Trevor D Lawley
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Emergence and global spread of epidemic healthcare-associated Clostridium difficile
M He, F Miyajima, P Roberts, L Ellison, DJ Pickard, MJ Martin, TR Connor, ...
Nature genetics 45 (1), 109-113, 2013
Culturing of ‘unculturable’human microbiota reveals novel taxa and extensive sporulation
HP Browne, SC Forster, BO Anonye, N Kumar, BA Neville, MD Stares, ...
Nature 533 (7604), 543-546, 2016
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice
TD Lawley, S Clare, AW Walker, MD Stares, TR Connor, C Raisen, ...
PLoS Pathog 8 (10), e1002995, 2012
F factor conjugation is a true type IV secretion system
TD Lawley, WA Klimke, MJ Gubbins, LS Frost
FEMS microbiology letters 224 (1), 1-15, 2003
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
RA Stabler, M He, L Dawson, M Martin, E Valiente, C Corton, TD Lawley, ...
Genome biology 10 (9), R102, 2009
Intestinal colonization resistance
TD Lawley, AW Walker
Immunology 138 (1), 1-11, 2013
Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse
TD Lawley, K Chan, LJ Thompson, CC Kim, GR Govoni, DM Monack
PLoS Pathog 2 (2), e11, 2006
Evolutionary dynamics of Clostridium difficile over short and long time scales
M He, M Sebaihia, TD Lawley, RA Stabler, LF Dawson, MJ Martin, KE Holt, ...
Proceedings of the National Academy of Sciences 107 (16), 7527-7532, 2010
Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts
TD Lawley, S Clare, AW Walker, D Goulding, RA Stabler, N Croucher, ...
Infection and immunity 77 (9), 3661-3669, 2009
The Clostridium difficile spo0A gene is a persistence and transmission factor
LJ Deakin, S Clare, RP Fagan, LF Dawson, DJ Pickard, MR West, ...
Infection and immunity 80 (8), 2704-2711, 2012
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota
TD Lawley, DM Bouley, YE Hoy, C Gerke, DA Relman, DM Monack
Infection and immunity 76 (1), 403-416, 2008
Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores
TD Lawley, NJ Croucher, L Yu, S Clare, M Sebaihia, D Goulding, ...
Journal of bacteriology 191 (17), 5377-5386, 2009
A new genomic blueprint of the human gut microbiota
A Almeida, AL Mitchell, M Boland, SC Forster, GB Gloor, A Tarkowska, ...
Nature 568 (7753), 499-504, 2019
Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen
TAN Pham, S Clare, D Goulding, JM Arasteh, MD Stares, HP Browne, ...
Cell host & microbe 16 (4), 504-516, 2014
Therapeutic modulation of intestinal dysbiosis
AW Walker, TD Lawley
Pharmacological Research 69 (1), 75-86, 2013
Distinct commensals induce interleukin-1β via NLRP3 inflammasome in inflammatory monocytes to promote intestinal inflammation in response to injury
SU Seo, N Kamada, R Muņoz-Planillo, YG Kim, D Kim, Y Koizumi, ...
Immunity 42 (4), 744-755, 2015
The complete DNA sequence and analysis of R27, a large IncHI plasmid from Salmonella typhi that is temperature sensitive for transfer
CK Sherburne, TD Lawley, MW Gilmour, FR Blattner, V Burland, ...
Nucleic acids research 28 (10), 2177-2186, 2000
Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011
CW Knetsch, TR Connor, A Mutreja, SM Van Dorp, IM Sanders, ...
Eurosurveillance 19 (45), 20954, 2014
Dietary trehalose enhances virulence of epidemic Clostridium difficile
J Collins, C Robinson, H Danhof, CW Knetsch, HC Van Leeuwen, ...
Nature 553 (7688), 291-294, 2018
Global analysis of the sporulation pathway of Clostridium difficile
KA Fimlaid, JP Bond, KC Schutz, EE Putnam, JM Leung, TD Lawley, ...
PLoS Genet 9 (8), e1003660, 2013
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