Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity Y Chien, C Scuoppo, X Wang, X Fang, B Balgley, JE Bolden, P Premsrirut, ... Genes & development 25 (20), 2125-2136, 2011 | 945 | 2011 |
A rapid and scalable system for studying gene function in mice using conditional RNA interference PK Premsrirut, LE Dow, SY Kim, M Camiolo, CD Malone, C Miething, ... Cell 145 (1), 145-158, 2011 | 351 | 2011 |
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms Y Liu, C Chen, Z Xu, C Scuoppo, CD Rillahan, J Gao, B Spitzer, ... Nature 531 (7595), 471-475, 2016 | 258 | 2016 |
Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model A Bric, C Miething, CU Bialucha, C Scuoppo, L Zender, A Krasnitz, Z Xuan, ... Cancer cell 16 (4), 324-335, 2009 | 212 | 2009 |
High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly PE Forni, C Scuoppo, I Imayoshi, R Taulli, W Dastru, V Sala, UAK Betz, ... Journal of Neuroscience 26 (37), 9593-9602, 2006 | 200 | 2006 |
Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma R Taulli, C Scuoppo, F Bersani, P Accornero, PE Forni, S Miretti, A Grinza, ... Cancer research 66 (9), 4742-4749, 2006 | 189 | 2006 |
A tumour suppressor network relying on the polyamine–hypusine axis C Scuoppo, C Miething, L Lindqvist, J Reyes, C Ruse, I Appelmann, ... Nature 487 (7406), 244-248, 2012 | 158 | 2012 |
Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia G Fabbri, AB Holmes, M Viganotti, C Scuoppo, L Belver, D Herranz, ... Proceedings of the National Academy of Sciences 114 (14), E2911-E2919, 2017 | 131 | 2017 |
Unique and shared epigenetic programs of the CREBBP and EP300 acetyltransferases in germinal center B cells reveal targetable dependencies in lymphoma SN Meyer, C Scuoppo, S Vlasevska, E Bal, AB Holmes, M Holloman, ... Immunity 51 (3), 535-547. e9, 2019 | 105 | 2019 |
PTEN action in leukaemia dictated by the tissue microenvironment C Miething, C Scuoppo, B Bosbach, I Appelmann, J Nakitandwe, J Ma, ... Nature 510 (7505), 402-406, 2014 | 54 | 2014 |
Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells S Chatterjee, L Seifried, ME Feigin, DL Gibbons, C Scuoppo, W Lin, ... PloS one 7 (4), e34343, 2012 | 52 | 2012 |
A CRISPR/Cas9 functional screen identifies rare tumor suppressors A Katigbak, R Cencic, F Robert, P Sénécha, C Scuoppo, J Pelletier Scientific reports 6 (1), 38968, 2016 | 47 | 2016 |
RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis R Taulli, P Accornero, A Follenzi, T Mangano, A Morotti, C Scuoppo, ... Cancer gene therapy 12 (5), 456-463, 2005 | 43 | 2005 |
A common functional consequence of tumor-derived mutations within c-MYC AA Chakraborty, C Scuoppo, S Dey, LR Thomas, SL Lorey, SW Lowe, ... Oncogene 34 (18), 2406-2409, 2015 | 38 | 2015 |
Conditional activation of MET in differentiated skeletal muscle induces atrophy T Crepaldi, F Bersani, C Scuoppo, P Accornero, C Prunotto, R Taulli, ... Journal of biological chemistry 282 (9), 6812-6822, 2007 | 33 | 2007 |
Repurposing dasatinib for diffuse large B cell lymphoma C Scuoppo, J Wang, M Persaud, SK Mittan, K Basso, L Pasqualucci, ... Proceedings of the National Academy of Sciences 116 (34), 16981-16986, 2019 | 23 | 2019 |
Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity S Marsilio, H Khiabanian, G Fabbri, S Vergani, C Scuoppo, E Montserrat, ... Leukemia 32 (4), 1040-1043, 2018 | 23 | 2018 |
An in vivo model of Met-driven lymphoma as a tool to explore the therapeutic potential of Met inhibitors P Accornero, G Lattanzio, T Mangano, R Chiarle, R Taulli, F Bersani, ... Clinical cancer research 14 (7), 2220-2226, 2008 | 22 | 2008 |
The oncogenic transcription factor PAX3-FKHR can convert fibroblasts into contractile myotubes C Scuoppo, I Riess, M Schmitt-Ney, P Allegra, PE Forni, F Bersani, ... Experimental cell research 313 (11), 2308-2317, 2007 | 18 | 2007 |
Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma X Chen, Y Li, F Zhu, X Xu, B Estrella, MA Pazos, JT McGuire, ... Nature Communications 14 (1), 4259, 2023 | 5 | 2023 |