Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models LM Ittner, YD Ke, F Delerue, M Bi, A Gladbach, J van Eersel, H Wölfing, ... Cell 142 (3), 387-397, 2010 | 2128 | 2010 |
Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils J Gotz, F Chen, J Van Dorpe, RM Nitsch Science 293 (5534), 1491-1495, 2001 | 2030 | 2001 |
Amyloid-β and tau—a toxic pas de deux in Alzheimer's disease LM Ittner, J Götz Nature Reviews Neuroscience 12 (2), 67-72, 2011 | 1692 | 2011 |
Animal models of Alzheimer's disease and frontotemporal dementia J Götz, LM Ittner Nature Reviews Neuroscience 9 (7), 532-544, 2008 | 884 | 2008 |
FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations JM Hébert, T Rosenquist, J Götz, GR Martin Cell 78 (6), 1017-1025, 1994 | 808 | 1994 |
Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice V Rhein, X Song, A Wiesner, LM Ittner, G Baysang, F Meier, L Ozmen, ... Proceedings of the National Academy of Sciences 106 (47), 20057-20062, 2009 | 756 | 2009 |
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions D Shmerling, I Hegyi, M Fischer, T Blättler, S Brandner, J Götz, T Rülicke, ... Cell 93 (2), 203-214, 1998 | 646 | 1998 |
Tau filament formation in transgenic mice expressing P301L tau J Götz, F Chen, R Barmettler, RM Nitsch Journal of Biological Chemistry 276 (1), 529-534, 2001 | 588 | 2001 |
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. J Götz, A Probst, MG Spillantini, T Schäfer, R Jakes, K Bürki, M Goedert The EMBO journal 14 (7), 1304-1313, 1995 | 585 | 1995 |
Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model G Leinenga, J Götz Science translational medicine 7 (278), 278ra33-278ra33, 2015 | 581 | 2015 |
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice DC David, S Hauptmann, I Scherping, K Schuessel, U Keil, P Rizzu, ... Journal of Biological Chemistry 280 (25), 23802-23814, 2005 | 478 | 2005 |
The blood-brain barrier: Physiology and strategies for drug delivery R Pandit, L Chen, J Götz Advanced drug delivery reviews 165, 1-14, 2020 | 445 | 2020 |
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein A Probst, J Götz, KH Wiederhold, M Tolnay, C Mistl, AL Jaton, M Hong, ... Acta neuropathologica 99, 469-481, 2000 | 442 | 2000 |
Tau aggregation and its interplay with amyloid-β RM Nisbet, JC Polanco, LM Ittner, J Götz Acta neuropathologica 129, 207-220, 2015 | 405 | 2015 |
Amyloid-β and tau complexity—towards improved biomarkers and targeted therapies JC Polanco, C Li, LG Bodea, R Martinez-Marmol, FA Meunier, J Götz Nature Reviews Neurology 14 (1), 22-39, 2018 | 404 | 2018 |
Tau promotes neurodegeneration via DRP1 mislocalization in vivo B DuBoff, J Götz, MB Feany Neuron 75 (4), 618-632, 2012 | 393 | 2012 |
The frontotemporal dementia-motor neuron disease continuum JR Burrell, GM Halliday, JJ Kril, LM Ittner, J Götz, MC Kiernan, JR Hodges The Lancet 388 (10047), 919-931, 2016 | 385 | 2016 |
Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy J Götz, JR Streffer, D David, A Schild, F Hoerndli, L Pennanen, ... Molecular psychiatry 9 (7), 664-683, 2004 | 382 | 2004 |
Rodent models for Alzheimer disease J Götz, LG Bodea, M Goedert Nature Reviews Neuroscience 19 (10), 583-598, 2018 | 371 | 2018 |
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models J Van Eersel, YD Ke, X Liu, F Delerue, JJ Kril, J Götz, LM Ittner Proceedings of the National Academy of Sciences 107 (31), 13888-13893, 2010 | 329 | 2010 |