| Small heat shock proteins are molecular chaperones. U Jakob, M Gaestel, K Engel, J Buchner Journal of Biological Chemistry 268 (3), 1517-1520, 1993 | 1703 | 1993 |
| Hsp90 chaperones protein folding in vitro H Wiech, J Buchner, R Zimmermann, U Jakob Nature 358 (6382), 169-170, 1992 | 680 | 1992 |
| Chaperone activity with a redox switch U Jakob, W Muse, M Eser, JCA Bardwell Cell 96 (3), 341-352, 1999 | 626 | 1999 |
| Quantifying changes in the thiol redox proteome upon oxidative stress in vivo LI Leichert, F Gehrke, HV Gudiseva, T Blackwell, M Ilbert, AK Walker, ... Proceedings of the National Academy of Sciences 105 (24), 8197-8202, 2008 | 575 | 2008 |
| Assisting spontaneity: the role of Hsp90 and small Hsps as molecular chaperones U Jakob, J Buchner Trends in biochemical sciences 19 (5), 205-211, 1994 | 515 | 1994 |
| Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase: implications for heat shock in vivo U Jakob, H Lilie, I Meyer, J Buchner Journal of Biological Chemistry 270 (13), 7288-7294, 1995 | 474 | 1995 |
| Oxidant sensing by reversible disulfide bond formation CM Cremers, U Jakob Journal of Biological Chemistry 288 (37), 26489-26496, 2013 | 472 | 2013 |
| Bleach activates a redox-regulated chaperone by oxidative protein unfolding J Winter, M Ilbert, PCF Graf, D Özcelik, U Jakob Cell 135 (4), 691-701, 2008 | 441 | 2008 |
| Thiol-based redox switches in eukaryotic proteins N Brandes, S Schmitt, U Jakob Antioxidants & redox signaling 11 (5), 997-1014, 2009 | 425 | 2009 |
| The role of thiols in antioxidant systems K Ulrich, U Jakob Free Radical Biology and Medicine 140, 14-27, 2019 | 367 | 2019 |
| Polyphosphate is a primordial chaperone MJ Gray, WY Wholey, NO Wagner, CM Cremers, A Mueller-Schickert, ... Molecular cell 53 (5), 689-699, 2014 | 341 | 2014 |
| Protein thiol modifications visualized in vivo LI Leichert, U Jakob PLoS biology 2 (11), e333, 2004 | 295 | 2004 |
| RNA methylation under heat shock control H Bügl, EB Fauman, BL Staker, F Zheng, SR Kushner, MA Saper, ... Molecular cell 6 (2), 349-360, 2000 | 294 | 2000 |
| Bacterial responses to reactive chlorine species MJ Gray, WY Wholey, U Jakob Annual review of microbiology 67, 141-160, 2013 | 291 | 2013 |
| [27] Analysis of chaperone function using citrate synthase as nonnative substrate protein J Buchner, H Grallert, U Jakob Methods in enzymology 290, 323-338, 1998 | 278 | 1998 |
| Thiol-based redox switches B Groitl, U Jakob Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (8), 1335-1343, 2014 | 248 | 2014 |
| XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders AR Mufti, E Burstein, RA Csomos, PCF Graf, JC Wilkinson, RD Dick, ... Molecular cell 21 (6), 775-785, 2006 | 234 | 2006 |
| Redox switch of hsp33 has a novel zinc-binding motif U Jakob, M Eser, JCA Bardwell Journal of Biological Chemistry 275 (49), 38302-38310, 2000 | 222 | 2000 |
| Severe oxidative stress causes inactivation of DnaK and activation of the redox-regulated chaperone Hsp33 J Winter, K Linke, A Jatzek, U Jakob Molecular cell 17 (3), 381-392, 2005 | 205 | 2005 |
| Genetic selection designed to stabilize proteins uncovers a chaperone called Spy S Quan, P Koldewey, T Tapley, N Kirsch, KM Ruane, J Pfizenmaier, R Shi, ... Nature structural & molecular biology 18 (3), 262-269, 2011 | 196 | 2011 |
James BardwellProfessor of Molecular Cellular and Developmental Biology, University of MichiganVerified email at umich.edu
