SHP2 inhibition prevents adaptive resistance to MEK inhibitors in multiple cancer models C Fedele, H Ran, B Diskin, W Wei, J Jen, MJ Geer, K Araki, U Ozerdem, ... Cancer discovery 8 (10), 1237-1249, 2018 | 257 | 2018 |
Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma S Zhang, I Dolgalev, T Zhang, H Ran, DA Levine, BG Neel Nature communications 10 (1), 5367, 2019 | 205 | 2019 |
SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling C Fedele, S Li, KW Teng, CJR Foster, D Peng, H Ran, P Mita, MJ Geer, ... Journal of Experimental Medicine 218 (1), e20201414, 2020 | 168 | 2020 |
Sticking it to cancer with molecular glue for SHP2 H Ran, R Tsutsumi, T Araki, BG Neel Cancer cell 30 (2), 194-196, 2016 | 87 | 2016 |
Genetically defined, syngeneic organoid platform for developing combination therapies for ovarian cancer S Zhang, S Iyer, H Ran, I Dolgalev, S Gu, W Wei, CJR Foster, CA Loomis, ... Cancer discovery 11 (2), 362-383, 2021 | 58 | 2021 |
Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice X Hu, Z Tang, Y Li, W Liu, S Zhang, B Wang, Y Tian, Y Zhao, H Ran, W Liu, ... Scientific reports 5 (1), 12982, 2015 | 53 | 2015 |
Off‐target inhibition by active site‐targeting SHP 2 inhibitors R Tsutsumi, H Ran, BG Neel FEBS open bio 8 (9), 1405-1411, 2018 | 52 | 2018 |
Molecular determinants of uterine receptivity Z Tu, H Ran, S Zhang, G Xia, B Wang, H Wang The International journal of developmental biology 58 (2-3-4), 147-154, 2014 | 46 | 2014 |
Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase H Ran, S Kong, S Zhang, J Cheng, C Zhou, B He, Q Xin, JP Lydon, ... Proceedings of the National Academy of Sciences 114 (18), 4816-4821, 2017 | 35 | 2017 |
PKCδ and θ possibly mediate FSH-induced mouse oocyte maturation via NOX-ROS-TACE cascade signaling pathway Q Chen, W Zhang, H Ran, L Feng, H Yan, X Mu, Y Han, W Liu, G Xia, ... PloS one 9 (10), e111423, 2014 | 30 | 2014 |
Systemic morphine treatment derails normal uterine receptivity, leading to embryo implantation failure in mice X Tang, Y Chen, H Ran, Y Jiang, B He, B Wang, S Kong, H Wang Biology of Reproduction 92 (5), 118, 1-9, 2015 | 22 | 2015 |