| Best practices for single-cell analysis across modalities L Heumos, AC Schaar, C Lance, A Litinetskaya, F Drost, L Zappia, ... Nature Reviews Genetics 24 (8), 550-572, 2023 | 454 | 2023 |
| A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma PatientsA Gene Signature for NK Infiltration and Melanoma Survival J Cursons, F Souza-Fonseca-Guimaraes, M Foroutan, A Anderson, ... Cancer immunology research 7 (7), 1162-1174, 2019 | 245 | 2019 |
| Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma N Jacquelot, C Seillet, M Wang, A Pizzolla, Y Liao, S Hediyeh-Zadeh, ... Nature immunology 22 (7), 851-864, 2021 | 148 | 2021 |
| Combinatorial targeting by microRNAs co-ordinates post-transcriptional control of EMT J Cursons, KA Pillman, KG Scheer, PA Gregory, M Foroutan, ... Cell systems 7 (1), 77-91. e7, 2018 | 110 | 2018 |
| NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS C Louis, F Souza-Fonseca-Guimaraes, Y Yang, D D’silva, T Kratina, ... Journal of Experimental Medicine 217 (5), e20191421, 2020 | 85 | 2020 |
| A Transcriptional Program for Detecting TGFβ-Induced EMT in CancerCharacterization of a TGFβ-Induced EMT Signature M Foroutan, J Cursons, S Hediyeh-Zadeh, EW Thompson, MJ Davis Molecular Cancer Research 15 (5), 619-631, 2017 | 73 | 2017 |
| Metastasis-entrained eosinophils enhance lymphocyte-mediated antitumor immunity S Grisaru-Tal, S Dulberg, L Beck, C Zhang, M Itan, S Hediyeh-Zadeh, ... Cancer Research 81 (21), 5555-5571, 2021 | 69 | 2021 |
| Therapeutic blockade of activin-A improves NK cell function and antitumor immunity J Rautela, LF Dagley, CC De Oliveira, IS Schuster, S Hediyeh-Zadeh, ... Science signaling 12 (596), eaat7527, 2019 | 69 | 2019 |
| Biologically informed deep learning to query gene programs in single-cell atlases M Lotfollahi, S Rybakov, K Hrovatin, S Hediyeh-Zadeh, C Talavera-López, ... Nature Cell Biology 25 (2), 337-350, 2023 | 66 | 2023 |
| TCF-1 limits the formation of Tc17 cells via repression of the MAF–RORγt axis LA Mielke, Y Liao, EB Clemens, MA Firth, B Duckworth, Q Huang, ... Journal of Experimental Medicine 216 (7), 1682-1699, 2019 | 59 | 2019 |
| The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1 CL Carmichael, J Wang, T Nguyen, O Kolawole, A Benyoucef, ... Blood, The Journal of the American Society of Hematology 136 (8), 957-973, 2020 | 50 | 2020 |
| Population-level integration of single-cell datasets enables multi-scale analysis across samples C De Donno, S Hediyeh-Zadeh, AA Moinfar, M Wagenstetter, L Zappia, ... Nature Methods 20 (11), 1683-1692, 2023 | 46 | 2023 |
| Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype M Kojic, T Gawda, M Gaik, A Begg, A Salerno-Kochan, ND Kurniawan, ... Nature communications 12 (1), 2678, 2021 | 40 | 2021 |
| An Erg-driven transcriptional program controls B cell lymphopoiesis AP Ng, HD Coughlan, S Hediyeh-Zadeh, K Behrens, TM Johanson, ... Nature Communications 11 (1), 3013, 2020 | 39 | 2020 |
| Type 2 innate lymphoid cells protect against colorectal cancer progression and predict improved patient survival Q Huang, N Jacquelot, A Preaudet, S Hediyeh-Zadeh, ... Cancers 13 (3), 559, 2021 | 38 | 2021 |
| Cotargeting BCL-2 and MCL-1 in high-risk B-ALL DM Moujalled, DT Hanna, S Hediyeh-Zadeh, G Pomilio, L Brown, ... Blood advances 4 (12), 2762-2767, 2020 | 36 | 2020 |
| Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer S Sharma, CY Chung, S Uryu, J Petrovic, J Cao, A Rickard, N Nady, ... Cell Chemical Biology 30 (10), 1191-1210. e20, 2023 | 33* | 2023 |
| NK cell priming from endogenous homeostatic signals is modulated by CIS RB Delconte, G Guittard, W Goh, S Hediyeh-Zadeh, RJ Hennessy, ... Frontiers in Immunology 11, 75, 2020 | 33 | 2020 |
| Molecular insight into targeting the NK cell immune response to cancer J Rautela, F Souza‐Fonseca‐Guimaraes, S Hediyeh‐Zadeh, ... Immunology and cell biology 96 (5), 477-484, 2018 | 30 | 2018 |
| MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms LH Chi, RSN Cross, RP Redvers, M Davis, S Hediyeh-Zadeh, ... Oncogenesis 11 (1), 38, 2022 | 24 | 2022 |
Melissa J DavisDirector, Computational Biology, Isomorphic LabsVerified email at isomorphiclabs.com
