Juergen Goetz (Jürgen Götz)
Juergen Goetz (Jürgen Götz)
Queensland Brain Institute, The University of Queensland
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Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils
J Gotz, F Chen, J Van Dorpe, RM Nitsch
Science 293 (5534), 1491-1495, 2001
Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models
LM Ittner, YD Ke, F Delerue, M Bi, A Gladbach, J van Eersel, H Wölfing, ...
Cell 142 (3), 387-397, 2010
Amyloid-β and tau—a toxic pas de deux in Alzheimer's disease
LM Ittner, J Götz
Nature Reviews Neuroscience 12 (2), 67-72, 2011
Animal models of Alzheimer's disease and frontotemporal dementia
J Götz, LM Ittner
Nature Reviews Neuroscience 9 (7), 532-544, 2008
FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations
JM Hébert, T Rosenquist, J Götz, GR Martin
Cell 78 (6), 1017-1025, 1994
Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
V Rhein, X Song, A Wiesner, LM Ittner, G Baysang, F Meier, L Ozmen, ...
Proceedings of the National Academy of Sciences 106 (47), 20057-20062, 2009
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
D Shmerling, I Hegyi, M Fischer, T Blättler, S Brandner, J Götz, T Rülicke, ...
Cell 93 (2), 203-214, 1998
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.
J Götz, A Probst, MG Spillantini, T Schäfer, R Jakes, K Bürki, M Goedert
The EMBO journal 14 (7), 1304-1313, 1995
Tau filament formation in transgenic mice expressing P301L tau
J Götz, F Chen, R Barmettler, RM Nitsch
Journal of Biological Chemistry 276 (1), 529-534, 2001
Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model
G Leinenga, J Götz
Science translational medicine 7 (278), 278ra33-278ra33, 2015
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
A Probst, J Götz, KH Wiederhold, M Tolnay, C Mistl, AL Jaton, M Hong, ...
Acta neuropathologica 99 (5), 469-481, 2000
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice
DC David, S Hauptmann, I Scherping, K Schuessel, U Keil, P Rizzu, ...
Journal of Biological Chemistry 280 (25), 23802-23814, 2005
Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy
J Götz, JR Streffer, D David, A Schild, F Hoerndli, L Pennanen, ...
Molecular psychiatry 9 (7), 664-683, 2004
Tau aggregation and its interplay with amyloid-β
RM Nisbet, JC Polanco, LM Ittner, J Götz
Acta neuropathologica 129 (2), 207-220, 2015
Tau promotes neurodegeneration via DRP1 mislocalization in vivo
B DuBoff, J Götz, MB Feany
Neuron 75 (4), 618-632, 2012
Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Cα
J Götz, A Probst, E Ehler, B Hemmings, W Kues
Proceedings of the National Academy of Sciences 95 (21), 12370-12375, 1998
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models
J Van Eersel, YD Ke, X Liu, F Delerue, JJ Kril, J Götz, LM Ittner
Proceedings of the National Academy of Sciences 107 (31), 13888-13893, 2010
The frontotemporal dementia-motor neuron disease continuum
JR Burrell, GM Halliday, JJ Kril, LM Ittner, J Götz, MC Kiernan, JR Hodges
The Lancet 388 (10047), 919-931, 2016
Amyloid-β and tau complexity—towards improved biomarkers and targeted therapies
JC Polanco, C Li, LG Bodea, R Martinez-Marmol, FA Meunier, J Götz
Nature Reviews Neurology 14 (1), 22-39, 2018
Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils
G Habicht, C Haupt, RP Friedrich, P Hortschansky, C Sachse, J Meinhardt, ...
Proceedings of the National Academy of Sciences 104 (49), 19232-19237, 2007
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