Pyrido[1,2-a]pyrimidin-4-one Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors Exhibiting Antioxidant Activity C La Motta, S Sartini, L Mugnaini, F Simorini, S Taliani, S Salerno, ... Journal of Medicinal Chemistry 50 (20), 4917-4927, 2007 | 154 | 2007 |
FOXD1–ALDH1A3 signaling is a determinant for the self-renewal and tumorigenicity of mesenchymal glioma stem cells P Cheng, J Wang, I Waghmare, S Sartini, V Coviello, Z Zhang, SH Kim, ... Cancer research 76 (24), 7219-7230, 2016 | 145 | 2016 |
Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic … R Ottanà, R Maccari, M Giglio, A Del Corso, M Cappiello, U Mura, ... European journal of medicinal chemistry 46 (7), 2797-2806, 2011 | 132 | 2011 |
Sampling protein motion and solvent effect during ligand binding V Limongelli, L Marinelli, S Cosconati, C La Motta, S Sartini, L Mugnaini, ... Proceedings of the National Academy of Sciences 109 (5), 1467-1472, 2012 | 117 | 2012 |
Novel Pyrazolopyrimidine Derivatives as Tyrosine Kinase Inhibitors with Antitumoral Activity in Vitro and in Vivo in Papillary Dedifferentiated Thyroid Cancer A Antonelli, G Bocci, C La Motta, SM Ferrari, P Fallahi, A Fioravanti, ... The Journal of Clinical Endocrinology & Metabolism 96 (2), E288-E296, 2011 | 100 | 2011 |
Design, synthesis and biological evaluation of new classes of thieno [3, 2-d] pyrimidinone and thieno [1, 2, 3] triazine as inhibitor of vascular endothelial growth factor … E Perspicace, V Jouan-Hureaux, R Ragno, F Ballante, S Sartini, ... European journal of medicinal chemistry 63, 765-781, 2013 | 72 | 2013 |
Clinical experience using adjunctive gabapentin in treatment-resistant bipolar mixed states G Perugi, C Toni, G Ruffolo, S Sartini, E Simonini, H Akiskal Pharmacopsychiatry 32 (04), 136-141, 1999 | 64 | 1999 |
How reliable are current docking approaches for structure-based drug design? Lessons from aldose reductase M Zentgraf, H Steuber, C Koch, C La Motta, S Stefania, C Sotriffer, ... ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46 (19), 3575-3578, 2007 | 62 | 2007 |
Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors F Da Settimo, G Primofiore, C La Motta, S Sartini, S Taliani, F Simorini, ... Journal of medicinal chemistry 48 (22), 6897-6907, 2005 | 62 | 2005 |
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model C La Motta, S Sartini, S Salerno, F Simorini, S Taliani, AM Marini, ... Journal of medicinal chemistry 51 (11), 3182-3193, 2008 | 58 | 2008 |
CLM94, a Novel Cyclic Amide with Anti-VEGFR-2 and Antiangiogenic Properties, Is Active against Primary Anaplastic Thyroid Cancer in Vitro and in Vivo A Antonelli, G Bocci, C La Motta, SM Ferrari, P Fallahi, I Ruffilli, ... The Journal of Clinical Endocrinology & Metabolism 97 (4), E528-E536, 2012 | 54 | 2012 |
CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo A Antonelli, G Bocci, P Fallahi, C La Motta, SM Ferrari, C Mancusi, ... The Journal of Clinical Endocrinology & Metabolism 99 (4), E572-E581, 2014 | 53 | 2014 |
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one Ring System as a Useful Template To Obtain Potent Adenosine Deaminase Inhibitors C La Motta, S Sartini, L Mugnaini, S Salerno, F Simorini, S Taliani, ... Journal of medicinal chemistry 52 (6), 1681-1692, 2009 | 53 | 2009 |
Computational studies of epidermal growth factor receptor: docking reliability, three-dimensional quantitative structure− activity relationship analysis, and virtual screening … C La Motta, S Sartini, T Tuccinardi, E Nerini, F Da Settimo, A Martinelli Journal of medicinal chemistry 52 (4), 964-975, 2009 | 50 | 2009 |
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step A Ramunno, S Cosconati, S Sartini, V Maglio, S Angiuoli, V La Pietra, ... European journal of medicinal chemistry 51, 216-226, 2012 | 48 | 2012 |
Pursuing aldose reductase inhibitors through in situ cross-docking and similarity-based virtual screening S Cosconati, L Marinelli, C La Motta, S Sartini, F Da Settimo, AJ Olson, ... Journal of Medicinal Chemistry 52 (18), 5578-5581, 2009 | 44 | 2009 |
A new approach to control the enigmatic activity of aldose reductase A Del-Corso, F Balestri, E Di Bugno, R Moschini, M Cappiello, S Sartini, ... PLoS One 8 (9), e74076, 2013 | 43 | 2013 |
Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells L Quattrini, ELM Gelardi, V Coviello, S Sartini, DM Ferraris, M Mori, ... Journal of Medicinal Chemistry 63 (9), 4603-4616, 2020 | 42 | 2020 |
Evidence for a novel binding site conformer of aldose reductase in ligand-bound state H Steuber, M Zentgraf, C La Motta, S Sartini, A Heine, G Klebe Journal of molecular biology 369 (1), 186-197, 2007 | 41 | 2007 |
From pollen grains to functionalized microcapsules: a facile chemical route using ionic liquids C Chiappe, GC Demontis, V Di Bussolo, MJR Douton, F Rossella, ... Green chemistry 19 (4), 1028-1033, 2017 | 36 | 2017 |