Trevor D Lawley
TitleCited byYear
Emergence and global spread of epidemic healthcare-associated Clostridium difficile
M He, F Miyajima, P Roberts, L Ellison, DJ Pickard, MJ Martin, TR Connor, ...
Nature genetics 45 (1), 109, 2013
5382013
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice
TD Lawley, S Clare, AW Walker, MD Stares, TR Connor, C Raisen, ...
PLoS pathogens 8 (10), e1002995, 2012
4692012
Culturing of ‘unculturable’human microbiota reveals novel taxa and extensive sporulation
HP Browne, SC Forster, BO Anonye, N Kumar, BA Neville, MD Stares, ...
Nature 533 (7604), 543, 2016
4382016
F factor conjugation is a true type IV secretion system
TD Lawley, WA Klimke, MJ Gubbins, LS Frost
FEMS microbiology letters 224 (1), 1-15, 2003
3992003
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
RA Stabler, M He, L Dawson, M Martin, E Valiente, C Corton, TD Lawley, ...
Genome biology 10 (9), R102, 2009
3492009
Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse
TD Lawley, K Chan, LJ Thompson, CC Kim, GR Govoni, DM Monack
PLoS pathogens 2 (2), e11, 2006
3372006
Evolutionary dynamics of Clostridium difficile over short and long time scales
M He, M Sebaihia, TD Lawley, RA Stabler, LF Dawson, MJ Martin, KE Holt, ...
Proceedings of the National Academy of Sciences 107 (16), 7527-7532, 2010
3262010
Intestinal colonization resistance
TD Lawley, AW Walker
Immunology 138 (1), 1-11, 2013
3242013
Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts
TD Lawley, S Clare, AW Walker, D Goulding, RA Stabler, N Croucher, ...
Infection and immunity 77 (9), 3661-3669, 2009
2852009
The Clostridium difficile spo0A gene is a persistence and transmission factor
LJ Deakin, S Clare, RP Fagan, LF Dawson, DJ Pickard, MR West, ...
Infection and immunity 80 (8), 2704-2711, 2012
2272012
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota
TD Lawley, DM Bouley, YE Hoy, C Gerke, DA Relman, DM Monack
Infection and immunity 76 (1), 403-416, 2008
2152008
Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores
TD Lawley, NJ Croucher, L Yu, S Clare, M Sebaihia, D Goulding, ...
Journal of bacteriology 191 (17), 5377-5386, 2009
2102009
The complete DNA sequence and analysis of R27, a large IncHI plasmid from Salmonella typhi that is temperature sensitive for transfer
CK Sherburne, TD Lawley, MW Gilmour, FR Blattner, V Burland, ...
Nucleic acids research 28 (10), 2177-2186, 2000
1502000
Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen
TAN Pham, S Clare, D Goulding, JM Arasteh, MD Stares, HP Browne, ...
Cell host & microbe 16 (4), 504-516, 2014
1462014
Therapeutic modulation of intestinal dysbiosis
AW Walker, TD Lawley
Pharmacological Research 69 (1), 75-86, 2013
1442013
Distinct commensals induce interleukin-1β via NLRP3 inflammasome in inflammatory monocytes to promote intestinal inflammation in response to injury
SU Seo, N Kamada, R Muņoz-Planillo, YG Kim, D Kim, Y Koizumi, ...
Immunity 42 (4), 744-755, 2015
1362015
Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011
CW Knetsch, TR Connor, A Mutreja, SM Van Dorp, IM Sanders, ...
Euro surveillance: bulletin Europeen sur les maladies transmissibles …, 2014
1212014
Global analysis of the sporulation pathway of Clostridium difficile
KA Fimlaid, JP Bond, KC Schutz, EE Putnam, JM Leung, TD Lawley, ...
PLoS genetics 9 (8), e1003660, 2013
1212013
Current application and future perspectives of molecular typing methods to study Clostridium difficile infections
CW Knetsch, TD Lawley, MP Hensgens, J Corver, MW Wilcox, EJ Kuijper
Eurosurveillance 18 (4), 20381, 2013
1182013
Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during Clostridium difficile infections
GP Carter, A Chakravorty, TAP Nguyen, S Mileto, F Schreiber, L Li, ...
MBio 6 (3), e00551-15, 2015
1132015
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