| POT1 loss-of-function variants predispose to familial melanoma CD Robles-Espinoza, M Harland, AJ Ramsay, LG Aoude, V Quesada, ... Nature genetics 46 (5), 478-481, 2014 | 420 | 2014 |
| Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-κB K Gowrishankar, D Gunatilake, SJ Gallagher, J Tiffen, H Rizos, P Hersey PloS one 10 (4), e0123410, 2015 | 241 | 2015 |
| Targeting glutamine transport to suppress melanoma cell growth Q Wang, KA Beaumont, NJ Otte, J Font, CG Bailey, M van Geldermalsen, ... International journal of cancer 135 (5), 1060-1071, 2014 | 235 | 2014 |
| Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development Q Wang, J Tiffen, CG Bailey, ML Lehman, W Ritchie, L Fazli, C Metierre, ... Journal of the National Cancer Institute 105 (19), 1463-1473, 2013 | 210 | 2013 |
| Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression Q Wang, CG Bailey, C Ng, J Tiffen, A Thoeng, V Minhas, ML Lehman, ... Cancer research 71 (24), 7525-7536, 2011 | 192 | 2011 |
| Targeting DNA methylation and EZH2 activity to overcome melanoma resistance to immunotherapy A Al Emran, A Chatterjee, EJ Rodger, JC Tiffen, SJ Gallagher, MR Eccles, ... Trends in immunology 40 (4), 328-344, 2019 | 182 | 2019 |
| Inactivating CUX1 mutations promote tumorigenesis CC Wong, I Martincorena, AG Rust, M Rashid, C Alifrangis, ... Nature genetics 46 (1), 33-38, 2014 | 159 | 2014 |
| Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo JC Tiffen, CG Bailey, C Ng, JEJ Rasko, J Holst Molecular cancer 9, 1-8, 2010 | 126 | 2010 |
| Control of NF‐kB activity in human melanoma by bromodomain and extra‐terminal protein inhibitor I‐BET 151 SJ Gallagher, B Mijatov, D Gunatilake, K Gowrishankar, J Tiffen, W James, ... Pigment cell & melanoma research 27 (6), 1126-1137, 2014 | 98 | 2014 |
| Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling A Heinemann, C Cullinane, R De Paoli-Iseppi, JS Wilmott, D Gunatilake, ... Oncotarget 6 (25), 21507, 2015 | 97 | 2015 |
| Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes JC Tiffen, D Gunatilake, SJ Gallagher, K Gowrishankar, A Heinemann, ... Oncotarget 6 (29), 27023, 2015 | 79 | 2015 |
| The epigenetic regulator I-BET151 induces BIM-dependent apoptosis and cell cycle arrest of human melanoma cells SJ Gallagher, B Mijatov, D Gunatilake, JC Tiffen, K Gowrishankar, L Jin, ... Journal of Investigative Dermatology 134 (11), 2795-2805, 2014 | 68 | 2014 |
| The cancer‐testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells JC Tiffen, CG Bailey, AD Marshall, C Metierre, Y Feng, Q Wang, ... International journal of cancer 133 (7), 1603-1613, 2013 | 68 | 2013 |
| Marked global DNA hypomethylation is associated with constitutive PD-L1 expression in melanoma A Chatterjee, EJ Rodger, A Ahn, PA Stockwell, M Parry, J Motwani, ... Iscience 4, 312-325, 2018 | 67 | 2018 |
| EZH 2: An emerging role in melanoma biology and strategies for targeted therapy J Tiffen, SJ Gallagher, P Hersey Pigment cell & melanoma research 28 (1), 21-30, 2015 | 57 | 2015 |
| Adenoma development in familial adenomatous polyposis and MUTYH‐associated polyposis: somatic landscape and driver genes M Rashid, A Fischer, CH Wilson, J Tiffen, AG Rust, P Stevens, ... The Journal of pathology 238 (1), 98-108, 2016 | 56 | 2016 |
| EZH2 cooperates with DNA methylation to downregulate key tumor suppressors and IFN gene signatures in melanoma J Tiffen, SJ Gallagher, F Filipp, D Gunatilake, A Al Emran, C Cullinane, ... Journal of Investigative Dermatology 140 (12), 2442-2454. e5, 2020 | 52 | 2020 |
| HDAC inhibitors restore BRAF‐inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma SJ Gallagher, D Gunatilake, KA Beaumont, DM Sharp, JC Tiffen, ... International journal of cancer 142 (9), 1926-1937, 2018 | 48 | 2018 |
| Somatic copy number amplification and hyperactivating somatic mutations of EZH2 correlate with DNA methylation and drive epigenetic silencing of genes involved in tumor … J Tiffen, S Wilson, SJ Gallagher, P Hersey, FV Filipp Neoplasia 18 (2), 121-132, 2016 | 48 | 2016 |
| Histone modifications, modifiers and readers in melanoma resistance to targeted and immune therapy SJ Gallagher, JC Tiffen, P Hersey Cancers 7 (4), 1959-1982, 2015 | 45 | 2015 |
