Compartmentalization of Mammalian folate-mediated one-carbon metabolism AS Tibbetts, DR Appling Annual review of nutrition 30, 57-81, 2010 | 689 | 2010 |
Compartmentation of folate‐mediated one‐carbon metabolism in eukaryotes DR Appling The FASEB journal 5 (12), 2645-2651, 1991 | 502 | 1991 |
Increased extracellular matrix synthesis and mRNA in mesangial cells grown in high-glucose medium SH Ayo, RA Radnik, WF Glass 2nd, JA Garoni, ER Rampt, DR Appling, ... American Journal of Physiology-Renal Physiology 260 (2), F185-F191, 1991 | 362 | 1991 |
Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice J Momb, JP Lewandowski, JD Bryant, R Fitch, DR Surman, SA Vokes, ... Proceedings of the National Academy of Sciences 110 (2), 549-554, 2013 | 178 | 2013 |
In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units. CK Barlowe, DR Appling BioFactors (Oxford, England) 1 (2), 171-176, 1988 | 151 | 1988 |
Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos ST Pike, R Rajendra, K Artzt, DR Appling Journal of Biological Chemistry 285 (7), 4612-4620, 2010 | 136 | 2010 |
Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae EK Kastanos, YY Woldman, DR Appling Biochemistry 36 (48), 14956-14964, 1997 | 133 | 1997 |
Evidence of a role for retinoic acid (vitamin A-acid) in the maintenance of testosterone production in male rats DR APPLING, F CHYTIL Endocrinology 108 (6), 2120-2123, 1981 | 97 | 1981 |
Carbon-13 NMR detection of folate-mediated serine and glycine synthesis in vivo in Saccharomyces cerevisiae LB Pasternack, DA Laude Jr, DR Appling Biochemistry 31 (37), 8713-8719, 1992 | 87 | 1992 |
Isolation, characterization, and functional expression of cDNAs encoding NADH-dependent methylenetetrahydrofolate reductase from higher plants S Roje, H Wang, SD McNeil, RK Raymond, DR Appling, Y Shachar-Hill, ... Journal of Biological Chemistry 274 (51), 36089-36096, 1999 | 84 | 1999 |
Initiation of Protein Synthesis in Saccharomyces cerevisiae Mitochondria without Formylation of the Initiator tRNA Y Li, WB Holmes, DR Appling, UL RajBhandary Journal of bacteriology 182 (10), 2886-2892, 2000 | 82 | 2000 |
Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary cells P Prasannan, S Pike, K Peng, B Shane, DR Appling Journal of Biological Chemistry 278 (44), 43178-43187, 2003 | 81 | 2003 |
Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine LF Garcia-Martinez, DR Appling Biochemistry 32 (17), 4671-4676, 1993 | 77 | 1993 |
Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae SY Chan, DR Appling Journal of Biological Chemistry 278 (44), 43051-43059, 2003 | 76 | 2003 |
Metabolic role of cytoplasmic isozymes of 5, 10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae MG West, DW Horne, DR Appling Biochemistry 35 (9), 3122-3132, 1996 | 76 | 1996 |
Carbon-13 NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae LB Pasternack, DA Laude Jr, DR Appling Biochemistry 33 (1), 74-82, 1994 | 76 | 1994 |
Mammalian MTHFD2L encodes a mitochondrial methylenetetrahydrofolate dehydrogenase isozyme expressed in adult tissues S Bolusani, BA Young, NA Cole, AS Tibbetts, J Momb, JD Bryant, ... Journal of Biological Chemistry 286 (7), 5166-5174, 2011 | 75 | 2011 |
Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase C Lee, G Kramer, DE Graham, DR Appling Journal of biological chemistry 282 (38), 27744-27753, 2007 | 69 | 2007 |
Metabolic engineering in yeast demonstrates thats-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo S Roje, SY Chan, F Kaplan, RK Raymond, DW Horne, DR Appling, ... Journal of Biological Chemistry 277 (6), 4056-4061, 2002 | 67 | 2002 |
Molecular Genetic Analysis of Saccharomyces cerevisiae C1-Tetrahydrofolate Synthase Mutants Reveals a Noncatalytic Function of the ADE3 Gene Product and … CK Barlowe, DR Appling Molecular and cellular biology 10 (11), 5679-5687, 1990 | 60 | 1990 |