Mechanism of activation of protein kinase JAK2 by the growth hormone receptor AJ Brooks, W Dai, ML O’Mara, D Abankwa, Y Chhabra, RA Pelekanos, ... Science 344 (6185), 1249783, 2014 | 455 | 2014 |
Fibroblasts in cancer: Unity in heterogeneity Y Chhabra, AT Weeraratna Cell 186 (8), 1580-1609, 2023 | 153 | 2023 |
Stromal changes in the aged lung induce an emergence from melanoma dormancy ME Fane, Y Chhabra, GM Alicea, DA Maranto, SM Douglass, MR Webster, ... Nature 606 (7913), 396-405, 2022 | 121 | 2022 |
Role of the growth hormone–IGF-1 axis in cancer Y Chhabra, MJ Waters, AJ Brooks Expert Review of Endocrinology & Metabolism 6 (1), 71-84, 2011 | 97 | 2011 |
NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF ME Fane, Y Chhabra, DEJ Hollingsworth, JL Simmons, L Spoerri, TG Oh, ... EBioMedicine 16, 63-75, 2017 | 88 | 2017 |
BRN 2, a POU erful driver of melanoma phenotype switching and metastasis ME Fane, Y Chhabra, AG Smith, RA Sturm Pigment cell & melanoma research 32 (1), 9-24, 2019 | 66 | 2019 |
Differential response to sustained stimulation by hCG & LH on goat ovarian granulosa cells C Gupta, T Chapekar, Y Chhabra, P Singh, S Sinha, K Luthra Indian Journal of Medical Research 135 (3), 331-340, 2012 | 54 | 2012 |
A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation Y Chhabra, HY Wong, LF Nikolajsen, H Steinocher, A Papadopulos, ... Oncogene 37 (4), 489, 2018 | 52 | 2018 |
Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning JL Bridgford, SM Lee, CMM Lee, P Guglielmelli, E Rumi, D Pietra, ... Blood, The Journal of the American Society of Hematology 135 (4), 287-292, 2020 | 44 | 2020 |
A new mechanism for growth hormone receptor activation of JAK2, and implications for related cytokine receptors MJ Waters, AJ Brooks, Y Chhabra Jak-Stat 3 (2), e29569, 2014 | 37 | 2014 |
Genetic variation in IRF 4 expression modulates growth characteristics, tyrosinase expression and interferon‐gamma response in melanocytic cells Y Chhabra, HXL Yong, ME Fane, A Soogrim, W Lim, DN Mahiuddin, ... Pigment cell & melanoma research 31 (1), 51-63, 2018 | 31 | 2018 |
Growth Hormone Stops Excessive Inflammation After Partial Hepatectomy, Allowing Liver Regeneration and Survival Through Induction of H2‐Bl/HLA‐G M Ishikawa, AJ Brooks, MA Fernández‐Rojo, J Medina, Y Chhabra, ... Hepatology 73 (2), 759-775, 2021 | 30 | 2021 |
sFRP2 supersedes VEGF as an age-related driver of angiogenesis in melanoma, affecting response to anti-VEGF therapy in older patients ME Fane, BL Ecker, A Kaur, GE Marino, GM Alicea, SM Douglass, ... Clinical Cancer Research 26 (21), 5709-5719, 2020 | 29 | 2020 |
GHR signalling: Receptor activation and degradation mechanisms Y Chhabra, CMM Lee, AF Müller, AJ Brooks Molecular and Cellular Endocrinology 520, 111075, 2021 | 28 | 2021 |
Loss of growth hormone–mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity Y Chhabra, CN Nelson, M Plescher, JL Barclay, AG Smith, ... The FASEB Journal 33 (5), 6412, 2019 | 28 | 2019 |
Myeloid-derived suppressor cells are a major source of Wnt5A in the melanoma microenvironment and depend on Wnt5A for full suppressive activity SM Douglass, ME Fane, E Sanseviero, BL Ecker, CH Kugel III, R Behera, ... Cancer research 81 (3), 658-670, 2021 | 27 | 2021 |
Growth hormone activated STAT5 is required for induction of beige fat in vivo CN Nelson, EO List, M Ieremia, L Constantin, Y Chhabra, JJ Kopchick, ... Growth Hormone & IGF Research 42, 40-51, 2018 | 26 | 2018 |
NR4A2 promotes DNA double-strand break repair upon exposure to UVR K Yin, Y Chhabra, R Tropee, YC Lim, M Fane, E Dray, RA Sturm, ... Molecular Cancer Research 15 (9), 1184-1196, 2017 | 14 | 2017 |
CRIM1 is necessary for coronary vascular endothelial cell development and homeostasis S Iyer, Y Chhabra, TJ Harvey, R Wang, HS Chiu, AG Smith, WG Thomas, ... Journal of molecular histology 48, 53-61, 2017 | 13 | 2017 |
Age-dependent loss of HAPLN1 erodes vascular integrity via indirect upregulation of endothelial ICAM1 in melanoma GE Marino-Bravante, AE Carey, L Hüser, A Dixit, V Wang, A Kaur, Y Liu, ... Nature Aging 4 (3), 350-363, 2024 | 7 | 2024 |