Michele Mazzanti
Michele Mazzanti
Cellular Physiology Professor, University of Milan, Italy
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Properties of the hyperpolarizing‐activated current (if) in cells isolated from the rabbit sino‐atrial node.
D DiFrancesco, A Ferroni, M Mazzanti, C Tromba
The Journal of physiology 377 (1), 61-88, 1986
Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-Å resolution
SJ Harrop, MZ DeMaere, WD Fairlie, T Reztsova, SM Valenzuela, ...
Journal of Biological Chemistry 276 (48), 44993-45000, 2001
The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition
DR Littler, SJ Harrop, WD Fairlie, LJ Brown, GJ Pankhurst, S Pankhurst, ...
Journal of Biological Chemistry 279 (10), 9298-9305, 2004
ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress
A Kumar, M Mazzanti, M Mistrik, M Kosar, GV Beznoussenko, AA Mironov, ...
Cell 158 (3), 633-646, 2014
The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?
DR Littler, SJ Harrop, SC Goodchild, JM Phang, AV Mynott, L Jiang, ...
FEBS letters 584 (10), 2093-2101, 2010
The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle
SM Valenzuela, M Mazzanti, R Tonini, MR Qiu, K Warton, EA Musgrove, ...
The Journal of physiology 529 (Pt 3), 541, 2000
Ion channels in the nuclear envelope
M Mazzanti, LJ DeFelice, J Cohen, H Malter
Nature 343 (6260), 764-767, 1990
Electrical dimension of the nuclear envelope
M Mazzanti, JO Bustamante, H Oberleithner
Physiological Reviews 81 (1), 1-19, 2001
The timing of the excitatory-to-inhibitory GABA switch is regulated by the oxytocin receptor via KCC2
M Leonzino, M Busnelli, F Antonucci, C Verderio, M Mazzanti, B Chini
Cell reports 15 (1), 96-103, 2016
CLIC1 function is required for β-amyloid-induced generation of reactive oxygen species by microglia
RH Milton, R Abeti, S Averaimo, S DeBiasi, L Vitellaro, L Jiang, ...
Journal of Neuroscience 28 (45), 11488-11499, 2008
Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds
R Wuerth, S Thellung, A Bajetto, M Mazzanti, T Florio, F Barbieri
Drug discovery today 21 (1), 190-199, 2016
Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets
M Peretti, M Angelini, N Savalli, T Florio, SH Yuspa, M Mazzanti
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (10), 2523-2531, 2015
Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity
G Novarino, C Fabrizi, R Tonini, MA Denti, F Malchiodi-Albedi, GM Lauro, ...
Journal of Neuroscience 24 (23), 5322-5330, 2004
Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in …
K Warton, R Tonini, WD Fairlie, JM Matthews, SM Valenzuela, MR Qiu, ...
Journal of Biological Chemistry 277 (29), 26003-26011, 2002
Crystal structure of the soluble form of the redox‐regulated chloride ion channel protein CLIC4
DR Littler, NN Assaad, SJ Harrop, LJ Brown, GJ Pankhurst, P Luciani, ...
The FEBS journal 272 (19), 4996-5007, 2005
Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress
S Averaimo, RH Milton, MR Duchen, M Mazzanti
FEBS letters 584 (10), 2076-2084, 2010
Functional characterization of the NCC27 nuclear protein in stable transfected CHO‐K1 cells
R Tonini, A Ferroni, SM Valenzuela, K Warton, TJ Campbell, SN Breit, ...
The FASEB Journal 14 (9), 1171-1178, 2000
Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current
M Gritti, R Würth, M Angelini, F Barbieri, M Peretti, E Pizzi, A Pattarozzi, ...
Oncotarget 5 (22), 11252, 2014
First ultrastructural autoptic findings of SARS-Cov-2 in olfactory pathways and brainstem
G Bulfamante, D Chiumello, MP Canevini, A Priori, M Mazzanti, ...
Minerva Anestesiologica, 2020
Biochemical and electrophysiological studies on the mechanism of action of PNU-151774E, a novel antiepileptic compound
P Salvati, R Maj, C Caccia, MA Cervini, MG Fornaretto, E Lamberti, ...
Journal of pharmacology and experimental therapeutics 288 (3), 1151-1159, 1999
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