|Emergence and global spread of epidemic healthcare-associated Clostridium difficile|
M He, F Miyajima, P Roberts, L Ellison, DJ Pickard, MJ Martin, TR Connor, ...
Nature genetics 45 (1), 109, 2013
|Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice|
TD Lawley, S Clare, AW Walker, MD Stares, TR Connor, C Raisen, ...
PLoS pathogens 8 (10), e1002995, 2012
|Culturing of ‘unculturable’human microbiota reveals novel taxa and extensive sporulation|
HP Browne, SC Forster, BO Anonye, N Kumar, BA Neville, MD Stares, ...
Nature 533 (7604), 543, 2016
|F factor conjugation is a true type IV secretion system|
TD Lawley, WA Klimke, MJ Gubbins, LS Frost
FEMS microbiology letters 224 (1), 1-15, 2003
|Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium|
RA Stabler, M He, L Dawson, M Martin, E Valiente, C Corton, TD Lawley, ...
Genome biology 10 (9), R102, 2009
|Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse|
TD Lawley, K Chan, LJ Thompson, CC Kim, GR Govoni, DM Monack
PLoS pathogens 2 (2), e11, 2006
|Evolutionary dynamics of Clostridium difficile over short and long time scales|
M He, M Sebaihia, TD Lawley, RA Stabler, LF Dawson, MJ Martin, KE Holt, ...
Proceedings of the National Academy of Sciences 107 (16), 7527-7532, 2010
|Intestinal colonization resistance|
TD Lawley, AW Walker
Immunology 138 (1), 1-11, 2013
|Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts|
TD Lawley, S Clare, AW Walker, D Goulding, RA Stabler, N Croucher, ...
Infection and immunity 77 (9), 3661-3669, 2009
|The Clostridium difficile spo0A gene is a persistence and transmission factor|
LJ Deakin, S Clare, RP Fagan, LF Dawson, DJ Pickard, MR West, ...
Infection and immunity 80 (8), 2704-2711, 2012
|Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota|
TD Lawley, DM Bouley, YE Hoy, C Gerke, DA Relman, DM Monack
Infection and immunity 76 (1), 403-416, 2008
|Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores|
TD Lawley, NJ Croucher, L Yu, S Clare, M Sebaihia, D Goulding, ...
Journal of bacteriology 191 (17), 5377-5386, 2009
|The complete DNA sequence and analysis of R27, a large IncHI plasmid from Salmonella typhi that is temperature sensitive for transfer|
CK Sherburne, TD Lawley, MW Gilmour, FR Blattner, V Burland, ...
Nucleic acids research 28 (10), 2177-2186, 2000
|Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen|
TAN Pham, S Clare, D Goulding, JM Arasteh, MD Stares, HP Browne, ...
Cell host & microbe 16 (4), 504-516, 2014
|Therapeutic modulation of intestinal dysbiosis|
AW Walker, TD Lawley
Pharmacological Research 69 (1), 75-86, 2013
|Distinct commensals induce interleukin-1β via NLRP3 inflammasome in inflammatory monocytes to promote intestinal inflammation in response to injury|
SU Seo, N Kamada, R Muņoz-Planillo, YG Kim, D Kim, Y Koizumi, ...
Immunity 42 (4), 744-755, 2015
|Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011|
CW Knetsch, TR Connor, A Mutreja, SM Van Dorp, IM Sanders, ...
Euro surveillance: bulletin Europeen sur les maladies transmissibles …, 2014
|Global analysis of the sporulation pathway of Clostridium difficile|
KA Fimlaid, JP Bond, KC Schutz, EE Putnam, JM Leung, TD Lawley, ...
PLoS genetics 9 (8), e1003660, 2013
|Current application and future perspectives of molecular typing methods to study Clostridium difficile infections|
CW Knetsch, TD Lawley, MP Hensgens, J Corver, MW Wilcox, EJ Kuijper
Eurosurveillance 18 (4), 20381, 2013
|Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during Clostridium difficile infections|
GP Carter, A Chakravorty, TAP Nguyen, S Mileto, F Schreiber, L Li, ...
MBio 6 (3), e00551-15, 2015