Hoang V. Le
Hoang V. Le
Assistant Professor of Medicinal Chemistry, School of Pharmacy, University of Mississippi
Verified email at olemiss.edu - Homepage
Title
Cited by
Cited by
Year
Trifluoroacetic Anhydride-Catalyzed Oxidation of Isonitriles by DMSO: A Rapid, Convenient Synthesis of Isocyanates
HV Le, B Ganem
Organic Letters 13 (10), 2584-2585, 2011
402011
Inhibition of glycolysis and glutaminolysis: an emerging drug discovery approach to combat cancer
NS Akins, TC Nielson, HV Le
Current topics in medicinal chemistry 18 (6), 494-504, 2018
332018
Method of forming a thermoformed corrugated container and a corrugated container formed thereby
J Lingle, D Stucker, J Covelli
US Patent App. 10/189,807, 2003
222003
A practical and inexpensive ‘convertible’isonitrile for use in multicomponent reactions
HV Le, L Fan, B Ganem
Tetrahedron letters 52 (17), 2209-2211, 2011
202011
Suppression of hepatocellular carcinoma by inhibition of overexpressed ornithine aminotransferase
E Zigmond, AB Ya’acov, H Lee, Y Lichtenstein, Z Shalev, Y Smith, ...
ACS medicinal chemistry letters 6 (8), 840-844, 2015
182015
Design and Mechanism of Tetrahydrothiophene-Based γ-Aminobutyric Acid Aminotransferase Inactivators
HV Le, DD Hawker, R Wu, E Doud, J Widom, R Sanishvili, D Liu, ...
Journal of the American Chemical Society 137 (13), 4525-4533, 2015
182015
Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator …
JI Juncosa, K Takaya, HV Le, MJ Moschitto, PM Weerawarna, ...
Journal of the American Chemical Society 140 (6), 2151-2164, 2018
162018
PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation
R Wu, R Sanishvili, BR Belitsky, JI Juncosa, HV Le, HJS Lehrer, M Farley, ...
Proceedings of the National Academy of Sciences 114 (15), 3891-3896, 2017
132017
Mechanism of Inactivation of GABA Aminotransferase by (E)-and (Z)-(1 S, 3 S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid
H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ...
ACS Chemical Biology 10 (9), 2087-2098, 2015
72015
Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: utility in synthetic and medicinal chemistry
HV Le, B Ganem
Tetrahedron Letters 55 (12), 2003-2005, 2014
72014
A simple, general synthesis of carbonimidic dichlorides
CM Gober, HV Le, B Ganem
Tetrahedron Letters 53 (34), 4536-4537, 2012
72012
Selective targeting by a mechanism-based inactivator against pyridoxal 5′-phosphate-dependent enzymes: Mechanisms of inactivation and alternative turnover
R Mascarenhas, HV Le, KD Clevenger, HJ Lehrer, D Ringe, NL Kelleher, ...
Biochemistry 56 (37), 4951-4961, 2017
52017
Studies on the synthesis of amidoximes from nitroalkanes
G Sanguineti, HV Le, B Ganem
Tetrahedron 67 (52), 10208-10211, 2011
32011
A Practical Synthesis of Isocyanates from Isonitriles: Ethyl 2‐Isocyanatoacetate
HV Le, B Ganem
Organic Syntheses 89, 404-408, 2012
2*2012
Inactivators of toxoplasma gondii ornithine aminotransferase for treating toxoplasmosis and malaria
RB Silverman, HV Le, RL McLeod, DD Hawker
US Patent App. 15/728,714, 2018
12018
Tetrahydrothiophene-based GABA aminotransferase inactivators
RB Silverman, HV Le, DD Hawker
US Patent 9,856,231, 2018
12018
(S)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA aminotransferase inactivators for the treatment of epilepsy, addiction and …
RB Silverman, K Takaya, HV Le, JI Juncosa
US Patent 9,670,141, 2017
12017
Tetrahydrothiophene-based GABA Aminotransferase Inactivators and Analogs Thereof for Treating Neurological Disorders
RB Silverman, HV Le, DD Hawker
US Patent App. 16/252,037, 2019
2019
Tetrahydrothiophene-based GABA aminotransferase inactivators
RB Silverman, HV Le, DD Hawker
US Patent 10,189,807, 2019
2019
(S)-3-Amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid, and Related Compounds as GABA Aminotransferase Inactivators for the Treatment of Epilepsy, Addiction and …
RB Silverman, K Takaya, HV Le, JI Juncosa
US Patent App. 15/991,323, 2018
2018
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