| pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures DEV Pires, TL Blundell, DB Ascher Journal of medicinal chemistry 58 (9), 4066-4072, 2015 | 3900 | 2015 |
| mCSM: predicting the effects of mutations in proteins using graph-based signatures DEV Pires, DB Ascher, TL Blundell Bioinformatics 30 (3), 335-342, 2014 | 977 | 2014 |
| DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability CHM Rodrigues, DEV Pires, DB Ascher Nucleic acids research 46 (W1), W350-W355, 2018 | 929 | 2018 |
| DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach DEV Pires, DB Ascher, TL Blundell Nucleic acids research 42 (W1), W314-W319, 2014 | 857 | 2014 |
| A structural biology community assessment of AlphaFold2 applications M Akdel, DEV Pires, EP Pardo, J Jänes, AO Zalevsky, B Mészáros, ... Nature Structural & Molecular Biology 29 (11), 1056-1067, 2022 | 460 | 2022 |
| DynaMut2: Assessing changes in stability and flexibility upon single and multiple point missense mutations CHM Rodrigues, DEV Pires, DB Ascher Protein Science 30 (1), 60-69, 2021 | 355 | 2021 |
| mCSM-PPI2: predicting the effects of mutations on protein–protein interactions CHM Rodrigues, Y Myung, DEV Pires, DB Ascher Nucleic acids research 47 (W1), W338-W344, 2019 | 315 | 2019 |
| Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD KA Andrews, DB Ascher, DEV Pires, DR Barnes, L Vialard, RT Casey, ... Journal of medical genetics 55 (6), 384-394, 2018 | 235 | 2018 |
| mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance DEV Pires, TL Blundell, DB Ascher Scientific reports 6 (1), 29575, 2016 | 136 | 2016 |
| mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures DEV Pires, DB Ascher Nucleic acids research 44 (W1), W469-W473, 2016 | 124 | 2016 |
| Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance J Phelan, F Coll, R McNerney, DB Ascher, DEV Pires, N Furnham, ... BMC medicine 14, 1-13, 2016 | 123 | 2016 |
| mCSM–NA: predicting the effects of mutations on protein–nucleic acids interactions DEV Pires, DB Ascher Nucleic acids research 45 (W1), W241-W246, 2017 | 115 | 2017 |
| CSM-lig: a web server for assessing and comparing protein–small molecule affinities DEV Pires, DB Ascher Nucleic acids research 44 (W1), W557-W561, 2016 | 112 | 2016 |
| Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’in Italy M Nemethova, J Radvanszky, L Kadasi, DB Ascher, DEV Pires, ... European Journal of Human Genetics 24 (1), 66-72, 2016 | 109 | 2016 |
| Protein cutoff scanning: A comparative analysis of cutoff dependent and cutoff free methods for prospecting contacts in proteins CH da Silveira, DEV Pires, RC Minardi, C Ribeiro, CJM Veloso, ... Proteins: Structure, Function, and Bioinformatics 74 (3), 727-743, 2009 | 109 | 2009 |
| Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma M Jafri, NC Wake, DB Ascher, DEV Pires, D Gentle, MR Morris, ... Cancer discovery 5 (7), 723-729, 2015 | 103 | 2015 |
| In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity DEV Pires, J Chen, TL Blundell, DB Ascher Scientific reports 6 (1), 19848, 2016 | 95 | 2016 |
| Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes DEV Pires, TL Blundell, DB Ascher Nucleic acids research 43 (D1), D387-D391, 2015 | 94 | 2015 |
| Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns DEV Pires, RC de Melo-Minardi, MA dos Santos, CH da Silveira, ... BMC Genomics 12 (Suppl 4), S12, 2011 | 91 | 2011 |
| Prediction and optimization of pharmacokinetic and toxicity properties of the ligand DEV Pires, LM Kaminskas, DB Ascher Computational drug discovery and design, 271-284, 2018 | 88 | 2018 |
David AscherUniversity of Queensland; Baker InstituteVerified email at uq.edu.au
