cancer research 70 (20), 8045-8054, 2010
|Targeting ATR in DNA damage response and cancer therapeutics|
E Fokas, R Prevo, EM Hammond, TB Brunner, WG McKenna, RJ Muschel
Cancer treatment reviews 40 (1), 109-117, 2014
|Targeting radiation-resistant hypoxic tumour cells through ATR inhibition|
IM Pires, MM Olcina, S Anbalagan, JR Pollard, PM Reaper, PA Charlton, ...
British journal of cancer 107 (2), 291-299, 2012
|Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability|
IM Pires, Z Bencokova, M Milani, LK Folkes, JL Li, MR Stratford, AL Harris, ...
Cancer research 70 (3), 925-935, 2010
|The p53 QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality|
TM Johnson, EM Hammond, A Giaccia, LD Attardi
Nature genetics 37 (2), 145-152, 2005
|The meaning, measurement and modification of hypoxia in the laboratory and the clinic|
EM Hammond, MC Asselin, D Forster, JPB O'Connor, JM Senra, ...
Clinical oncology 26 (5), 277-288, 2014
|A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells|
K Phadwal, J Alegre-Abarrategui, AS Watson, L Pike, S Anbalagan, ...
Autophagy 8 (4), 677-689, 2012
|UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α|
Y Goto, L Zeng, CJ Yeom, Y Zhu, A Morinibu, K Shinomiya, M Kobayashi, ...
Nature communications 6 (1), 1-13, 2015
|Optimization of 3, 5-dimethylisoxazole derivatives as potent bromodomain ligands|
DS Hewings, O Fedorov, P Filippakopoulos, S Martin, S Picaud, A Tumber, ...
Journal of medicinal chemistry 56 (8), 3217-3227, 2013
|Inhibition of ATR leads to increased sensitivity to hypoxia/reoxygenation|
EM Hammond, MJ Dorie, AJ Giaccia
Cancer research 64 (18), 6556-6562, 2004
|Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast|
EM Hammond, CL Brunet, GD Johnson, J Parkhill, AE Milner, G Brady, ...
FEBS letters 425 (3), 391-395, 1998